scholarly journals Detection of Nutrient-Related SNP to Reveal Individual Malnutrition Risk

Malnutrition ◽  
2020 ◽  
Author(s):  
Junsheng Huo ◽  
Chunhong Zhang

Malnutrition is a result of complicated reasons from diet and food behavior and also related to genetic background which has been revealed by studies in recent decades. Traditionally, nutrition status are measured and expressed with indexes of anthropometric, diet survey, clinical symptom, biochemistry, behavior, etc. These measurement has been used in national nutrition monitoring, clinic nutrition therapy, mother and children nutrition care, nutrition intervention projects, and scientific studies. However, genetic and epigenetic information on nutrition explain malnutrition in a genetic view that would supply additional new theory and methodology for the growing requirement in terms of personalized and precise nutrition. In this chapter, an introduction on the detection of nutrient-related SNP to reveal individual malnutrition risk is discussed.

2008 ◽  
Vol 5 (1) ◽  
pp. 1
Author(s):  
Ika Yuliati C ◽  
I Made Alit Gunawan ◽  
R Dwi Budinigsari

Background: Medical nutrition therapy (MNT) is one of nutrition care models which focuses on integrated patient management involving active participation of doctors, nutritionists, nurses, and other professions within nutrition care team. An indicator of success in nutrition intervention is nutrition intake. Bekasi Municipal Hospital has not implemented integrated nutrition care within a team. The result of monitoring and evaluation during the first quarter of 2006 showed that average patient nutrition intake was only 65-70% (inadequate).Objective: To identify the influence of nutrition care implementation using MNT approach to nutrition intake and length of stay at Bekasi Municipal Hospital.Method: The study was quaci-experimental which used static-group comparison. Samples were patients hospitalized at internal medicine ward of class VIP, 1, 2, and 3. Data obtained consisted of conventional nutrition care and MNT, data of nutrition intake using Comstock visual and 24 hour recall methods. T-test and Mann Whitney statistical test were used to analyze the influence of types of nutrition care to nutrition intake.Results: Average percentage of total nutrition intake of hospital food and outside hospital food sample with MNT nutrition care was better than conventional nutrition care. Total nutrition intake was 91.71% for energy, 92.12% for protein, 111.83% for fat, and 85.41% for carbohydrate. The result was significant for energy intake (p<0.05). Nutrition intake of sample hospital was 86.08% for energy, 88.91% for protein, 108.55% for fat, and 78.91% for carbohydrate. Nutrition intake of outside hospital was 21.94% for energy, 13.77% for protein, 12.22% for fat, and 35.43% for carbohydrate. They were not significant statistically.Conclusion: There was difference in nutrition intake between samples with MNT and conventional nutrition care. Nutrition intake of samples with MNT was better than conventional nutrition care and statistically significant (p<0.05).


2010 ◽  
Vol 63 (11-12) ◽  
pp. 816-821
Author(s):  
Budimka Novakovic ◽  
Jelena Jovicic ◽  
Ljiljana Pavlovic-Trajkovic ◽  
Maja Grujicic ◽  
Ljilja Torovic ◽  
...  

Introduction. Diet has vital, preventive and therapeutic functions. Medical nutrition therapy is a part of the Standardized Nutrition Care Process integrated in health care systems. Material and methods. An overview of the Nutrition Care Process model and the application of nutrition guidelines based on literature, reports, documents and programmes of international health, food and physical activity authorities was done. Results. The Nutrition Care Process model requires registered dieticians, standardized terminology as well as nutrition diagnosis categorization. It consists of four distinct, but interrelated and connected steps: (a) nutrition assessment, (b) nutrition diagnosis, (c) nutrition intervention, and (d) nutrition monitoring and evaluation. An individual approach is essential for successful medical nutrition therapy. Nutrition guidelines facilitate the process of understanding and application of medical nutrition therapy. Conclusion. The Nutrition Care process provides dietetic professionals information on high-quality client nutrition care. The success of medical nutrition therapy rests not only upon the advice of the dietician, but also upon the client?s compliance.


