scholarly journals Patellofemoral Morphology and Imaging Features of Patellar Tumors and Tumor-Like Lesions

2020 ◽  
Vol 17 (4) ◽  
Author(s):  
Tian-Hao Wu ◽  
Shu-Man Han ◽  
Tao Sun ◽  
Lei Cao ◽  
Yun-Heng Shi ◽  
...  
Keyword(s):  
Giant Cell ◽  
Patellofemoral Joint ◽  
Malignant Tumors ◽  
Bone Cyst ◽  
Bone Destruction ◽  
Control Group ◽  
Imaging Features ◽  
Benign Lesions ◽  
Joint Parameters ◽  
Tumor Like Lesions

Background: The patellofemoral joint parameters and imaging presentations of patellar tumors and tumor-like lesions are not clear. Objectives: The aim of this case-control study was to investigate patellofemoral joint parameters, clinical data and findings in patients with patellar tumors and tumor-like lesions. Patients and Methods: Twenty-nine patients with patellar diseases were enrolled. Morphological measurement was performed and analyzed in fourteen patients with patellar tumors (tumor group) and another fifteen patients without patellar diseases (control) who had complete computed tomography data as the control group. Results: Among 29 patients, there were twenty benign lesions (69.0%) and nine malignant tumors (31.0%). Benign lesions included chondroblastoma in nine patients (31.0%), giant cell tumor of bone in four (13.8%), chondroma in one (3.4%), hemangioma in one (3.4%), parosteal lipoma in one (3.4%), bone cyst in two (6.8%), aneurysmal bone cyst in one (3.4%), and fibrous dysplasia in one (3.4%). Malignant tumors were bone metastasis in four patients (13.8%), osteosarcoma in three (10.3%) including common osteosarcoma in two and well-differentiated osteosarcoma in the remaining one, chondrosarcoma in one (3.4%) and hemangiopericytoma in one (3.4%) patient. Chondroblastomas, giant cell tumors and fibrous dysplasia showed findings of expansile bone destruction lesions in imaging. Malignant tumors had bone destruction with ill-defined margins. The femoral trochlear angle was significantly greater in the tumor than the control group (P < 0.001, 159.19º ± 9.42º vs. 135.00º ± 5.50º), whereas the lateral pulley inclination (P = 0.01, 14.69º ± 8.91º vs. 20.73º ± 3.51º) and trochlear depth (P < 0.001, 3.10 ± 1.79 vs. 6.67 ± 1.26 mm) were significantly smaller in the tumor than the control group. Conclusion: The patellar tumors are mainly benign and rarely malignant. Comprehensive understanding of the distribution, incidence and imaging features of patellar tumors and patellofemoral morphological parameters can improve the diagnosis accuracy.

scholarly journals Clinical and Imaging Analysis of Primary Tumors of the Clavicle

2020 ◽  
Vol 17 (3) ◽  
Author(s):  
Bao-Hai Yu ◽  
Shu-Man Han ◽  
Tao Sun ◽  
Lei Cao ◽  
Hui-Zhao Wu ◽  
...  
Keyword(s):  
Malignant Tumors ◽  
Eosinophilic Granuloma ◽  
Bone Cyst ◽  
Bone Destruction ◽  
Benign Tumors ◽  
Imaging Features ◽  
Imaging Data ◽  
Primary Tumors ◽  
Tumor Like Lesions ◽  
Age Range

