scholarly journals The Person Symbol in Clinical Medicine: A Correlation of Picture Drawings with Structural Lesions of the Brain

1961 ◽  
Vol 2 (23) ◽  
pp. 908-908
Keyword(s):  
Clinical Medicine ◽  
The Brain

Narcotic Poisoning of Children (1) Through Accidental Ingestion of Methadone and (2) in utero

PEDIATRICS ◽  
1974 ◽  
Vol 54 (3) ◽  
pp. 329-332
Author(s):  
Saul Blatman
Keyword(s):  
Gastrointestinal Tract ◽  
Clinical Medicine ◽  
Well Being ◽  
Pharmacological Action ◽  
In Utero ◽  
Abuse Liability ◽  
Practice Of Medicine ◽  
Life Threatening ◽  
Repeated Use ◽  
The Brain

Narcotics have been known to man since prehistoric times, and they continue to be among the most used analgesics in the practice of medicine. They comprise a group of drugs whose analgesic effect is coupled with euphoria and somnolence. In addition, their spasmogenic effect on smooth muscle has made them useful agents in the alleviation of certain gastrointestinal tract symptoms. For most narcotics, therapeutic dosage does not produce serious untoward effects. Unfortunately, they have a depressant effect on respiration by directly influencing the respiratory center of the brain. This may be life threatening when recommended dosages are exceeded. Narcotics have been abused since the recognition that they can induce euphoria and a feeling of well being. Tolerance and physical and psychological dependence result from their repeated use. The occurrence of withdrawal symptomatology in humans using these drugs repeatedly helps to produce a pattern of drug dependence; an individual has but to repeat a dose of drug in order to prevent withdrawal symptoms. Abuse liability is thus great. All narcotics share this addiction potential. Those most frequently prescribed in clinical medicine are morphine, trieperidine, codeine and methadone. Heroin (diacetylmorphine), the most commonly abused narcotic, available only illicitly, is not prescribed in clinical practice. After injection, it is hydrolyzed to morphine which produces its pharmacological action. While morphine and heroin are absorbed only following parenteral administration, some narcotics are absorbed readily from the gastrointestinal tract as well as after injection (methadone, codeine, meperidine). Regardless of the mode of administration, narcotics taken by a pregnant addict readily pass the placental barrier and are capable of producing effects on the infant in utero and after birth.

MARKERS OF NEUROVISULATION IN MIGRAINE DIAGNOSTICS

2019 ◽  
pp. 108-113
Author(s):  
M. P. Ostashko ◽  
T. I. Nasonova
Keyword(s):  
Magnetic Resonance Imaging ◽  
Significant Contribution ◽  
Clinical Medicine ◽  
Imaging Techniques ◽  
Diagnostic Methods ◽  
Resonance Imaging ◽  
Functional Changes ◽  
Magnetic Resonance Imaging Techniques ◽  
The Brain ◽  
Neuroimaging Techniques

In clinical medicine, the diagnosis of migraine is based on anamnesis and symptoms, and instrumental diagnostic methods are considered non-informative. Numerous studies of the brain, during headaches and between them, have made a significant contribution to understanding the pathophysiology of migraines. Structural and functional changes in the migraine brain are revealed by advanced magnetic resonance imaging techniques, and attempts to detect the visualization markers of this disease progressively increase. This overview article aims to summarize the results of recent studies that reflect achievements in understanding the pathophysiology of migraine, as well as the possibility of using neuroimaging techniques in diagnosing migraines.

All in the Brain?

Neuro ◽  
2013 ◽  
Author(s):  
Nikolas Rose ◽  
Joelle M. Abi-Rached
Keyword(s):  
Nineteenth Century ◽  
Psychiatric Disorders ◽  
Clinical Medicine ◽  
Clinical Work ◽  
Psychiatric Classification ◽  
The Troubles ◽  
The Relationship ◽  
The Brain ◽  
The Way

This chapter focuses on the question of diagnosis of psychiatric disorders and examines the relationship between neuroscience and psychiatry from this perspective. Despite the penetrating gaze of neuroscience, which has opened up the brain to vision in so many ways, psychiatric classification remains superficial. This neuromolecular vision seems incapable of grounding the clinical work of psychiatry in the way that has become routine in other areas of medicine. Despite the conviction of most practitioners that they deal with conditions that have a corporeal seat in the brain of the afflicted individual, psychiatry has failed to establish the bridge that, from the nineteenth century on, underpinned the epistemology of modern clinical medicine—the capacity to link the troubles of the troubled and troubling individuals who are its subjects with the vital anomalies that underpin them.

MODELS OF BIOMODULATION IN A MICROPROCESSOR SYSTEM OF SUPER LOW INTENSIVE MICROWAVE RADIATION, INTENDED FOR TRANSFORMATION OF BRAIN NEURODYNAMIC ACTIVITY AND MODIFICATION OF THE FUNCTIONAL STATE OF THE PATIENT

2021 ◽  
pp. 160-168
Author(s):  
Феликс Андреевич Пятакович ◽  
Ольга Владимировна Мевша ◽  
Татьяна Игоревна Якунченко ◽  
Кристина Феликсовна Макконен
Keyword(s):  
Microwave Radiation ◽  
Functional State ◽  
Clinical Medicine ◽  
Interdisciplinary Collaboration ◽  
Power Level ◽  
Experimental Studies ◽  
Physical Nature ◽  
Microprocessor System ◽  
Low Intensity ◽  
The Brain

