scholarly journals Acute Kidney Injury in a Child Receiving Vancomycin and Piperacillin/Tazobactam

2016 ◽  
Vol 21 (2) ◽  
pp. 169-175 ◽  
Author(s):  
Bethany W. Ibach ◽  
Emilie D. Henry ◽  
Peter N. Johnson
Keyword(s):  
Acute Kidney Injury ◽  
Care Facility ◽  
Kidney Injury ◽  
Pediatric Intensive Care ◽  
Multidrug Resistant ◽  
Probability Scale ◽  
Term Care ◽  
Long Term Care Facility ◽  
Increased Risk

Recent reports have described increased risk of acute kidney injury (AKI) in adults receiving concomitant vancomycin and piperacillin/tazobactam, but few reports exist in children. We describe an 8-year-old girl who was admitted to the pediatric intensive care unit with respiratory distress secondary to pneumonia. She began treatment with vancomycin and piperacillin/tazobactam. She developed AKI, and piperacillin/tazobactam and vancomycin were discontinued. Following a furosemide infusion, her AKI resolved and serum creatinine returned to baseline. She later resumed piperacillin/tazobactam monotherapy for multidrug-resistant tracheitis with no evidence of AKI and was eventually discharged to a long-term care facility. The Naranjo probability scale supports a probable drug-related adverse event. Clinicians must be aware of the possibility of AKI with this combination and should monitor renal function and vancomycin concentrations vigilantly. Future prospective studies are needed to explore the incidence and clinical characteristics associated with AKI after this combination in children.

Pneumonia in the Long-Term-Care Facility

2002 ◽  
Vol 23 (3) ◽  
pp. 159-164 ◽  
Author(s):  
Thomas J. Marrie
Keyword(s):  
Long Term Care ◽  
Care Facility ◽  
Multidrug Resistant ◽  
Term Care ◽  
Long Term Care Facility ◽  
Anticholinergic Medications ◽  
Care Facilities ◽  
Profound Disability ◽  
Common Infection

AbstractPneumonia is a common infection among residents of long-term-care facilities (LTCFs), with an incidence of 1.2 episodes per 1,000 patient-days. This rate is believed to be six- to tenfold higher than the rate of pneumonia among elderly individuals living in the community. The risk factors for pneumonia among residents of LTCFs are profound disability, bedridden state, urinary incontinence, difficulty swallowing, malnutrition, tube feedings, contractures, and use of benzodiazepines and anticholinergic medications. An elevated respiratory rate is often an early clue to pneumonia in this group of patients. Staphylococcus aureus (including methicillin-resistant S. aureus) and aerobic gram-negative bacilli (including multidrug-resistant isolates) are more frequent causes of pneumonia in this setting than in the community. Criteria have been developed that help identify patients for treatment in their LTCFs.

scholarly journals Multidrug-ResistantAcinetobacter baumanniiInfection, Colonization, and Transmission Related to a Long-Term Care Facility Providing Subacute Care

2014 ◽  
Vol 35 (4) ◽  
pp. 406-411 ◽  
Author(s):  
Eva Mortensen ◽  
Kavita K. Trivedi ◽  
Jon Rosenberg ◽  
Sara H. Cody ◽  
Janet Long ◽  
...  
Keyword(s):  
Long Term Care ◽  
Care Facility ◽  
Multidrug Resistant ◽  
Term Care ◽  
Term Care Facility ◽  
Long Term Care Facility ◽  
Subacute Care ◽  
Hospital Patients ◽  
Resistance Patterns

Objective.To investigateAcinetobacter baumanniiinfection, colonization, and transmission related to a long-term care facility (LTCF) providing subacute care (facility A).Methods.We reviewed facility A and affiliated local hospital records for facility A residents withA. baumanniiisolated during the period January 2009 through February 2010 and comparedA. baumanniiantimicrobial resistance patterns of residents with those of hospital patients. During March 2010, we implemented a colonization survey of facility A residents who received respiratory support or who could provide sputum samples and looked forA. baumanniicolonization risks. Available clinical and survey isolates underwent pulsed-field gel electrophoresis (PFGE); PFGE strains were linked with overlapping stays to identify possible transmission.Results.During the period January 2009 through February 2010, 33 facility A residents hadA. baumanniiisolates; all strains were multidrug resistant (MDR), which was a significantly higher prevalence of MDR strains than that found among isolates from hospital patients (81 [66%] of 122 hospital patient isolates were MDR;P< .001). The sputum survey found that 14 (20%) of 70 residents hadA. baumanniicolonization, which was associated with ventilator use (adjusted odds ratio, 4.24 [95% confidence interval, 1.06–16.93]); 12 (86%) of 14 isolates were MDR. Four facility A resident groups clustered with 3 PFGE strains and overlapping stays. One of these facility A residents also clustered with 3 patients at an affiliated hospital.Conclusions.We documented substantial MDRA. baumanniiinfections and colonization with probable intra- and interfacility spread associated with a single LTCF providing subacute care. Given the limited infection prevention and antimicrobial stewardship resources in such settings, regional collaborations among facilities across the spectrum of health care are needed to address this MDR threat.

Emergence of multidrug-resistant Proteus mirabilis in a long-term care facility in Croatia

2016 ◽  
Vol 128 (11-12) ◽  
pp. 404-413 ◽  
Author(s):  
Branka Bedenić ◽  
Nataša Firis ◽  
Vesna Elveđi-Gašparović ◽  
Marija Krilanović ◽  
Krešimir Matanović ◽  
...  
Keyword(s):  
Proteus Mirabilis ◽  
Long Term Care ◽  
Care Facility ◽  
Multidrug Resistant ◽  
Term Care ◽  
Term Care Facility ◽  
Long Term Care Facility

Multidrug-Resistant Gram-Negative Bacteria in a Long-Term Care Facility: Prevalence and Risk Factors

2008 ◽  
Vol 56 (7) ◽  
pp. 1276-1280 ◽  
Author(s):  
Aurora Pop-Vicas ◽  
Susan L. Mitchell ◽  
Ruth Kandel ◽  
Robert Schreiber ◽  
Erika M. C. D'Agata
Keyword(s):  
Risk Factors ◽  
Long Term Care ◽  
Care Facility ◽  
Multidrug Resistant ◽  
Gram Negative Bacteria ◽  
Term Care ◽  
Gram Negative ◽  
Term Care Facility ◽  
Long Term Care Facility
Sign in / Sign up

Export Citation Format

Share Document