Background: The clinical and imaging presentations of primary tumors and tumor-like lesions in the clavicle are not clear. Objectives: To investigate the clinical and imaging presentations of primary tumors and tumor-like lesions in the clavicle for better diagnosis. Patients and Methods: Patients with clavicular diseases between 1963 and 2018 confirmed by pathology who had plain radiography, computed tomography (CT) scan and magnetic resonance imaging were enrolled. The age, sex, imaging data, radiological signs and location of the tumor at the clavicle of patients were analyzed and compared. Results: Eighty-one patients with clavicular diseases were identified including 49 males and 32 females with an age range of 2 - 76 years (mean, 42.6). There were malignant tumors in 50 cases (61.7%), intermediate in 12 (14.8%), and benign in 19 cases (23.5%). Malignant tumors included metastatic tumors in 31 cases (38.3%), plasma-cell myeloma in ten (12.3%), and osteosarcoma in four (4.9%). The intermediate bone tumors were mainly eosinophilic granuloma in six cases (7.4%), and aneurysmal bone cyst in three (3.7%). Benign tumors were mainly osteochondroma (6.2%), bone cyst (3.7%), and chondroma (3.7%). Malignant tumors had bone destruction, periosteal reaction, ill-defined margins and soft tissue masses. Benign tumors and tumor-like lesions had well-defined margins. Conclusion: Many tumors may occur at the clavicle with more malignant than benign tumors with no specific imaging features in most lesions. A lesion near the sternal end with atypical benign imaging features should be considered as malignant.

Primary clinical study of radiomics for diagnosing simple bone cyst of the jaw

2021 ◽  
pp. 20200384
Author(s):  
Zhe-Yi Jiang ◽  
Tian-Jun Lan ◽  
Wei-Xin Cai ◽  
Qian Tao
Keyword(s):  
Bone Cyst ◽  
Maxillofacial Surgery ◽  
Correlation Coefficients ◽  
Texture Features ◽  
Image Features ◽  
Control Group ◽  
Imaging Features ◽  
Bone Cysts ◽  
Difference Matrix ◽  
Occurrence Matrix

Objective: To screen the radiomic features of simple bone cysts of the jaws and explore the potential application of radiomics in pre-operative diagnosis of jaw simple bone cysts. Methods: The investigators designed and implemented a case–control study. 19 patients with simple bone cysts who were admitted to the Department of Maxillofacial Surgery, Sun Yat-sen University Affiliated Stomatology Hospital from 2013 to 2019 were included in this study. Their clinical data and cone-beam computed tomography (CBCT) images were examined. The control group consisted of patients with odontogenic keratocyst. CBCT imaging features were analyzed and compared between the patient and control groups. Results: Overall, 10,323 image features were extracted through feature analysis. A subset of 25 radiomic features obtained after feature selection were analyzed further. These 25 features were significantly different between the 2 groups (p < 0.05). The absolute value of correlation coefficient was 0.487–0.775. Gray-level co-occurrence matrix (GLCM) contrast, neighborhood gray tone difference matrix (NGTDM) contrast, and GLCM variance were the features with the highest correlation coefficients. Conclusions: Pre-operative radiomics analysis showed the differences between simple bone cysts and odontogenic keratocysts, can help to diagnose simple bone cysts. Three specific texture features—GLCM contrast, NGTDM contrast, and GLCM variance—may be the characteristic imaging features of simple bone cysts of the jaw.

scholarly journals Imaging Review of Skeletal Tumors of the Pelvis Malignant Tumors and Tumor Mimics

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Gandikota Girish ◽  
Karen Finlay ◽  
David Fessell ◽  
Deepa Pai ◽  
Qian Dong ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Malignant Tumors ◽  
Clinical History ◽  
Imaging Features ◽  
Resonance Imaging ◽  
Benign Lesions ◽  
Plain Films ◽  
Malignant Lesions ◽  
Pelvic Lesions

Malignant lesions of the pelvis are not uncommon and need to be differentiated from benign lesions and tumor mimics. Appearances are sometimes nonspecific leading to consideration of a broad differential diagnosis. Clinical history, anatomic location, and imaging characterization can help narrow the differential diagnosis. The focus of this paper is to demonstrate the imaging features and the role of plain films, computed tomography, and magnetic resonance imaging for detecting and characterizing malignant osseous pelvic lesions and their common mimics.