Еще в 60-70 годы XX-го столетия в экспериментальных исследованиях новосибирских ученых, выполненных под руководством академика В.П.Казначеева, была установлена роль сверхслабых физических полей в развитии цитопатологического действия биологических объектов вирусной природы, агентов химической и физической природы. В последние годы в экспериментальной и клинической медицине наряду с использованием низкоинтенсивных крайне высокочастотных миллиметровых излучений (менее 10 мВт/см) успешно используют СВЧ генераторы сверхнизкой интенсивности сантиметрового диапазона длин волн на уровне мощности, не превышающих 10 мкВт/см. Подобное СВЧ излучение сверхмалой мощности, осуществляемое на частоте колебаний кластеров воды первого порядка, способствует нормализации процессов метаболизма. Настоящее исследование выполнено в соответствии с планами проблемной комиссии по «хронобиологии и хрономедицине» РАН. На основе междисциплинарного сотрудничества была сформирована виртуальная команда исследователей работающих в разных университетах страны и включавшая математиков, системных программистов, инженеров и врачей-исследователей. При этом для реализации целей и задач исследования использовалась, так называемая, линейная модель движения потока информации из научной лаборатории в клиническую практику (from bench to bedside). В связи с чем, нами был реализован проект, направленный на разработку технической системы модульного типа, предназначенной для генерации СВЧ излучения с заданными свойствами. В микроконтроллере СВЧ генератора был запрограммирован цифровой аналог сигналов отражающих нейродинамические процессы мозга. В настоящей статье показана электрофизиологическая эффективность сверхнизко интенсивных излучений сантиметрового диапазона длин волн модулированных низкочастотными сигналами подобных ритму ЭЭГ и с циклической изменяемостью скважности. В клинических исследованиях у больных сахарным диабетом II с сопутствующей гипертонической болезнью на основе теста Спилбергера показана трансформация патологической нейродинамической активности мозга с последующей модификацией функционального состояния пациента. Рассмотрены результаты не эффективного воздействия, эффективного воздействия и успешного воздействия с изменениями динамики уровня пластичности нейродинамической активности мозга Back in the 60s-70s of the 20th century, in the experimental studies of Novosibirsk scientists, carried out under the leadership of Academician V.P. Kaznacheev, the role of super weak physical fields in the development of the cytopathological action of biological objects of viral nature, agents of chemical and physical nature was established. In recent years, in experimental and clinical medicine, along with the use of low-intensity extremely high-frequency millimeter radiation (less than 10 mW / cm), microwave generators of super low intensity of the centimeter wavelength range have been successfully used at a power level not exceeding 10 μW/cm. Such super low-power microwave radiation, is realized at the frequency of vibrations of first-order water clusters, contributes to the normalization of metabolic processes. The present study was work out in accordance with the plans of the problem commission on "chronobiology and chronomedicine" of the Russian Academy of Sciences. On the basis of interdisciplinary collaboration, a virtual team of researchers working in different universities in the country was formed and included mathematicians, systems programmers, engineers and medical researchers. At the same time, to implement the goals and objectives of the study, the so-called linear model of the flow of information from the scientific laboratory to clinical practice (from bench to bedside) was used. In this connection, we have implemented a project aimed at developing a modular-type technical system designed to generate microwave radiation with desired properties. In the microcontroller of the microwave generator, a digital analogue of signals reflecting the neurodynamic processes of the brain was programmed. This article shows the electrophysiological efficiency of super-low-intensity radiation in the centimeter range of wavelengths modulated by low-frequency signals similar to the EEG rhythm. In experimental studies in patients with diabetes mellitus II with concomitant hypertension, the transformation of the pathological neurodynamic activity of the brain with the subsequent modification of the patient's functional state has been shown. The results of ineffective influence, effective influence and successful influence with changes in the dynamics of the level of plasticity of neurodynamic activity of the brain are considered

Victor Horsley

2022 ◽  
Author(s):  
Michael J. Aminoff
Keyword(s):  
Brain Tumours ◽  
Clinical Medicine ◽  
General Medical Council ◽  
Medical Council ◽  
Science And Politics ◽  
The Many ◽  
Brain And Spinal Cord ◽  
Medical Defence ◽  
The Brain ◽  
Association Medical

Sir Victor Horsley (1857–1916) was a pioneer who shaped the development of neurosurgery and the direction of clinical medicine through his work with the British Medical Association, Medical Defence Union, and General Medical Council. Before the nervous system could be imaged, Horsley operated successfully on the brain and spinal cord, and performed palliative procedures on patients dying from brain tumours. Nevertheless, he became a social pariah due to his support for nationalised health insurance, child welfare and women's rights, amongst other causes. In this fascinating biography, leading neurologist Dr Michael J. Aminoff places Horsley's life and work in the context of the society in which he lived and explores his influence on the development of neurosurgery and social policies still in effect. The many underlying themes to the book include the interplay of science and politics, and the responsibility of physicians to themselves and for the welfare of society.

MARKERS OF NEUROVISULATION IN MIGRAINE DIAGNOSTICS

2019 ◽  
pp. 108-113
Author(s):  
M. P. Ostashko ◽  
T. I. Nasonova
Keyword(s):  
Magnetic Resonance Imaging ◽  
Significant Contribution ◽  
Clinical Medicine ◽  
Imaging Techniques ◽  
Diagnostic Methods ◽  
Resonance Imaging ◽  
Functional Changes ◽  
Magnetic Resonance Imaging Techniques ◽  
The Brain ◽  
Neuroimaging Techniques

In clinical medicine, the diagnosis of migraine is based on anamnesis and symptoms, and instrumental diagnostic methods are considered non-informative. Numerous studies of the brain, during headaches and between them, have made a significant contribution to understanding the pathophysiology of migraines. Structural and functional changes in the migraine brain are revealed by advanced magnetic resonance imaging techniques, and attempts to detect the visualization markers of this disease progressively increase. This overview article aims to summarize the results of recent studies that reflect achievements in understanding the pathophysiology of migraine, as well as the possibility of using neuroimaging techniques in diagnosing migraines.

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