Lived Experiences of Egyptian Women with Breast Cancer Receiving Chemotherapy

2019 ◽  
Vol 10 (6) ◽  
pp. 678
Author(s):  
Sanaa Loutfy Abdel-Ghany ◽  
Bassamat Omar Ahmed ◽  
Safaa Mohammed Hassanein ◽  
Abeer Saad Zaghloul Eswi
Keyword(s):  
Breast Cancer ◽  
Lived Experiences ◽  
Egyptian Women

NRF2 AND P73 POLYMORPHISMS IN EGYPTIAN WOMEN WITH BREAST CANCER

2015 ◽  
Vol 33 (1-2) ◽  
pp. 82-95
Author(s):  
Iman Hassan ◽  
Hanan Atia ◽  
Heba Abd El-Aziz ◽  
Mahmoud Kamel
Keyword(s):  
Breast Cancer ◽  
Egyptian Women

180P Factors associated with late-stage diagnosis of breast cancer among Egyptian women

2021 ◽  
Vol 32 ◽  
pp. S96
Author(s):  
H.M. Ismail ◽  
S. Mokhtar ◽  
H. El-Mansy
Keyword(s):  
Breast Cancer ◽  
Late Stage ◽  
Factors Associated ◽  
Late Stage Diagnosis ◽  
Egyptian Women

scholarly journals Role of CD4+ CD25+ FOXP3+ regulatory T-cells and human papilloma virus infection in Egyptian Women with breast cancer

2019 ◽  
Author(s):  
Amany Tawfeik ◽  
Ahmed Mora ◽  
Ahmed Osman ◽  
Nabila Elsheikh ◽  
Mohamed Elrefaei
Keyword(s):  
Breast Cancer ◽  
T Cells ◽  
High Risk ◽  
Human Papilloma Virus ◽  
Cd8 T Cells ◽  
Peripheral Blood ◽  
Early Stage ◽  
Significant Proportion ◽  
Papilloma Virus ◽  
Egyptian Women

Abstract Several subsets of regulatory CD4+ T cells (CD4+ Tregs) have been described in peripheral blood and tumor microenvironment and blood of breast cancer (BC) patients and may play a key role in the progression of BC. High-risk human papilloma virus (HPV) have a causal role in a significant proportion of cervical, and head, and neck tumors and may play an important role in evoking neoplasia in BC. In this study we assessed the prevalence of CD4+Tregs (CD4+CD25+ FOXP3+ cells) and CD8+T cells by flow cytometry in peripheral blood from a total of 55 Egyptian women, including 20 treatment-naïve BC, 15 with breast benign lesions (BBL) and 20 healthy volunteers (HV). High-risk HPV genotype type 16, 18, and 31 was investigated in breast tissue from all BC and BBL patients using Real-Time PCR. HPV was detected in 4 BC, but in none of BBL patients. The frequency of CD4+ Tregs was significantly higher in BC compared to BBL and HV, (p < 0.001). In addition, we observed a significantly higher frequency of CD8+ T cells in peripheral blood of patients with late stage III compared to early stage I and II BC (p = 0.011). However, there was no significant association between the ratio of CD8+ T cell to CD4+ Tregs frequencies and the expression of Estrogen Receptor (ER), Progesterone Receptor (PR), and Human Epidermal Growth Factor Receptor 2 (HER2). In conclusion, CD4+ Tregs may contribute to progression BC in Egyptian women with HPV infection. The potential role CD4+ Tregs as a prognostic or predictive parameter should be analyzed in a larger longitudinal study with sufficient follow-up time.

scholarly journals Effect of different modalities of treatment on the quality of life of breast cancer patients in Egypt

1997 ◽  
Vol 3 (1) ◽  
pp. 68-81
Author(s):  
Fatma M. El Sharkawi ◽  
Mahmoud F. Sakr ◽  
Hoda Y. Atta ◽  
Hafez M. Ghanem
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Therapy ◽  
Adjuvant Therapy ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Breast Cancer Therapy ◽  
Egyptian Women ◽  
The Impact

The impact of breast cancer therapy on the quality of life [QL] of Egyptian women was studied. Patients were divided into four groups:1:mastectomy alone;2:surgery plus radiotherapy;3:surgery plus chemotherapy;and 4:triple modality. The results revealed that all the four domains of QL of women having adjuvant therapy [groups 2, 3, or 4] were significantly altered compared to those who underwent mastectomy alone. Triple modality adversely affected global QL the most compared to radiotherapy or chemotherapy;radiotherapy had significantly less effect on QL compared to chemotherapy. Triple modality predicted the worst QL. QL measures should be incorporated with the traditional end points for evaluation of treatment and patients given health education on the effects of each therapy

scholarly journals (Association of Methylenetetrahydrofolate Reductase (MTHFR) A1298C gene polymorphism with Breast Cancer in Egyptian women)

2016 ◽  
Vol 11 (1) ◽  
pp. 70-79
Author(s):  
Besheer El-Sayed Bayomy ◽  
Afaf Mohammed El-said ◽  
Noha Mohamed Said ◽  
Mona Mohammed Ibrahim
Keyword(s):  
Breast Cancer ◽  
Gene Polymorphism ◽  
Methylenetetrahydrofolate Reductase ◽  
Mthfr A1298c ◽  
Egyptian Women

Metal-Induced Oxidative Stress in Egyptian Women with Breast Cancer

2012 ◽  
Vol 02 (07) ◽  
Author(s):  
Rania Hamed Abdel Rahman
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Egyptian Women

Frequency of BRCA1 (185delAG and 5382insC) and BRCA2 (6174delT) mutations in Egyptian women with breast cancer compared to healthy controls

Meta Gene ◽  
2018 ◽  
Vol 15 ◽  
pp. 35-41 ◽  
Author(s):  
Amoura Abou-El-Naga ◽  
Ahmed Shaban ◽  
Hayam Ghazy ◽  
Afaf Elsaid ◽  
Rami Elshazli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Healthy Controls ◽  
Egyptian Women
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