Clinical and imaging features of tumors in the scapula

2021 ◽  
Vol 17 ◽  
Author(s):  
Yan Song ◽  
Jie Liu ◽  
Lei Cao ◽  
Bao-Hai Yu ◽  
Tao Sun ◽  
...  
Keyword(s):  
Malignant Tumors ◽  
Eosinophilic Granuloma ◽  
Central Area ◽  
Benign Tumors ◽  
Imaging Features ◽  
Metastatic Tumors ◽  
Cortical Destruction ◽  
Flat Bone ◽  
Tumor Like Lesions ◽  
Scapular Body

Background: Scapula is a small irregular-shaped flat bone, which may suffer from a variety of tumors or tumor-like lesions. Because the imaging manifestations are complex and changeable, correct imaging diagnosis is difficult. Introduction: At present, there are few related radiology literatures, and it is necessary to fully analyze the imaging signs of different types of benign and malignant tumors in scapula to guide clinical treatment. This study was to investigate clinical and imaging presentations of tumors and tumor-like lesions in the scapula so as to increase the diagnostic accuracy of diseases in the scapula. Methods: Patients with scapular tumors confirmed by pathology were enrolled. The imaging and clinical data were analyzed. Result: Among 108 patients, benign tumors were in 53 (49.1%) cases, intermediate in seven (6.5%), and malignant in 48 (44.4%) involving 16 diseases. Osteochondroma was the first benign tumors in 45 cases accounting for 84.9% of all benign scapular tumors followed by chondroma in four cases (7.5%). The intermediate tumors were mainly eosinophilic granuloma in four cases. Metastatic tumors were the commonest malignant tumor (27 cases or 56.2% of all malignant tumors), followed by chondrosarcoma (in 13 cases). Except for the one case of chondroblastoma in which the lesion involved the glenoid cavity, all the other cartilaginous tumors were located in the scapular body and processes. The type of lesions in the bony processes is the same as in the scapular body, the common lesions in the central area of body were malignant tumors, and the commonest lesions in the glenoid area were metastasis. Common imaging features of malignant scapular tumors were ill-defined margins, cortical destruction and soft tissue involvement. The imaging features of chondrosarcoma lack specificity except calcification. Benign lesions usually had clear boundary and marginal sclerosis. Conclusion : A wide variety of benign and malignant tumors may occur in the scapula with mostly cartilaginous and metastatic tumors, and the location and distribution of lesions are similar in the scapula to those in the long bones.

Aneurysmal Bone Cyst and Giant Cell Tumor of the Foot

1996 ◽  
Vol 17 (8) ◽  
pp. 487-495 ◽  
Author(s):  
Roberto Casadei ◽  
Pietro Ruggieri ◽  
Manuela Moscato ◽  
Andrea Ferraro ◽  
Piero Picci
Keyword(s):  
Giant Cell ◽  
Bone Cyst ◽  
Bone Destruction ◽  
Lytic Lesion ◽  
Joint Involvement ◽  
X Rays ◽  
Giant Cell Tumors ◽  
Pathologic Fractures ◽  
Tarsal Bones ◽  
Aneurysmal Bone Cysts

From 1950 to 1994, 257 cases of benign bone tumors of the foot were treated at the Bone Tumor Center of the Rizzoli Institute. Aneurysmal bone cysts (ABC) and giant cell tumors (GCT) are rare and often they are misdiagnosed. To define the clinical and radiographic features useful for diagnosis, x-rays of 24 ABCs and 21 GCTs of the foot were reviewed. Adding our series to the cases reported in the literature, the only important clinical data that emerged was the average age of patients affected by ABC and GCT (15 and 27 years, respectively). ABCs localized in small tarsal bones were rare (6%), whereas 19% of GCTs were found in this site. The eccentric, round shape of a lytic lesion was more characteristic of GCT. An aggressive pattern of radiographic bone destruction was observed more frequently in GCT than in ABC ( P = 0.01). Septation was seen in both tumors. Typical of ABC was a sharp and trabeculated margin, whereas GCT had an ill-defined edge with normal cancellous bone ( P = 0.007). The growth of ABCs often expanded the cortex, while GCTs eroded, thinned, and broke the cortical bone ( P = 0.001). A saucerized cortex was observed only in ABCs. A bony shell was more characteristic of ABC than of GCT ( P = 0.002). Pathologic fractures (67%) and joint involvement, evaluated by computed tomography and magnetic resonance imaging (83%), were more frequent in GCTs, whereas fluid levels were more frequently observed in ABCs (47%). The majority of the tumors were stage 2, but GCTs represented 70% of stage 3 aggressive lesions.

