scholarly journals Acute and Chronic Effects of Hypobaric Exposure upon the Brain

Author(s):  
Paul Sherman ◽  
John Sladky
Impact ◽  
2020 ◽  
Vol 2020 (3) ◽  
pp. 63-65
Author(s):  
Tomomi Higashi

Talk to any allergy sufferer and they will tell you how awful it can be. Runny noses, itchy eyes, coughing and difficulties breathing. For many these symptoms rise only to the level of annoyance and can be avoided by steering clear of the source of their allergy. What many people don't realise though is that allergies can become a far more serious issue for a large segment of the population. Shortness of breath and difficulty breathing due to allergies bring many people to emergency rooms and these are just the acute symptoms. Along with the potential for an allergic attack during a windy or dusty day, researchers and medical professionals are beginning to recognise that there are chronic, long term effects associated with allergies. In order to mitigate both the acute and chronic effects of allergies a better understanding of how genetic factors combine with environmental conditions to produce the ranges of symptoms and effects of allergy suffers is needed. Professor Tomomi Higashi, from the Department of Hygiene at Kanazawa University in Japan, is an expert in this field and is currently working to improve treatment and prevention of allergic disease.


Circulation ◽  
1971 ◽  
Vol 43 (5s1) ◽  
Author(s):  
L. MAXIMILIAN BUJA ◽  
SIDNEY LEVITSKY ◽  
VICTOR J. FERRANS ◽  
SHERMAN G. SOUTHER ◽  
WILLIAM C. ROBERTS ◽  
...  

Hypertension ◽  
1997 ◽  
Vol 30 (3) ◽  
pp. 714-719 ◽  
Author(s):  
Gustavo José Justo Silva ◽  
Patricia Chakur Brum ◽  
Carlos Eduardo Negrão ◽  
Eduardo Moacyr Krieger

2020 ◽  
Vol 11 ◽  
Author(s):  
Adellah Sariah ◽  
Shuixia Guo ◽  
Jing Zuo ◽  
Weidan Pu ◽  
Haihong Liu ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maria Paola Tramonti Fantozzi ◽  
Giulia Lazzarini ◽  
Vincenzo De Cicco ◽  
Angela Briganti ◽  
Serena Argento ◽  
...  

AbstractTrigeminal input exerts acute and chronic effects on the brain, modulating cognitive functions. Here, new data from humans and animals suggest that these effects are caused by trigeminal influences on the Locus Coeruleus (LC). In humans subjects clenching with masseter asymmetric activity, occlusal correction improved cognition, alongside with reductions in pupil size and anisocoria, proxies of LC activity and asymmetry, respectively. Notably, reductions in pupil size at rest on the hypertonic side predicted cognitive improvements. In adult rats, a distal unilateral section of the trigeminal mandibular branch reduced, on the contralateral side, the expression of c-Fos (brainstem) and BDNF (brainstem, hippocampus, frontal cortex). This counterintuitive finding can be explained by the following model: teeth contact perception loss on the lesioned side results in an increased occlusal effort, which enhances afferent inputs from muscle spindles and posterior periodontal receptors, spared by the distal lesion. Such effort leads to a reduced engagement of the intact side, with a corresponding reduction in the afferent inputs to the LC and in c-Fos and BDNF gene expression. In conclusion, acute effects of malocclusion on performance seem mediated by the LC, which could also contribute to the chronic trophic dysfunction induced by loss of trigeminal input.


Author(s):  
Cristiéle da Silva Ribeiro ◽  
Matthias Schreiner ◽  
Carlos Arturo Navas Iannini ◽  
Aline Dal'Olio Gomes ◽  
Carlos Eduardo Tolussi ◽  
...  

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