Benign Gastrointestinal Mesenchymal BUMPS: A Brief Review of Some Spindle Cell Polyps With Published Names

2011 ◽  
Vol 135 (10) ◽  
pp. 1311-1319 ◽  
Author(s):  
Ahren C Rittershaus ◽  
Henry D Appelman

Context.—There are several benign, predominantly spindle cell, mesenchymal proliferations involving the mucosa and/or submucosa in the gut, which present as polyps and pathologists see as polypectomy specimens. These include perineuriomas, Schwann cell nodules, ganglioneuromas, leiomyomas of the muscularis mucosae, inflammatory fibroid polyps, and granular cell tumors. Objectives.—To evaluate these mesenchymal polyps for their morphologic, immunohistochemical, ultrastructural, and molecular characteristics and to determine some of their associations. Data Sources.—Personal observations based on years of analyzing endoscopic biopsies and a review of the world's literature. Conclusions.—These polyps do surface every so often. There is significant literature covering inflammatory fibroid polyps and granular cell tumors, but there is little literature about the other entities.

2020 ◽  
Vol 16 (2) ◽  
pp. 137-142
Author(s):  
Ali Alshahrani

Background: Smoking is an established predictor of type 2 diabetes. However, the link between smoking cessation and diabetes progression remains a subject of scholarly investigation. Objective: The objective of this systematic review is to establish the link between smoking cessation and diabetes. Data Sources: The study utilized conference abstracts and peer-reviewed journals that reported randomized controlled trials smoking cessation interventions for diabetes patients. Results: Results from the review were inconclusive on the link between smoking cessation and diabetes. On one hand, several researchers have confirmed a positive correlation between smoking cessation and decreased risk of diabetes. On the other hand, some researchers have demonstrated that immediate withdrawal of nicotine resulted in increased risk of diabetes; however, this risk reduces with time. Conclusion: The result of this review did not estblish a clear relationship between smoking cessation and diabates. Limitations: Compared to other studies examining the implication of smoking on chronic diseases, this study identified a very small number of trials evaluating the effect of smoking cessation on diabetes. The small number of studies implies that the results may not be suitable for generalization. Implication: Results from the review can help in the development of a tailored intervention for effective management of diabetes in smoking patients.


2021 ◽  
Vol 10 (2) ◽  
pp. 73
Author(s):  
Raquel Pérez-Arnal ◽  
David Conesa ◽  
Sergio Alvarez-Napagao ◽  
Toyotaro Suzumura ◽  
Martí Català ◽  
...  

The COVID-19 pandemic is changing the world in unprecedented and unpredictable ways. Human mobility, being the greatest facilitator for the spread of the virus, is at the epicenter of this change. In order to study mobility under COVID-19, to evaluate the efficiency of mobility restriction policies, and to facilitate a better response to future crisis, we need to understand all possible mobility data sources at our disposal. Our work studies private mobility sources, gathered from mobile-phones and released by large technological companies. These data are of special interest because, unlike most public sources, it is focused on individuals rather than on transportation means. Furthermore, the sample of society they cover is large and representative. On the other hand, these data are not directly accessible for anonymity reasons. Thus, properly interpreting its patterns demands caution. Aware of that, we explore the behavior and inter-relations of private sources of mobility data in the context of Spain. This country represents a good experimental setting due to both its large and fast pandemic peak and its implementation of a sustained, generalized lockdown. Our work illustrates how a direct and naive comparison between sources can be misleading, as certain days (e.g., Sundays) exhibit a directly adverse behavior. After understanding their particularities, we find them to be partially correlated and, what is more important, complementary under a proper interpretation. Finally, we confirm that mobile-data can be used to evaluate the efficiency of implemented policies, detect changes in mobility trends, and provide insights into what new normality means in Spain.


2005 ◽  
Vol 65 (1) ◽  
pp. 129-139 ◽  
Author(s):  
M. A. H Penna ◽  
M. A Villacorta-Corrêa ◽  
T. Walter ◽  
M. Petrere-JR

In order to decide which is the best growth model for the tambaqui Colossoma macropomum Cuvier, 1818, we utilized 249 and 256 length-at-age ring readings in otholiths and scales respectively, for the same sample of individuals. The Schnute model was utilized and it is concluded that the Von Bertalanffy model is the most adequate for these data, because it proved highly stable for the data set, and only slightly sensitive to the initial values of the estimated parameters. The phi' values estimated from five different data sources presented a CV = 4.78%. The numerical discrepancies between these values are of not much concern due to the high negative correlation between k and L<FONT FACE=Symbol>¥</FONT> viz, so that when one of them increases, the other decreases and the final result in phi' remains nearly unchanged.


2000 ◽  
Vol 3 (6) ◽  
pp. 591-596 ◽  
Author(s):  
Virpi V. Smith ◽  
Amanda J. Williams ◽  
Vas Novelli ◽  
Marian Malone

We report two infants with the acquired immunodeficiency syndrome (AIDS) and rectal bleeding due to cytomegalovirus (CMV) ileitis and colitis with minimal focal mucosal ulceration but with extensive leiomyolysis of the muscularis propria. Immunostaining and in situ hybridization for CMV showed numerous viral inclusions in the myocytes of the muscularis propria and vascular endothelium/smooth muscle with only occasional inclusions present in the muscularis mucosae. Colectomy was curative in one patient; in the other the bowel was only examined at postmortem.