2020 ◽  
pp. 1-25
Author(s):  
Yidi Wang ◽  
Bradley A. Feltham ◽  
Michael N. A. Eskin ◽  
Miyoung Suh

Abstract Maternal nutrition status plays an important role in the development of fetal alcohol spectrum disorders (FASD), but its direct evidence is lacking. This study compared a standard chow with a semi-purified energy dense (E-dense) diet on birth and metabolic outcomes in rats after ethanol (EtOH) consumption during pregnancy. Pregnant Sprague-Dawley rats were randomized into four groups: chow (n=6), chow+EtOH (20% v/v) (n=7), E-dense (n=6), and E-dense+EtOH (n=8). Birth outcomes including litter size, body and organ weights were collected. Metabolic parameters were measured in dams and pups at postnatal day (PD) 7. Maternal EtOH consumption decreased body weights (p <0.0001) and litter sizes (p <0.05) in chow-fed dams. At PD7, pups born to dams fed E-dense diet had higher body (p <0.002) and liver weights (p <0.0001). These pups also had higher plasma total cholesterol (p <0.0001), triacyclglycerol (p <0.003) and alanine aminotransferase (p <0.03) compared to those from chow-fed dams. Dams fed E-dense diet had higher plasma total- (p <0.0001) and HDL-cholesterol (p <0.0001) and lower glucose (p <0.0001). EtOH increased total cholesterol (p <0.03) and glucose (p <0.05) only in dams fed the E-dense diet. Maternal exposure to E-dense diet attenuated prenatal EtOH-induced weight loss and produced different metabolic outcomes in both dams and pups. While the long-lasting effects of these outcomes are unknown, this study highlights the importance of maternal diet quality for maternal health and infant growth, and suggests that maternal nutrition intervention may be a potential target for alleviating FASD.


Author(s):  
Mary Beth Arensberg ◽  
Beth Besecker ◽  
Laura Weldishofer ◽  
Susan Drawert

AbstractThe Oncology Care Model (OCM) is a US Centers for Medicare & Medicaid Services (CMS) specialty model implemented in 2016, to provide higher quality, more highly coordinated oncology care at the same or lower costs. Under the OCM, oncology clinics enter into payment arrangements that include financial and performance accountability for patients receiving chemotherapy treatment. In addition, OCM clinics commit to providing enhanced services to Medicare beneficiaries, including care coordination, navigation, and following national treatment guidelines. Nutrition is a component of best-practice cancer care, yet it may not be addressed by OCM providers even though up to 80% of patients with cancer develop malnutrition and poor nutrition has a profound impact on cancer treatment and survivorship. Only about half of US ambulatory oncology settings screen for malnutrition, registered dietitian nutritionists (RDNs) are not routinely employed by oncology clinics, and the medical nutrition therapy they provide is often not reimbursed. Thus, adequate nutrition care in US oncology clinics remains a gap area. Some oncology clinics are addressing this gap through implementation of nutrition-focused quality improvement programs (QIPs) but many are not. What is needed is a change of perspective. This paper outlines how and why quality nutrition care is integral to the OCM and can benefit patient health and provider outcomes.


Author(s):  
Eram Albajri ◽  
Manal Naseeb

The proposed case will discuss irritable bowel syndrome. Individualized medical nutrition therapy is critical in the disease management. In this case, the learner will be provided with details to conceptualize the case and will be able to conduct a comprehensive nutrition assessment to evaluate the nutritional status. After identifying and prioritizing nutrition problems, the learner will determine the nutrition diagnoses and write proper statements. Based on the collected data, the learner will develop a nutrition care plan with appropriate goals, interventions, and strategies for monitoring and evaluation. Unspecified-IBS encounter challenges with food as it triggers the symptoms. Thus, the learner will evaluate the nutrient composition of dietary history and provide a substitute considering individual tolerance and severity of the symptoms. In addition, FODMAP will be applied. It also teaches patients what foods or eating patterns would be best (or best to avoid) for their day-to-day activities through self-awareness of symptoms and dietary food log.


Author(s):  
Shoug Alashmali

This chapter will discuss a case of diarrhea/constipation. Diarrhea and constipation are functional bowel disorders (FBDs) of the mid or lower gastrointestinal (GI) tract. These FBDs result from intestinal motility dysfunction and/or changes in intestinal fluid absorption, which in turn leads to bloating, discomfort, and occasionally, abdominal pain. Certain dietary choices aggravate these conditions, leading to serious complications. Management of diarrhea/constipation usually requires the use of medications and/or lifestyle modifications. The presently discussed case involved factors that exacerbated the conditions of diarrhea/constipation. This case serves as an example of the role of medical nutrition therapy in managing FBDs (particularly diarrhea and constipation). Moreover, this case will allow the dietetic professional to assess the causes of diarrhea/constipation in order to plan for the nutrition intervention and educate the patient about the dietary manipulations required to reduce their symptoms.


