scholarly journals Comparison Quality of Life and Emotional Processing among Patients with Major Thalassemia, Type 2 Diabetes Mellitus, and Healthy People

2020 ◽  
Vol 9 (3) ◽  
Author(s):  
Fatemeh Pourmohammad Fahreh ◽  
Mahmoud Shirazi

Objectives: This study aimed at comparing emotional processing and quality of life among patients with major thalassemia, type 2 diabetes mellitus, and healthy individuals. Methods: The present causal-comparative study was conducted on patients with thalassemia, type 2 diabetes mellitus, and healthy people in Saravan City in 2017. In this study, the available sampling method was conducted and 153 individuals (major thalassemia = 53, type 2 diabetes mellitus = 50, and healthy people = 50) were selected. Later, emotional processing and quality of life questionnaires were distributed among the participants. The data were analyzed using multivariate analysis of variance and Tukey post hoc test by running SPSS version 23. Results: In the thalassemia group, the mean score of emotional processing was higher than the other two groups; whereas, the mean score of the quality of life was lower compared with the other study groups. The three groups were significantly different in terms of emotional processing and the quality of life. The paired comparison between the groups showed that the signs of unprocessed emotion components of emotional processing were lower in the healthy group compared with the two patients’ groups. However, among the components of the quality of life, the mean scores of personal benefit, relationships, and environmental factors were higher among the healthy group. Conclusions: Chronic diseases affect emotional processing and the individuals’ quality of life. Therefore, we recommend to health centers to conduct comprehensive and preventive programs to improve participants’ mental health.

2021 ◽  
Vol 1 (2) ◽  
pp. 79-86
Author(s):  
Nazmi Liana Azmi ◽  
Nurul Aida Md Rosly ◽  
Hock Chun Tang ◽  
Anis Fariha Che Darof ◽  
Nor Dini Zuki

Introduction: Previous studies have reported the relationship between medication adherence and quality of life are interrelated. However, many of the results were found to be conflicting. This study aimed to assess the level and association of medication adherence and quality of life among type 2 diabetes mellitus patients in Raja Perempuan Zainab II Hospital, Kelantan, Malaysia. Materials and methods: A cross-sectional survey was conducted among adult type 2 diabetes mellitus patients on treatment for over 1 year using convenience sampling at outpatient.  Medication Compliance Questionnaire (MCQ) and revised Diabetes Quality of Life Questionnaire (DQOL) instrument were self-administered to eligible subjects. Data were analysed using GNU PSPP version 0.8.5 and reported for descriptive statistics as well as correlation of both parameters. Results: A total of 200 patients were recruited and they were mostly at the age of 40 to 60 years old. The mean (SD) score for MCQ was 26.0 (1.6) with the majority of them were non-adherent (55.0%, n=110). The mean (SD) score for overall revised DQOL instrument was 25.5 (8.9) while each domain of “satisfaction”, “impact” and “worry” had mean (SD) scores of 12.0 (5.0), 7.7 (3.4) and 5.9 (2.7), respectively. The scores obtained were only approximately half of the possible range of scores for QoL. There was no significant correlation between total score of medication adherence and quality of life when tested using Pearson’s correlation (r=-0.083, p=0.240). Independent t-test also demonstrated no significant relationship between medication adherence status and quality of life (p=0.883). Conclusion: Type 2 diabetes mellitus patients in our setting had unsatisfactory adherence but exhibited acceptable quality of life. We observed that both variables were not associated with one another. Further research is warranted to identify potential factors affecting non-adherence to medication.


2019 ◽  
Vol 7 (8) ◽  
pp. 1401-1405 ◽  
Author(s):  
Shofian Syarifuddin ◽  
Azizah Nasution ◽  
Aminah Dalimunthe ◽  
Khairunnisa

AIM: To analyse the characteristics, and analyse the impact of pharmacist intervention on quality of life (QOL) outpatients with type 2 diabetes mellitus (T2DM). METHODS: This six-month analytical cohort study was conducted by assessing the patients’ characteristics and their quality of life by distributing a questionnaire, and the 36-Item short form instrument to the patients with T2DM (n = 45) admitted to the Tertiary hospital in Tebing Tinggi. Patients who had mental disorders, HIV-AIDS, liver disease, stage 4 chronic kidney disease, and pregnant women were excluded from the study. The patients’ quality of life was measured before and after interventions and analysed using the paired t-test. All analyses were performed using the Statistical Package for the Social Sciences (SPSS, version 22, Chicago, IL, USA) (p < 0.05 was considered significant). RESULTS: The mean age of the patients was 61.96 ± 6.45 (years). Most (66.7%) of them were females. The mean QOL (in the score) of the patients: before the intervention, 61.07 ± 15.13; after the intervention, 70.15 ± 14.23, there was a significant difference between groups with and without interventions, p < 0.001. CONCLUSION: Active contribution of pharmacists in the management of T2DM patients is urgent and important to improve the patients’ QOL.


