Preclinical Evaluation of Antihypertensive Activity of Combination of Herbs Extract in Wistar Rats

2020 ◽  
Vol 13 (5) ◽  
pp. 2069
Author(s):  
Bhavika D. Satone ◽  
Atul A. Deshmukh ◽  
Vaishali R. Undale
Keyword(s):  
Wistar Rats ◽  
Antihypertensive Activity ◽  
Preclinical Evaluation

scholarly journals Preclinical evaluation of nephroprotective potential of a probiotic formulation LOBUN on Cyclosporine-A induced renal dysfunction in Wistar rats

2017 ◽  
Vol 53 (2) ◽  
Author(s):  
Kambham Venkateswarlu ◽  
Thakur Heerasingh ◽  
Chilamakuru Naresh Babu ◽  
Singirisetty Triveni ◽  
Suroju Manasa ◽  
...  
Keyword(s):  
Renal Dysfunction ◽  
Cyclosporine A ◽  
Wistar Rats ◽  
Preclinical Evaluation

Antihypertensive activity of diethyl-4,4ʹ-dihydroxy-8,3ʹ-neolign-7,7ʹ-dien-9,9ʹ-dionate: A continuation study in L-NAME treated wistar rats

2019 ◽  
Vol 858 ◽  
pp. 172482
Author(s):  
Arjun Singh ◽  
B. Sathish Kumar ◽  
Hina Iqbal ◽  
Sarfaraz Alam ◽  
Pankaj Yadav ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Antihypertensive Activity

scholarly journals Preclinical evaluation of anxiolytic activity of Enhydra Flactuans leaves on albino Wistar rats

2019 ◽  
Vol 5 (6) ◽  
pp. 1167-1171
Author(s):  
Kousik Saha ◽  
Mriganka Sekhar Bala ◽  
Trisha Sen ◽  
Mrityunjoy Majumdar
Keyword(s):  
Wistar Rats ◽  
Anxiolytic Activity ◽  
Preclinical Evaluation

Ultrastructural Investigation of Spontaneous Pituitary Adenomas in Aging Sprague-Dawley Rats

1982 ◽  
Vol 40 ◽  
pp. 216-217
Author(s):  
D. J. McComb ◽  
J. Beri ◽  
F. Zak ◽  
K. Kovacs
Keyword(s):  
Microscopic Study ◽  
Pituitary Adenomas ◽  
Wistar Rats ◽  
Microscopic Level ◽  
Sprague Dawley ◽  
Prolactin Cells ◽  
Light Microscopic Level ◽  
Ultrastructural Investigation ◽  
Sprague Dawley Rats ◽  
Long Evans

Investigation of the spontaneous pituitary adenomas in rat have been limited mainly to light microscopic study. Furth et al. (1973) described them as chromophobic, secreting prolactin. Kovacs et al. (1977) in an ul trastructural investigation of adenomas of old female Long-Evans rats, found that they were composed of prolactin cells. Berkvens et al. (1980) using immunocytochemistry at the light microscopic level, demonstrated that some spontaneous tumors of old Wistar rats could contain GH, TSH or ACTH as well as PRL.

Light and electron microscopic investigation of adenohypophyses of germfree, food-restricted, and germfree-food restricted aging, male lobund-wistar rats

1988 ◽  
Vol 46 ◽  
pp. 352-353
Author(s):  
G. Ilse ◽  
K. Kovacs ◽  
N. Ryan ◽  
T. Sano ◽  
L. Stefaneanu ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Microscopic Investigation ◽  
Electron Microscopic Investigation ◽  
Aging Male ◽  
Sprague Dawley ◽  
Electron Microscopic ◽  
Sprague Dawley Rats ◽  
Old Rats ◽  
Ad Libitum ◽  
Microscopic Findings

Germfree state and food restriction have been shown to increase life span and delay tumor occurrence in rats. We report here the histologic, immunocytochemical and electron microscopic findings of adenohypophyses of aging, male Lobund-Wistar rats raised at Lobund Laboratories. In our previous study, the morphologic changes in the adenohypophyses of old rats have been extensively investigated by histology, immunocytochemistry and electron microscopy. Lactotroph adenomas were frequent in Long-Evans and Sprague-Dawley rats, whereas gonadotroph adenomas were frequent in Sprague-Dawley and Wistar rats.Male Lobund-Wistar rats were divided into four groups: 1) conventional, which were raised under normal non-germfree environment and received food ad libitum; 2) germfree-food ad libitum; 3) conventional environment-food restricted and 4) germfree-food restricted. The adenohypophyses were removed from 6-month-, 18-month- and 30-month-old rats. For light microscopy, adenohypophyses were fixed in formalin and embedded in paraffin.

Surface epithelial ultrastructure of the polycystic ovary in the BB wistar rat

1986 ◽  
Vol 44 ◽  
pp. 252-253
Author(s):  
R. C. Kaufmann ◽  
F. K. Khosho ◽  
K. S. Amankwah
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Wistar Rats ◽  
Polycystic Ovary ◽  
Wistar Rat ◽  
Polycystic Ovaries ◽  
Chemical Diabetes ◽  
Scanning Electron

Diabetes decreases the fertility of females, but the mechanisms are not completely understood. In our investigations, we have found that 13% of the female BB Wistar rats that spontaneously developed chemical diabetes had persistent estrous. In this study the ovaries of these rats were examined by scanning electron microscopy(SEM) and compared to normal-cycling controls as well as to rats that had developed polycystic ovaries(PCO) by exposure to constant 1ight.

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