scholarly journals applicable for treating diabetic foot infection?’ A new evidence-based regional study on culture and sensitivity patterns in Terengganu population

2014 ◽  
Vol 8 (1) ◽  
pp. 42-45 ◽  
Author(s):  
SD Balakrishnan ◽  
NJ Shahid ◽  
TM Fairuz ◽  
IMA Ramdhan
Keyword(s):  
Diabetic Foot ◽  
Evidence Based ◽  
Regional Study ◽  
Diabetic Foot Infection ◽  
Culture And Sensitivity ◽  
New Evidence

scholarly journals Study on bacteriological profile and antibiotic susceptibility in diabetic foot infection in a teaching hospital, Telangana

2021 ◽  
Vol 11 (2) ◽  
pp. 315-320
Author(s):  
Divya Pothati ◽  
B. Uday Kiran
Keyword(s):  
Diabetic Foot ◽  
Antibiotic Susceptibility ◽  
Treatment Plan ◽  
Coagulase Negative Staphylococci ◽  
Cross Sectional ◽  
Female Ratio ◽  
Gram Negative ◽  
Diabetic Foot Infection ◽  
Bacteriological Profile ◽  
Culture And Sensitivity

Diabetic foot is one of the most significant complications of diabetes, Chronic infections are caused by Enterococci, various Enterobacteriaceae obligate anaerobes, Pseudomonas aeruginosa. To study bacteriological profile and antibiotic susceptibility in diabetic foot infection. Cross sectional study was done in 110 diabetic foot infection cases in the Department of Microbiology, Prathima Institute of Medical Sciences, Nagunuru, Karimnagar, Telangana. The grading of diabetic foot ulcers was done according to Wagner’s Classification system. The samples were collected from the exudates and ulcers. Gram stain was done and standard protocol for culture and sensitivity was followed for all the cases.A total of 110 cases were studied. The patient age ranged from 35 to 75 years and the male to female ratio was 2:1. Out of 110 isolates, 72.7% isolates were Gram negative bacilli with P. aeruginosa 31.8% being the predominant followed by E.coli 27.2%, K.pneumoniae 10%, P.mirabilis 4.5%, S.aureus 12.7% was the predominant isolate followed by Enterococci spp 4.5% and Coagulase negative staphylococci (CONS) 4.5% and S. pyogenes were 5.4%. Both Gram positive cocci and Gram negative bacilli can cause dia­betic foot infections and this study showed a preponderance of Gram negative bacilli. Early culture and sensitivity test of the bacterial isolates helps in guiding the treatment plan

scholarly journals Study on Bacteriological Profile and Antibiotic Susceptibility in Diabetic Foot Infection in a Teaching Hospital, Telangana

2021 ◽  
Vol 8 (20) ◽  
pp. 1538-1543
Author(s):  
Ritu Vaish
Keyword(s):  
Diabetic Foot ◽  
Antibiotic Susceptibility ◽  
Treatment Plan ◽  
Coagulase Negative Staphylococci ◽  
Cross Sectional ◽  
Female Ratio ◽  
Gram Negative ◽  
Diabetic Foot Infection ◽  
Bacteriological Profile ◽  
Culture And Sensitivity

BACKGROUND Diabetic foot is one of the most significant complications of diabetes. Chronic infections are caused by Enterococci, various Enterobacteriaceae obligate anaerobes, and Pseudomonas aeruginosa. We wanted to study bacteriological profile and antibiotic susceptibility in diabetic foot infection. METHODS A cross sectional study was done in 110 diabetic foot infection cases in the Department of Microbiology, Prathima Institute of Medical Sciences, Nagunuru, Karimnagar, Telangana. The grading of diabetic foot ulcers was done according to Wagner’s Classification system. The samples were collected from the exudates and ulcers. Gram staining was done and standard protocol for culture and sensitivity was followed for all the cases. RESULTS A total of 110 cases were studied. The patient age ranged from 35 to 75 years and the male to female ratio was 2:1. Out of 110 isolates, 72.7 % isolates were Gram negative bacilli with P. aeruginosa 31.8 % being the predominant followed by E. coli 27.2 %, K. pneumoniae 10 %, P. mirabilis 4.5 %, S. aureus 12.7 % was the predominant isolate followed by Enterococci spp 4.5 % and Coagulase negative staphylococci (CONS) 4.5 % and S. pyogenes were 5.4 %. CONCLUSIONS Both Gram positive cocci and Gram negative bacilli can cause diabetic foot infections and this study showed a preponderance of Gram negative bacilli. Early culture and sensitivity test of the bacterial isolates helps in guiding the treatment plan. KEYWORDS Bacteriological Profile, Diabetic Foot Infection

