Antidiabetic and Antihyperlipidemic Activity of Canthium parviflorum Extracts in Streptozotocin-Induced Diabetic Rats

2016 ◽  
Vol 5 (4) ◽  
pp. 181-190
Author(s):  
Neelakanth M. Jeedi ◽  
B. C. Koti
Keyword(s):  
Diabetic Rats ◽  
Antihyperlipidemic Activity

scholarly journals ARISTOLOCHIA BRACTEOLATA – ANTIHYPERGLYCEMIC AND ANTIHYPERLIPIDEMIC ACTIVITY IN DEXAMETHASONE-INDUCED DIABETIC RAT MODEL

2017 ◽  
Vol 10 (8) ◽  
pp. 75
Author(s):  
Ganga Rajum ◽  
Hema Sundar Reddy T ◽  
Hema Sundar Reddy T
Keyword(s):  
Blood Glucose ◽  
Methanolic Extract ◽  
Density Lipoprotein ◽  
Diabetic Rats ◽  
Diabetic Rat ◽  
Standard Drug ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Antihyperlipidemic Activity ◽  
Aristolochia Bracteolata

  Objective: The present study was aimed to evaluate antihyperglycemic and antihyperlipidemic activities of methanolic extract of Aristolochia bracteolata (MEAB) against dexamethasone-induced diabetic rat model.Methods: Methanolic extract was prepared by soxhlet extraction and was evaluated for antihyperglycemic and antihyperlipidemic activity using dexamethasone-induced model. The MEAB was administered orally at a dose of 200 and 400 mg/kg body weight glibenclamide was used as standard drug. On 0th and 11th day, blood was collected by retro-orbit plexus.Results: In this model blood glucose levels were determined on 0th and 11th days and MEAB significantly reduced the blood glucose levels in diabetic rats. The effect of MEAB on serum lipid profile such as total cholesterol (TC), triglycerides (TGs), low-density lipoprotein (LDL), very LDL (VLDL), and high-density lipoprotein (HDL) was also measured on the 11th day in the diabetic rats. Significant reduction in TC, TGs, LDL, and VLDL levels and improvement in HDL level were observed in diabetic rats.Conclusion: From the results, it was found that the MEAB possess antihyperglycemic and antihyperlipidemic activities.

scholarly journals ANTIHYPERGLYCEMIC AND ANTIHYPERLIPIDEMIC ACTIVITY OF JATROPHA GOSSYPIFOLIA METHANOLIC EXTRACT IN STREPTOZOTOCIN-NICOTINAMIDE INDUCED DIABETIC RATS

2017 ◽  
Vol 10 (11) ◽  
pp. 326 ◽  
Author(s):  
Issac Praveen Kumar ◽  
Ishan Malhotra ◽  
Sujatha Sundaresan ◽  
Alwin Dev
Keyword(s):  
Liver Function ◽  
Glycogen Content ◽  
Methanolic Extract ◽  
Density Lipoprotein ◽  
Experimental Period ◽  
Liver Glycogen ◽  
Treated Group ◽  
Diabetic Rats ◽  
Antihyperlipidemic Activity ◽  
Jatropha Gossypifolia

  Objective: The objective of the present study is to explore the antihyperglycemic and antihyperlipidemic activities of Jatropha gossypifolia methanolic extract (ME) in streptozotocin (STZ)-nicotinamide (NIC) induced diabetic model.Methods: Type II diabetes was induced by a single dose of NIC (110 mg/kg) and STZ (50 mg/kg b.w.) intraperitoneally. The diabetic animals were treated with ME (50 mg/kg and 100 mg/kg b.w.) of J. gossypifolia. At the end of experimental period, the effect of the ME on creatinine level, triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very LDL (VLDL) were analyzed. Liver function parameters such as glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) were analyzed and liver glycogen content was estimated spectrophotometrically. After scarification of animals, the liver was collected and subjected to histopathology analysis. Glycogen content was estimated spectrophotometrically.Results: The ME treated diabetic rats showed a significant increase in HDL level and a decrease in creatinine, TG, TC, and VLDL levels. The treated group showed a significant decrease in liver function parameters such as GOT and GPT levels and significantly increased the liver glycogen content.Conclusion: These findings demonstrate that ME possess antihyperglycemic and antihyperlipidemic activity against STZ - NIC induced diabetic rats.

Antidiabetic and antihyperlipidemic activity of ethyl acetate:Isopropanol (1:1) fraction of Vernonia anthelmintica seeds in Streptozotocin induced diabetic rats

2010 ◽  
Vol 48 (2) ◽  
pp. 495-501 ◽  
Author(s):  
Shaik Sameena Fatima ◽  
Maddirala Dilip Rajasekhar ◽  
Kondeti Vinay Kumar ◽  
Mekala Thur Sampath Kumar ◽  
Kasetti Ramesh Babu ◽  
...  
Keyword(s):  
Diabetic Rats ◽  
Antihyperlipidemic Activity ◽  
Vernonia Anthelmintica

Antihyperglycemic and Antihyperlipidemic Activity of Sida spinosa linn. Root in Streptozotocin- Induced Diabetic Rats

2015 ◽  
Vol 5 (2) ◽  
pp. 124-136
Author(s):  
Ibrahim Shaikh ◽  
Preeti Kulkarni ◽  
Basheerahmed Mannasaheb ◽  
Basel Abdel-Wahab
Keyword(s):  
Diabetic Rats ◽  
Antihyperlipidemic Activity ◽  
Sida Spinosa

Antidiabetic and antihyperlipidemic activity of Pithecellobium dulce (Roxb.) Benth seeds extract in streptozotocin-induced diabetic rats

2015 ◽  
Vol 7 (3) ◽  
pp. 263-273 ◽  
Author(s):  
Dnyaneshwar Madhukar Nagmoti ◽  
Pankaj Sudhakar Kothavade ◽  
Vipin Dipak Bulani ◽  
Nitin Bhanudas Gawali ◽  
Archana Ramesh Juvekar
Keyword(s):  
Diabetic Rats ◽  
Antihyperlipidemic Activity

scholarly journals Antidiabetic and antihyperlipidemic activity of Piper longum root aqueous extract in STZ induced diabetic rats

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Shaik Abdul Nabi ◽  
Ramesh Babu Kasetti ◽  
Swapna Sirasanagandla ◽  
Thandaiah Krishna Tilak ◽  
Malaka Venkateshwarulu Jyothi Kumar ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Diabetic Rats ◽  
Piper Longum ◽  
Antihyperlipidemic Activity
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