scholarly journals The Diagnosis of Iliac Bone Destruction in Children: 22 Cases from Two Centres

2016 ◽  
Vol 2016 ◽  
pp. 1-6
Author(s):  
Xiangshui Sun ◽  
Yue Lou ◽  
Xiaodong Wang
Keyword(s):  
Clinical Features ◽  
Eosinophilic Granuloma ◽  
Correct Diagnosis ◽  
Bone Cyst ◽  
Bone Destruction ◽  
Iliac Bone ◽  
Histopathological Diagnosis ◽  
Imaging Features ◽  
Imaging Data ◽  
Tissue Mass

Iliac bone destruction in children is uncommon and presents various imaging features. Correct diagnosis based on clinical and imaging features is difficult. This research aimed to retrospectively explore the clinical features, imaging, and histopathological diagnosis of children with iliac bone destruction. A total of 22 children with iliac bone destruction were enrolled in this retrospective analysis from two children’s hospitals during July 2007 to April 2015. Clinical features, imaging, and histopathological findings were analysed. The mode of iliac bone destruction, lesion structure, and the relationship between the range of soft tissue mass and cortical destruction were determined based on imaging data. The data were analysed using descriptive methods. Of the iliac bone destruction cases, eight cases were neuroblastoma iliac bone metastasis, seven cases were bone eosinophilic granuloma, two cases were Ewing’s sarcoma, two cases were osteomyelitis, one case was bone cyst, one case was bone fibrous dysplasia, and one case was non-Hodgkin’s lymphoma. Iliac bone destruction varies widely in children. Metastatic neuroblastoma and eosinophilic granuloma are the most commonly involved childhood tumours.

scholarly journals Radiological features of central giant cell granuloma: comparative study of 7 cases and literature review

2021 ◽  
pp. 20200429
Author(s):  
Samip Shrestha ◽  
Jia Zhang ◽  
Jun Yan ◽  
Xiaomin Zeng ◽  
Xiaoyong Peng ◽  
...  
Keyword(s):  
Giant Cell ◽  
Clinical Features ◽  
Bone Destruction ◽  
Cystic Degeneration ◽  
Contrast Study ◽  
Imaging Features ◽  
Giant Cell Granuloma ◽  
Central Giant Cell Granuloma ◽  
Cortical Thinning ◽  
Mri Features

Objective: To review and analyze the clinical and imaging features of central giant cell granuloma patients and to review the relevant literatures for the diagnosis and clinical manifestation of central giant cell granuloma. Methods: Seven cases of central giant cell granuloma were retrospectively selected for the study, all of which were confirmed by pathology and had relevant imaging investigations. All seven cases had undergone CT scan, three cases had undergone MRI scan. Detailed clinical features were compared along with the imaging findings and analysis was done on the basis of their presentation and imaging features. Results: The clinical features, radiologic features were varied according to the site of the lesion. CT features include unevenly dense expansile mass causing bone destruction and cortical thinning. While MRI features with low to iso-intensity in T1- and T2 weighted images. There may be presence of cystic degeneration, hemorrhage or hemosiderin deposits or osteoid formation, which can cause T1 and T2 signal changes. On contrast study, the lesion doesn’t enhance but periphery may enhance mildly. Conclusion: Unevenly dense expansile mass with bone destruction and cortical thinning with low to iso-intensity in T1 weighted and T2 weighted images and mildly enhance peripherally, Central giant cell granuloma should be considered.

scholarly journals Radiological features of Central Giant Cell Granuloma: Comparative study of 7 case reports and literature review