2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Kosana Stanetić ◽  
Maja Račić ◽  
Vesna Kević

Introduction.The aim of the study was to find out the determinants of thequality of life in primary health care patients with type 2 diabetes.Methods. The cross-sectional study included 181 patients, aged 37 to 89 years,with diabetes mellitus type 2, registered with four family medicine practices.The assessment of health status was conducted using medical history, objectiveexamination, laboratory analyses, dilated eye exam, screening for distalsymmetric neuropathy and ankle-brachial index measurement. In evaluatingthe impact of diabetes mellitus on patients’ health status, a generic instrument,the self-administered WHOQOL-BREF questionnaire, was used. Multivariatelinear regression models were used to analyze the variables associated withthe quality of life.Results. Out of 181 adult patients with type 2 diabetes mellitus, 73 (40.3%)had diabetes for less than 5 years. The mean glycated hemoglobin (A1C) was7.55% and the mean serum levels of fasting glucose, total cholesterol, LDL-cholesterol,HDL-cholesterol and triglycerides were above the recommendedvalues. Most of the patients had comorbidities, chronic diabetes complicationsand used oral hypoglycemic agents in combination with insulin. Themultivariate regression analysis showed that the age, psychological health,nephropathy and environment were associated with the domain of physicalhealth. The determinants of psychological health were age, marital statusand environment. Older and single patients had lower scores, whereas thosewith a better living environment had higher scores in the domain of socialrelationship. The levels of glycemic control and gender have not been shownto be significant determinants of any of the four domains.Conclusion. The factors associated with the different domains of quality oflife in patients with type 2 diabetes are multiple, but mainly relate to age,living environment and diabetes complications. The results can be used as aguideline for defining measures that can improve the quality of life of patientswith type 2 diabetes


2020 ◽  
Vol 5 (1) ◽  
pp. 60
Author(s):  
Nur Amirah Shibraumalisi ◽  
Nafiza Mat Nasir ◽  
Mazapuspavina Md Yasin ◽  
Mohamad Rodi Isa

Introduction: Low health literacy (HL) is one of the contributing factors that leads to negative diabetic outcome. Quality of life (QOL) is a state of complete physical, mental and social wellbeing. There is limited evidence on association of HL and QOL among type 2 diabetes mellitus (T2DM), therefore the objectives of this study were to identify the HL and QOL status, to determine the association between HL and QOL and factors associated with QOL among T2DM patients. Methods: This was a cross sectional study involving patients with T2DM from two public primary care clinics. HL and QOL were measured using translated and validatedHLS – Asia Q16 and DQoL-BCI questionnaires respectively among T2DM patients. Results: The mean HL score was 12.39 (3.34), 17.7 % had “inadequate HL”, 25.7% had “problematic HL” and 56.6% had “sufficient HL”. The mean DQoL-BCI score was 32.09 (6.51). Lower QOL level was negatively associated with age (b -0.140; CI: -0.190, - 0.090; p<0.001), not obese (b -1.476; CI: -2.605, - 0.347; p<0.011), and HL level (b -0.425; CI: -0.59, - 0.259; p<0.001). Lower QOL level was positively associated with uncontrolled glycaemic status (HbA1c >6.5%)(b 1.308; CI: -0.042, 2.659; p<0.058), treatment with insulin (b 4.163; CI:1.538, 6.788; p<0.002) and combination treatment of insulin and oral hypoglycaemic agents (OHA) (b 2.450; CI:1.145, 3.756; p<0.001). Conclusions: This study demonstrated that age, body mass index, HL, glycaemic control, treatment with OHA and insulin were significantly associated with QOL. This suggest the importance of identifying high risk patients with poor QOL for targeted intervention.


2018 ◽  
Vol 1 (1) ◽  
pp. 1-10
Author(s):  
Azizah Nasution ◽  
Rany Simbolon ◽  
Hari Ronaldo Tanjung

Abstract. This study aimed to assess the characteristics, utilization of antihyperglycemic drugs, and to analyze the quality of life (QOL) in type 2 diabetes mellitus (T2DM) patients. This two-month prospective descriptive cross-sectional study was undertaken by distributing the European Quality of Life - 5 Dimensions 3 Level (EQ-5D-3L) questionnaire to the patients with T2DM  (n=50) admitted to Helvetia primary health center Medan to assessed their QOL. The patients’ characteristics and the utilization of antihyperglycemic drugs were assessed from the patients’ medical records using a self-designed questionnaire. The inclusion criteria were T2DM patients with age of 18 years or older,  had no mental disorders,  and agreed to sign the informed consent. The patients’ characteristics, their QOL, utilization of antihyperglycemic drugs, and association among their characteristics and QOL were analyzed using descriptive and Chi-Square tests. All analyses were performed using the Statistical Package for the Social Sciences (SPSS, version 19, Chicago, IL, USA) (p value <0.05 was considered significant). It was found that the mean age of the T2DM patients was 59.70 ± 10.44 (years). Most (66%) of them were females. Majority (80%) of the patients graduated from primary to senior high schools.  Nearly half (44%) of the patients was provided glibenclamide. The mean QOL of the patients was 0.79 ± 0.14. There was no significant association between the patients’ QOL and their characteristics (p values >0.05). This study proved that most of the T2DM patients were females. Glibenclamide was the most frequently prescribed drug for the patients. The QOL of the patients was 79% of full health. Keyword: Antihyperglycemic Drugs , EQ-5D, QOL, T2DM


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