2012 ◽  
Vol 6 (4) ◽  
pp. 467-470 ◽  
Author(s):  
Andreas-Christoforos Prigkos ◽  
Michail D. Nikolakis ◽  
Vasileios F. Kyriakopoulos ◽  
Konstantinos I. Tosios

2021 ◽  
Vol 13 (1) ◽  
pp. 129-148
Author(s):  
Muflihah Muflihah

Most of the generation (Arabic linguistic academics) have not comprehended the linguistic theories which initiated by Al-Jahid. This study aims to research on the concept of communication with the signs in Al-Jahid works. To identify these problems in depth and thoroughly, qualitative descriptive study was used. The primary data sources of this research were various sources, mainly Al Jahid book with documentation from the works of Al-Jahid and observation techniques based on the other books about Jahid ‘s point of view, such as Kamal Bisyri and other linguists. The results of this study concluded that: Al-Jahiz is an Arabic language expert who discussed the theory of non-verbal communication. In the case of learning a language, we also have to comprehend the theory of communication, especially communication with signs by Al-Jahiz. His thoughts were followed by several contemporary scholars. Thus, it is highly recommended to the Arabic researchesr to figure out the works of previous Arabic scholars which had been discussing about contemporary linguistic.


Cancer ◽  
1984 ◽  
Vol 53 (10) ◽  
pp. 2104-2110 ◽  
Author(s):  
In Sook Seo ◽  
Biagio Azzarelli ◽  
Thomas F. Warner ◽  
Michael P. Goheen ◽  
Gary E. Senteney
Keyword(s):  

2021 ◽  
Vol 15 (2) ◽  
pp. 43-54
Author(s):  
Brian Micallef

Up to a few years ago, the private rental market in Malta was a classic example of the dysfunction created by two diametrically opposed regimes – a rigidly-controlled one and a completely liberal one – co-existing side by side. Two recent reforms have sought to address this situation. The objective of this paper is to describe the state-of-play in the private rental market in Malta by providing a historical background to these recent developments. In addition to the distortions in the housing market that rent controls introduce, controls also contributed to the deterioration of the statistical infrastructure to collect data on this sector. From this perspective, the introduction of the 2020 rent reform for the post-1995 sector, in addition to providing a set of minimum standards to professionalize the market, also facilitated data collection efforts through the introduction of a rent register. This information provided an alternative source of information to complement the other data sources, which tend to be outdated, inadequate, or focus solely on specific segments of the market, thus allowing for a more detailed and complete view of the private rental market in Malta.


1989 ◽  
Vol 257 (1) ◽  
pp. G46-G51 ◽  
Author(s):  
P. K. Rangachari ◽  
D. McWade

Isolated mucosal preparations from the stomach are generally obtained by removing the external muscle layers, leaving intact the muscularis mucosae. By carefully dissecting off the muscularis mucosa, we have obtained "epithelial" preparations from the canine stomach. Such preparations responded to secretagogues, histamine, pentagastrin, and a cholinergic agonist (cis-2-methyl 4-dimethylaminomethyl 1,3-dioxolane methiodide). Epithelial preparations were, in general, more sensitive than mucosal preparations. Of the three secretagogues tested, histamine was the most consistent stimulant, with well-sustained responses being noted. Responses to the other agonists were more variable. Pentagastrin produced brief but explosive increases in acid output.


1993 ◽  
Vol 30 (2) ◽  
pp. 176-185 ◽  
Author(s):  
A. K. Patnaik

In a retrospective study, granular cell tumors in six dogs (Nos. 1–6), three cats (Nos. 1–3), one horse (No. 1), and one cockatiel ( Nymphicus hollandicus) (No. 1) and a meningioma with a granular cell component in one dog (No. 7) were examined histologically and immunohistochemically. These tumors were identified by histologic examination of surgical biopsy specimens, except in the horse, in which the tumor was an incidental finding at necropsy. These diagnoses were initially made by more than one pathologist. Five of the six granular cell tumors in the dogs were in the oral cavity; one of these was in the maxillary gingiva of a 6-month-old puppy. The tumors in the cats were located in the tongue, vulva, and digit. The tumor in the horse was in the lung, and the tumor in the cockatiel was in the periocular tissue. Histologically, all granular cell tumors were characterized by oval to polygonal cells of various sizes. The cells had abundant, pale, eosinophilic cytoplasm with distinct intracytoplasmic granules, distinct cell margins, and mostly central nuclei. In the dogs, the gingival tumor had a large amount of collagen tissue, the tumor in the tongue had dilated blood vessels, and the maxillary tumor in the puppy was more cellular than the other tumors. The tumors in the cats were more anaplastic than the other tumors; one, located in the digit, was considered malignant. The granules in all of the tumors stained with periodic acid-Schiff and were diastase resistant. On staining with Luxol fast blue, the granules of all tumors stained different shades of pink, with the exception of the tumor in the tongue of a cat, which stained bluish green. Immunocytochemically, all tumors except the tumor in the cockatiel reacted against antibodies to vimentin. The granular cell tumor in the lung of the horse and the intracranial meningioma in a dog reacted to the antibody S-100 protein; the tumor in the horse reacted to neuron-specific enolase; tumors in two dogs (gingiva and skin) reacted to L-antitrypsin, and the maxillary tumor also reacted to lysozyme; the malignant tumor in the digit of a cat and the periocular tumor in the cockatiel reacted to muscle common actin and actin; the tumor in the cockatiel also reacted to desmin. Results of these immunocytochemical studies suggest that granular cell tumors, like tumors composed of rhabdoid cells, clear cells, and oncocytes, can have similar morphologic features but be of different cellular origins.


Sign in / Sign up

Export Citation Format

Share Document