2020 ◽  
Author(s):  
Samip Shrestha ◽  
Jia Zhang ◽  
Jun Yan ◽  
Xiaomin Zeng ◽  
Xiaoyong Peng ◽  
...  
Keyword(s):  
Giant Cell ◽  
Clinical Features ◽  
Bone Destruction ◽  
Cystic Degeneration ◽  
Contrast Study ◽  
Imaging Features ◽  
Giant Cell Granuloma ◽  
Central Giant Cell Granuloma ◽  
Cortical Thinning ◽  
T2 Weighted Images

Abstract Background: To review and analyze the clinical and imaging features of central giant cell granuloma patients and to review the relevant literatures for the diagnosis and clinical manifestation of central giant cell granuloma.Methods: 7 cases of central giant cell granuloma were retrospectively selected for the study all of which were confirmed by pathology and had relevant imaging investigations. All 7 cases had undergone CT scan, 3 cases had undergone MRI scan. Detailed clinical features were compared along with the imaging findings and analysis was done on the basis of their presentation and imaging features.Results: The clinical features, radiologic features were varied according to the site of the lesion. CT features include unevenly dense expansile mass causing bone destruction and cortical thinning. While MRI features with low to iso-intensity in T1 weighted and T2 weighted images. There may be presence of cystic degeneration, hemorrhage or hemosiderin deposits or osteoid formation, which can cause T1 and T2 signal changes. On contrast study, the lesion doesn’t enhance but periphery may enhance mildly. Conclusion: Unevenly dense expansile mass with bone destruction and cortical thinning with low to iso-intensity in T1 weighted and T2 weighted images and mildly enhance peripherally, CGCG should be considered.

scholarly journals Incidence of bone tumors and tumor like lesions at a tertiary centre - a study of 64 cases

2018 ◽  
Vol 6 (2) ◽  
pp. 533
Author(s):  
Nidhi Verma ◽  
Amit Tyagi ◽  
Preeti Singh ◽  
Meenakshi Tyagi ◽  
Monika Rathi ◽  
...  
Keyword(s):  
Bone Tumors ◽  
Malignant Tumors ◽  
Bone Cyst ◽  
Tertiary Care ◽  
Tertiary Care Centre ◽  
Diagnostic Modality ◽  
Female Ratio ◽  
Primary Bone Tumors ◽  
Tumor Dissemination ◽  
Tumor Like Lesions

Background: Primary bone tumors are uncommon lesions constituting less than 1% of all cancers. Although open biopsy has high accuracy, it increases risk of tumor dissemination in patients with highly malignant tumors. FNAC eliminates the complications that may occur in surgical procedures and also gives quick results. This study was conducted to determine the spectrum and demographic characteristics of bone tumors and tumor like lesions at a tertiary care centre in western Uttar Pradesh and also to assess the role of FNAC in their diagnosis.Methods: This is a three-year, retrospective as well as a prospective study done on a total of 64 cases. All the cases were subjected to detailed history, physical examination and radiological investigations. FNAC smears were stained with Giemsa and Papanicolaou stain. H and E staining was done for histopathology.Results: Mean age affected was 26 years. Male-female ratio was 2.8:1. Out of total 64 cases of bone tumors and tumor like lesions, maximum was chondrogenic tumors (17; 26.56%), followed by osteogenic tumors (15; 23.44%). Osteochondroma (08; 47.06%), Osteosarcoma (07; 46.66%) and Aneurysmal bone cyst (04; 50.0%) were the most common chondrogenic tumor, osteogenic tumor and tumor like lesion respectively. The most common bone affected was tibia (16; 25.0%), followed by femur (15; 23.4%). Sensitivity and specificity of FNAC as a diagnostic modality were 90.0% and 91.67% respectively.Conclusions: A good correlation is observed between cytological and histological diagnoses which implies that FNAC can be used as a preliminary diagnostic approach to bone tumors, although histopathology remains the gold standard.

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