scholarly journals The Effect of Resistance Training and Vitamin D on Leptin and HDL-C in Overweight Women

Author(s):  
Maryam Najafi ◽  
Hoseyn Fatolahi

Background: Exercise training and vitamin D consumption are separately reported to be effective on improving health. However, the simultaneous effect of resistance training and vitamin D is not clear yet. However, there is no information available on the resistance training and the amount of vitamin D prescription. In addition, it is important to examine this issue in women who are known as an active and effective part of society. Methods: The participants (n = 40) of this study were randomly divided into four groups as follows: (1) placebo, (2) resistance training, (3) vitamin D, and (4) resistance training + vitamin D. In this study, interventions were performed for an 8-week period (3 D/W) consisting of resistance training protocol (60% 1-RM) and daily consumption of vitamin D (1000 IU). Anthropometric and laboratory measurements were collected 48 hours before and after the intervention. Results: Changes in HDL-C (P = 0.001, F = 6.3), total cholesterol (P = 0.001, F = 7.8), and leptin concentration (P = 0.001, F = 11.4) were significant. Accordingly, these changes in the study variables showed a better improvement in the resistance training + vitamin D group compared to the other groups (P = 0.001). Conclusions: Probably the most important factor for the observed changes was the reduction of adipose tissue caused by resistance training, as well as the enhancement of signaling pathways resulting from the consumption of vitamin D. However, maintaining muscle tissue caused by resistance training can be effective. Moreover, HDL change due to resistance training and its effect on reverse cholesterol transport may occur faster than LDL-C changes. Also, the improvement in LDL-C appears in response to longer periods of exercise along with drug therapy.

2020 ◽  
Vol 125 (2) ◽  
pp. 139-146
Author(s):  
N. Al-Bayyari ◽  
R. Hailat ◽  
H. Subih ◽  
H. Alkhalidy ◽  
A. Eaton

AbstractThe objective of this study was to evaluate the effect of vitamin D3 on total homocysteine (tHcy) and C-reactive protein (CRP) levels and liver and kidney function tests in overweight women with vitamin D deficiency. Therefore, a randomised, double-blind placebo, controlled clinical trial was conducted on 100 eligible women. Subjects were randomly divided into two groups: the placebo (n 50) and the vitamin D (n 50) which received 1250 µg vitamin D3 per week for 2 months. The participants’ 25-hydroxyvitamin D (25(OH)D), tHcy, CRP, alanine aminotransferase (ALT), aspartate aminotransferase (AST), urea, creatinine and estimated glomerular filtration rate (eGFR) were measured and compared before and after treatment. Results showed that the tHcy, CRP, AST, ALT and eGFR levels after the 2nd month of vitamin D3 intervention were significantly (P < 0·001) decreased and the 25(OH)D, urea and creatinine levels were significantly (P < 0·001) increased in the treatment group. In the placebo group, no significant changes were identified throughout the follow-up period. In conclusion, vitamin D3 intervention with a treatment dose of 1250 µg/week for at least 2 months may help in lowering Hcy and CRP levels and may improve liver function tests, which in turn might help in minimising the risk of CVD and liver diseases among overweight women but negatively affect kidney function.


Author(s):  
Kimberly M. White ◽  
Stephanie J. Bauer ◽  
Kristopher K. Hartz ◽  
Monika Baldridge

Introduction:Resistance training is an effective method to decrease body fat (BF) and increase fat-free mass (FFM) and fat oxidation (FO). Dairy foods containing calcium and vitamin D might enhance these benefits. This study investigated the combined effects of habitual yogurt consumption and resistance training on body composition and metabolism.Methods:Untrained women (N = 35) participated in an 8-wk resistance-training program. The yogurt group (Y) consumed 3 servings of yogurt containing vitamin D per day, and the control groups maintained their baseline lowdairy-calcium diet. Postexercise, Y consumed 1 of the 3 servings/d fat-free yogurt, the protein group consumed an isocaloric product without calcium or vitamin D, and the carbohydrate group consumed an isocaloric product without protein. Strength, body composition, fasted resting metabolic rate (RMR) and FO, and serum 25-hydroxyvitamin D were measured before and after training.Results:Calories (kcal · kg−1 · d−1) and protein (g · kg−1 · d−1) significantly increased from baseline for Y. FFM increased (main effect p = .002) and %BF decreased (main effect .02) for all groups with training, but Group × Time interactions were not observed. RMR and FO did not change with training for any group.Conclusion:Habitual consumption of yogurt during resistance training did not augment changes in body composition compared with a low-dairy diet. Y decreased %BF as a result of training, however, even with increased calorie consumption.


