Antidiarrheal and Antioxidant Activities of the Aerial Parts of Caralluma dalzielii N. E. Brown

The chemical composition of the hydroethanolic extracts (60% v/v) from the aerial parts of Thymus marschallianus Willd (TM) and Thymus seravschanicus Klokov (TS) from Southern Kazakhstan flora was analyzed together with their hexane fractions. Determination of antibacterial, antifungal and antioxidant activities of both extracts was also performed. RP-HPLC/PDA and HPLC/ESI-QTOF-MS showed that there were some differences between the composition of both extracts. The most characteristic components of TM were rosmarinic acid, protocatechuic acid, luteolin 7-O-glucoside, and apigenin 7-O-glucuronide, while protocatechuic acid, luteolin 7-O-glucoside, luteolin 7-O-glucuronide, and eriodictyol predominated in TS. The content of polyplenols was higher in TS than in TM. The GC-MS analysis of the volatile fraction of both examined extracts revealed the presence of thymol and carvacrol. Additionally, sesquiterpenoids, fatty acids, and their ethyl esters were found in TM, and fatty acid methyl esters in TS. The antioxidant activity of both extracts was similar. The antibacterial activity of TS extract was somewhat higher than TM, while antifungal activity was the same. TS extract was the most active against Helicobacter pylori ATCC 43504 with MIC (minimal inhibitory concentration) = 0.625 mg/mL, exerting a bactericidal effect. The obtained data provide novel information about the phytochemistry of both thyme species and suggest new potential application of TS as a source of bioactive compounds, especially with anti-H. pylori activity.

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Essential Oil of Deverra tortuosa Aerial Parts: Detailed Chemical Profile, Allelopathic, Antimicrobial, and Antioxidant Activities

Chemistry & Biodiversity ◽

10.1002/cbdv.202000914 ◽

2021 ◽

Vol 18 (4) ◽

Author(s):

Eman M. Fayed ◽

Ahmed M. Abd‐EIGawad ◽

Abdelsamed I. Elshamy ◽

El‐Sayed F. El‐Halawany ◽

Yasser A. EI‐Amier

Keyword(s):

Essential Oil ◽

Antioxidant Activities ◽

Chemical Profile ◽

Aerial Parts ◽

Detailed Chemical

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Phytochemistry and Biological Activities of Iris Species Growing in Iraqi Kurdistan and Phenolic Constituents of the Traditional Plant Iris postii

Molecules ◽

10.3390/molecules26020264 ◽

2021 ◽

Vol 26 (2) ◽

pp. 264

Author(s):

Hawraz Ibrahim M. Amin ◽

Faiq H. S. Hussain ◽

Soran K. Najmaldin ◽

Zaw Min Thu ◽

Mohammed Farhad Ibrahim ◽

...

Keyword(s):

Antioxidant Activities ◽

Biological Activities ◽

Radical Scavenging ◽

Chromatographic Separations ◽

Traditional Use ◽

Methanolic Extracts ◽

Aerial Parts ◽

Traditional Remedies ◽

Phenolic Constituents ◽

Total Antioxidant

A dozen Iris species (Iridaceae) are considered traditional remedies in Kurdistan, especially for treating inflammations. Phytochemical studies are still scarce. The information reported in the literature about Iris species growing in Kurdistan has been summarized in the first part of this paper, although, except for Iris persica, investigations have been performed on vegetal samples collected in countries different from Kurdistan. In the second part of the work, we have investigated, for the first time, the contents of the methanolic extracts of Iris postii aerial parts and rhizomes that were collected in Kurdistan. Both extracts exhibited a significant dose-dependent free radical scavenging and total antioxidant activities, comparable to those of ascorbic acid. Medium-pressure liquid chromatographic separations of the two extracts afforded l-tryptophan, androsin, isovitexin, swertisin, and 2″-O-α-l-rhamnopyranosyl swertisin from the aerial parts, whereas ε-viniferin, trans-resveratrol 3,4′-O-di-β-d-glucopyranoside, and isotectorigenin were isolated from the rhizomes. This is the first finding of the last three metabolites from an Iris species. The various remarkable biological activities of isolated compounds scientifically sustain the traditional use of I. postii as a medicinal plant.