Bacterial Diversity, Antibiotic Resistance, and the Risk of Lower Limb Amputation in Younger and Older Individuals With Diabetic Foot Infection

2021 ◽  
pp. 153473462199229
Author(s):  
Stefan Dörr ◽  
Ann-Kathrin Holland-Letz ◽  
Gregor Weisser ◽  
Apostolos Chatzitomaris ◽  
Ralf Lobmann
Keyword(s):  
Bacterial Diversity ◽  
Diabetic Foot ◽  
Care Center ◽  
Bacterial Load ◽  
Limb Amputation ◽  
Older Individuals ◽  
Foot Care ◽  
Gram Positive ◽  
Gram Negative ◽  
Diabetic Foot Infection

Introduction A diabetic foot infection (DFI) contributes to high mortality and morbidity in diabetics due to its often rapid progressive and intricately treatable infection. DFIs are usually a polymicrobial infection and characterizing the entire bacterial load is still challenging. Prompt and effective treatment of DFI is nevertheless mandatory to safe limbs and lives. It is therefore crucial to know the local pathogen spectrum and its antibiotic susceptibility. Methods and Material For a 12-month period, we investigated 353 individuals with infected diabetic foot ulcer, their bacterial diversity, and antimicrobial susceptibility at fist-time visit in a Diabetic Foot Care Center in southern Germany. Results Cultures yielded 888 species, most of them gram-positive cocci (primary Staphylococcus aureus). The gram-negative sector was mainly formed by Pseudomonas aeruginosa and Enterobacteriacae. Because the prevalence of multiresistant species was surprisingly low (0.9% of isolated strains), we suggest penicillins with β-lactamase inhibitor in case of gram-positive–dominated infection or piperacillin/tazobactam or rather carbapenems with equal efficacy when gram-negative species are involved.

scholarly journals Prevalence of Peripheral Vascular Disease in Diabetic Foot Infections and its Effect on Management Outcome

2019 ◽  
Vol 38 (1) ◽  
pp. 12-17
Author(s):  
Farah Nobi ◽  
Syed Al Nahian ◽  
Afrin Sultana ◽  
Rokhsana Sarmin ◽  
Ayesha Rahman ◽  
...  
Keyword(s):  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Lower Limb ◽  
Diabetic Foot ◽  
Tertiary Care ◽  
Peripheral Vascular ◽  
Tertiary Care Centre ◽  
Term Care ◽  
Diabetic Foot Infection ◽  
Diabetic Foot Infections

Background: Foot infection is a common problem affecting diabetics. Ischemia is a major factor contributing to progress and morbidity of the disease. The prevalence of peripheral vascular disease is higher in diabetics with faster progression. Aim: This study aimed to observe the prevalence of peripheral vascular disease in patients with diabetic foot infections presenting to this tertiary care centre. Methods: This prospective observational study evaluated 250 patients with diabetic foot infection admitted to Ibrahim Medical College and BIRDEM General Hospital, Dhaka, from 1st January 2015 to 31st December 2015.Total 72 patients were selected for Duplex study of lower limb vessels, Ankle Brachial Pressure Index (ABPI) and Pulse oxymetrywhich established the diagnosis of peripheral vascular disease and all patients were treated according to the standard protocol. Results: Of the 72 patients peripheral vascular disease was found in 25 patients (34.7%) and majority of them (88%) had distal below the knee vessel stenosis. There was significant correlation with older age (75%) and history of tobacco use (64%). The clinical presentations and outcomes such as hospital stay, healing time, pain were worse in individuals with peripheral vascular compromise on Duplex study of lower limb vessels, ABPI and pulse oxymetry. Conclusion: In this study we observed that significant number of diabetics presenting with foot infections have underlying peripheral vascular disease .The patients might not all be symptomatic or show obvious signs of PVD but need to be investigated for the same. Early detection of peripheral vascular disease in patients presenting with diabetic foot infection, using Duplex study,ABPI and Pulse oxymetrywith routine clinical and laboratory assessment can be of great value in long term care of these individuals. J Bangladesh Coll Phys Surg 2020; 38(1): 12-17

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