Gd-Doped Superparamagnetic Magnetite Nanoparticles for Potential Cancer Theranostics

Nanomedicine is widely developed in recent years. In nanomedicine system, nanoscale and nanostructured functional materials are used to manipulate the human biology systems at the molecular level for cancer imaging and therapy. New nanostructure based functional materials consist of nanoscale liposomes, spheres, micelles, capsules, emulsion, suspension and phamacosomes. Several functional nanoparticles such as lipidbased and polymer-based materials are demonstrated to be drug delivery vehicles and imaging agents. These materials are biodegradable, biocompatible and have better biodistribution, lower side effect and lower toxicity. In addition, hybrids with these materials coating provide uniquely electrical, optical and magnetic properties. This review discusses the research on the applications of functional materials, especially nanoparticles as imaging contrast agents, cancer therapeutic agents and multi-functional agents and this review focused on the theranostic integration treatments on liver cancer and brain cancer.

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Solid Phase Extraction Based on Thiol Functionalized Magnetite Nanoparticles to Determination Some Heavy Metal Ions in Water Samples Using Atomic Absorption Spectrometry

Current Analytical Chemistry ◽

10.2174/1573411012666160504124118 ◽

2017 ◽

Vol 13 (2) ◽

pp. 174-180 ◽

Cited By ~ 2

Author(s):

Malihe Kazemi

Keyword(s):

Heavy Metal ◽

Solid Phase Extraction ◽

Atomic Absorption Spectrometry ◽

Atomic Absorption ◽

Magnetite Nanoparticles ◽

Water Samples ◽

Heavy Metal Ions ◽

Solid Phase ◽

Absorption Spectrometry ◽

Phase Extraction

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Polymer-Graphene Nanoassemblies and their Applications in Cancer Theranostics

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/1871520619666191028112258 ◽

2020 ◽

Vol 20 (11) ◽

pp. 1340-1351 ◽

Cited By ~ 1

Author(s):

Ponnurengam M. Sivakumar ◽

Matin Islami ◽

Ali Zarrabi ◽

Arezoo Khosravi ◽

Shohreh Peimanfard

Keyword(s):

Mechanical Stability ◽

Chemical Properties ◽

The Other ◽

Hydrophilic Polymer ◽

Two Dimensional ◽

Normal Tissues ◽

Physical Chemical ◽

Anti Cancer ◽

Good Biocompatibility ◽

Cancer Theranostics

Background and objective: Graphene-based nanomaterials have received increasing attention due to their unique physical-chemical properties including two-dimensional planar structure, large surface area, chemical and mechanical stability, superconductivity and good biocompatibility. On the other hand, graphene-based nanomaterials have been explored as theranostics agents, the combination of therapeutics and diagnostics. In recent years, grafting hydrophilic polymer moieties have been introduced as an efficient approach to improve the properties of graphene-based nanomaterials and obtain new nanoassemblies for cancer therapy. Methods and results: This review would illustrate biodistribution, cellular uptake and toxicity of polymergraphene nanoassemblies and summarize part of successes achieved in cancer treatment using such nanoassemblies. Conclusion: The observations showed successful targeting functionality of the polymer-GO conjugations and demonstrated a reduction of the side effects of anti-cancer drugs for normal tissues.

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Melanogenesis Exploitation and Melanoma Nanomedecine: Utilization of Melanogenesis Substrate, NPrCAP for Exploiting Melanoma-Targeting Drug and its Conjugation with Magnetite Nanoparticles for Developing Melanoma Chemo-Thermo-Immunotherapy

The Open Conference Proceedings Journal ◽

10.2174/2210289201102010005 ◽

2011 ◽

Vol 2 (1) ◽

pp. 5-16 ◽

Cited By ~ 1

Author(s):

K. Jimbow

Keyword(s):

Magnetite Nanoparticles

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