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Antidiabetic and Antioxidant Activities of Major Flavonoids of Cynanchum acutum L. (Asclepiadaceae) Growing in Egypt

Zeitschrift für Naturforschung C ◽

10.1515/znc-2008-9-1008 ◽

2008 ◽

Vol 63 (9-10) ◽

pp. 658-662 ◽

Cited By ~ 15

Author(s):

Ghada A. Fawzy ◽

Hossam M. Abdallah ◽

Mohamed S. A. Marzouk ◽

Fathy M. Soliman ◽

Amany A. Sleem

Keyword(s):

Blood Glucose ◽

Spectroscopic Data ◽

Methanolic Extract ◽

Antioxidant Activities ◽

First Report ◽

Insulin Levels ◽

Butanol Fraction ◽

Aerial Parts ◽

First Time

Seven flavonoids were isolated from the butanol fraction of the methanolic extract of the aerial parts of Cynanchum acutum L. (Asclepiadaceae). All of which have been isolated for the first time from the genus Cynanchum. Their structures were established as quercetin 3-O-β-galacturonopyranoside (1), quercetin 7-O-β-glucopyranoside (2), tamarixtin 3-O-β-galacturonopyranoside (3), kaempferol 3-O-β-galacturonopyranoside (4), 8-hydroxyquercetin 3-O-β-galactopyranoside (5), tamarixtin 3-O-α-rhamnopyranoside (6), and tamarixtin 7-O-α-arabinopyranoside (7) on the basis of their chromatographic properties, chemical and spectroscopic data. The major isolated flavonoids 1, 2 and 3 were found to exhibit significant antioxidant and antidiabetic activities (by measuring blood glucose and insulin levels). This is the first report about the antioxidant and antidiabetic activities of compounds 1 - 3.

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In vitro antimicrobial and antioxidant activities of the essential oil of Craniotome furcata

Journal of Applied and Natural Science ◽

10.31018/jans.v2i1.95 ◽

2010 ◽

Vol 2 (1) ◽

pp. 57-62 ◽

Cited By ~ 6

Author(s):

R. K. Joshi

Keyword(s):

Free Radical ◽

Essential Oil ◽

Radical Cation ◽

Steam Distillation ◽

Antioxidant Activities ◽

Gram Negative Bacteria ◽

Gram Negative ◽

Aerial Parts ◽

Tube Dilution

The aim of present study was, to investigate the essential oil of Craniotome furcata for its antimicrobial and antioxidant activities. The essential oil was obtained by steam distillation of the flowering aerial parts of C. furcata. The oil was tested for its antimicrobial activity in vitro against four Gram-positive, four Gram-negative bacteria and three fungi, by using disk diffusion and tube dilution methods. The antioxidant potential of the essential oil was investigated by two different models DPPH free radical and ABTS free radical cation scavenging. The essential oil was effective against all the tested microorganisms, with minimum inhibitory concentrations (MICs) ranged from 4.11±1.44 to 0.30±0.10 mg/ml. The oil showed antioxidant activity in DPPH free radical and ABTS free radical cation scavenging model. The results of this study revealed that the essential oil of C. furcata possesses antimicrobial and antioxidant activities.

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Anti-osteoporotic and antioxidant activities of chemical constituents of the aerial parts of Ducrosia ismaelis

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2014.05.077 ◽

2014 ◽

Vol 24 (15) ◽

pp. 3434-3439 ◽

Cited By ~ 9

Author(s):

Abubaker M.A. Morgan ◽

Hyun Woo Lee ◽

Sang-Hyun Lee ◽

Chi-Hwan Lim ◽

Hae-Dong Jang ◽

...