Author(s):  
Albatool Abumunaser

This chapter will discuss a peptic ulcer disease (PUD) case. PUD is a common gastrointestinal tract disease (GIT) that affects the stomach and duodenum. It is characterized by deep lesions into the mucosal thickness. Various dietary and behavioral choices could aggravate the epigastric pain associated with PUD and interfere with the healing process leading to complications. Management of PUD includes medical treatment with medications along with behavioral and nutritional changes. This case presents a complication of PUD, and choices exacerbating the condition. It will also discuss the role of medical nutrition therapy in minimizing the symptoms and promoting ulcer healing. Additionally, it will allow the dietetic professional to methodically assess the elements in the case that are relevant for planning the nutrition intervention; in addition to, educating the patient about dietary modifications to improve the patient's quality of life.


Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3403
Author(s):  
Julie Richards ◽  
Mary Beth Arensberg ◽  
Sara Thomas ◽  
Kirk W. Kerr ◽  
Refaat Hegazi ◽  
...  

Malnutrition is prevalent among oncology patients and can adversely affect clinical outcomes, prognosis, quality of life, and survival. This review evaluates current trends in the literature and reported evidence around the timing and impact of specific nutrition interventions in oncology patients undergoing active cancer treatment. Previous research studies (published 1 January 2010–1 April 2020) were identified and selected using predefined search strategy and selection criteria. In total, 15 articles met inclusion criteria and 12/15 articles provided an early nutrition intervention. Identified studies examined the impacts of nutrition interventions (nutrition counseling, oral nutrition supplements, or combination of both) on a variety of cancer diagnoses. Nutrition interventions were found to improve body weight and body mass index, nutrition status, protein and energy intake, quality of life, and response to cancer treatments. However, the impacts of nutrition interventions on body composition, functional status, complications, unplanned hospital readmissions, and mortality and survival were inconclusive, mainly due to the limited number of studies evaluating these outcomes. Early nutrition interventions were found to improve health and nutrition outcomes in oncology patients. Future research is needed to further evaluate the impacts of early nutrition interventions on patients’ outcomes and explore the optimal duration and timing of nutrition interventions.


2015 ◽  
Vol 7 (3) ◽  
pp. 244 ◽  
Author(s):  
Jennifer Crowley ◽  
Lauren Ball ◽  
Dug Yeo Han ◽  
Anne-Thea McGill ◽  
Bruce Arroll ◽  
...  

INTRODUCTION: Improvements in individuals' nutrition behaviour can improve risk factors and outcomes associated with lifestyle-related chronic diseases. AIM: This study describes and compares New Zealand medical students, general practice registrars and general practitioners' (GPs') attitudes towards incorporating nutrition care into practice, and self-perceived skills in providing nutrition care. METHODS: A total of 183 New Zealand medical students, 51 general practice registrars and 57 GPs completed a 60-item questionnaire investigating attitudes towards incorporating nutrition care into practice and self-perceived skills in providing nutrition care. Items were scored using a 5-point Likert scale. Factor analysis was conducted to group questionnaire items and a generalised linear model compared differences between medical students, general practice registrars and GPs. RESULTS: All groups indicated that incorporating nutrition care into practice is important. GPs displayed more positive attitudes than students towards incorporating nutrition in routine care (p<0.0001) and performing nutrition recommendations (p<0.0001). General practice registrars were more positive than students towards performing nutrition recommendations (p=0.004), specified practices (p=0.037), and eliciting behaviour change (p=0.024). All groups displayed moderate confidence towards providing nutrition care. GPs were more confident than students in areas relating to wellness and disease (p<0.0001); macronutrients (p=0.030); micronutrients (p=0.010); and women, infants and children (p<0.0001). DISCUSSION: New Zealand medical students, general practice registrars and GPs have positive attitudes and moderate confidence towards incorporating nutrition care into practice. It is possible that GPs' experience providing nutrition care contributes to greater confidence. Strategies to facilitate medical students developing confidence in providing nutrition care are warranted. KEYWORDS: General practitioner; health knowledge, attitudes, practice; medical education; nutrition therapy


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