2019 ◽  
Vol 9 (o3) ◽  
Author(s):  
Suaad Muhssen Ghazi ◽  
Fatin Shallal Farhan

Vitamin D deficiency is common in women with polycystic ovarian syndrome. Vitamin D plays an important physiologic role in reproductive functions of ovarian follicular development and luteinization through altering anti-müllerian hormone signaling, follicular stimulating hormone activity and progesterone production in human granulose cells. Vitamin D is precipitated in adipose fat tissues, making it notable to be used for the body as a result; obese people with high body mass index are already highly expected to have low levels of serum vitamin D.


Author(s):  
Sanjeeva Kumar Goud T ◽  
Rahul Kunkulol

The present study was aimed to study the effect of Sublingual Vitamin D3 on Serum Vitamin D level in Vitamin D deficiency patients. This was a cross-sectional and interventional study. All the Vitamin D deficiency patients of age 18-60years and either gender, willing to participate in the study were included. Patients who had greater than 20 ng/ml were excluded from the study. The total number of participants in our study was 200, out of these 111 males and 89 females, the mean age in our study was 51.07 ± 7.39Yrs. All volunteers were given sublingual vitamin D3 (60,000IU) in six doses every fifteen days of follow up for 3 months. The subject’s serum 25(OH)D levels were estimated before and after the treatment of sublingual vitamin D3. There was a statistically significant difference in serum vitamin D3 level before 16.61±6.71 ng/ml and after 35.80±7.80 ng/ml after treatment with Sublingual Vitamin D3. Six doses of 60,000IU of Vitamin D3 sublingual route having improved the role of serum 25(OH)D levels in the treatment of Vitamin D3 deficiency patients.Keywords: Vitamin D3; Sublingual route


Author(s):  
Natércia Neves Marques de Queiroz ◽  
Franciane Trindade Cunha de Melo ◽  
Fabrício de Souza Resende ◽  
Luísa Corrêa Janaú ◽  
Norberto Jorge Kzan de Souza Neto ◽  
...  

Background: Vitamin D (VD) deficiency has been related to several endocrine metabolic and cardiovascular diseases. Effect of VD supplementation on blood pressure (BP) in patients with diabetes is controversial. Objective: The aim of this study was to evaluate high-dose vitamin D supplementation effects on blood pressure of normotensive type 1 diabetes mellitus (T1DM) patients by 24-hour ambulatory blood pressure monitoring (ABPM). Methods: We performed a clinical trial including 35 T1DM normotensive patients, who received doses of 4,000 or 10,000 IU/day of cholecalciferol for 12 weeks according to previous VD levels. They underwent 24-hour ABPM, along with glycated hemoglobin, creatine, lipids profile and PCRus dosage before and after VD supplementation. Results and discussion: We found an expressive reduction of systolic and diastolic morning blood pressures (117±14 vs 112±14, p<0,05; 74±9 vs 70±10 mmHg, p<0,05, respectively) with no changes in other pressoric markers. Besides, we noticed a relation between levels of VD after supplementation and diastolic morning blood pressure (r= -0,4; p<0.05). Conclusion: Our study suggests an association between supplementation of high doses of vitamin D and the reduction of morning blood pressure in normotensive T1DM patients.


1995 ◽  
Vol 15 (5) ◽  
pp. 691-703 ◽  
Author(s):  
Arnold von Eckardstein ◽  
Yadong Huang ◽  
Shili Wu ◽  
Harald Funke ◽  
Giorgio Noseda ◽  
...  

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