Keyword(s):

Antioxidant Activities ◽

Chemical Constituents ◽

Aerial Parts

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Phytochemical profile, antimicrobial, antioxidant and antiobesity activities of Scolymus angiospermus Gaertn. Four fractions from Jericho/Palestine

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2017-0127 ◽

2018 ◽

Vol 15 (3) ◽

Cited By ~ 2

Author(s):

Nidal Jaradat ◽

Saad Al-Lahham

Keyword(s):

Antioxidant Activities ◽

Past History ◽

Culture Collection ◽

Natural Food ◽

Bacterial Strains ◽

Food Preservatives ◽

Fungal Strains ◽

Antibacterial And Antifungal Activities ◽

Aerial Parts ◽

Phytochemical Profile

Abstract Background Many recent studies have shown that medicinal plants, which have been used worldwide through the past history in the folkloric medicine, harbor a significant number of novel metabolic compounds with potent pharmacological properties. In several countries, the aerial parts of the Scolymus angiospermus plant have been used as a food supply and as a folkloric medicinal plant. The current study aimed is to investigate the antimicrobial, antilipase, antioxidant activities and phytochemical profile of methanolic, hexane, aqueous and ethyl acetate fractions obtained from the aerial parts of S. angiospermus. Methods Phytochemical assessments were based on standard analytical methods. The obtained fractions were evaluated for their antioxidant capacity and their antilipase activity using 2,2-diphenyl-1-picrylhydrazyl and porcine pancreatic lipase inhibitory tests, respectively. Antimicrobial activity of the obtained fractions was evaluated using broth microdilution assay against several American Type Culture Collection bacterial and fungal strains and Methicillin-Resistant Staphylococcus aureus clinical isolate. Results Our data showed that of all obtained fractions used in the above-mentioned assays, both of methanolic and aqueous fractions, had the highest content of flavonoids (24.93 ± 2.11 and 12.21 ± 2.11 mg QUE/g, respectively) and phenolic compounds (96.28 ± 2.87 and 91.25 ± 2.63 mg of GAEq/g, respectively) as well as the best levels of both antioxidant (half maximal inhibitory concentration (IC50) 13.67 ± 1.44 and 14.69 ± 1.97 µg/ml, respectively) and antilipase (IC50 134.89 ± 1.65 and 269.15 ± 2.33 µg/ml, respectively) activities. In addition, these fractions exhibited various levels of both antibacterial and antifungal activities. Hydrophilic fractions were more potent against the investigated bacterial strains, while hydrophobic fractions were more potent against the investigated fungal strains. Conclusions The hydrophilic fractions derived from S. angiospermus have shown the best antioxidant and antilipase effects. This is may be due to the high contents of phenols and/or flavonoids. However, further investigations are essential to isolate and identify the antioxidant, antilipase and antimicrobial compounds. Our data provide significant evidence that S. angiospermus can be very useful in the prevention and treatment of various infectious and non-infectious chronic diseases and as natural food preservatives.

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Phytochemistry and Antioxidant Activity of Aerial Parts of Phagnalon sordidum L.

Planta Medica ◽

10.1055/a-0953-5984 ◽

2019 ◽

Vol 85 (11/12) ◽

pp. 1008-1015 ◽

Cited By ~ 1

Author(s):

Hanene Cherchar ◽

Immacolata Faraone ◽

Massimiliano DʼAmbola ◽

Chiara Sinisgalli ◽

Fabrizio Dal Piaz ◽

...

Keyword(s):

Antioxidant Activity ◽

Ion Trap ◽

Carcinoma Cell ◽

Antioxidant Activities ◽

Aerial Parts ◽

Orbitrap Mass Spectrometry ◽

Natural Monoterpene ◽

Hepatocellular Carcinoma Cell Line ◽

Human Hepatocellular Carcinoma Cell

AbstractOne new natural monoterpene, 5-O-β-d-glucopyranosyl-2-hydroxy-p-cymene (1), and 11 known compounds were isolated through a biologically oriented approach from the aerial parts of Phagnalon sordidum L. The most active extract and fractions were selected using 3 complementary antioxidant activity assays. Results and the different methods were compared by relative antioxidant capacity index. In addition, the most active extract of P. sordidum was subjected to liquid chromatography coupled with electrospray ionization hybrid linear ion trap quadrupole Orbitrap mass spectrometry to quantify secondary metabolites. Antioxidant activities of ethyl acetate extract, and purified 3,4-dihydroxyacetophenone (3) and nebrodenside A (7) were demonstrated by in vitro cell free model assays, and their protective effect against H2O2-induced oxidative stress in a HepG2 (human hepatocellular carcinoma) cell line was established.

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