Effects of Examination Stress on Blood Cell Count in First Year Medical Students

2014 ◽  
Vol 2 (2) ◽  
pp. 17
Author(s):  
Jayanti Singh ◽  
Nivriti Singh ◽  
Hemant Kumar Singh ◽  
Yogesh Tripathi ◽  
J L Agarwal
2020 ◽  
Vol 8 (4) ◽  
pp. 288-294
Author(s):  
Dr. Inderjit Singh ◽  
◽  
Dr. Yogesh Singh ◽  
Dr. Bibhava Vikramaditya ◽  
Santosh Singh ◽  
...  

Author(s):  
G.V. Chernova ◽  
E.V. Dykova ◽  
V.V. Sidorov ◽  
M.A. Timofeeva ◽  
L.V. Shiryaeva

There were conducted biometric studies and quantitative assessment of variability of indexes of white blood cell count of healthy children of the first year of life (data of the biometric analysis are presented in graphic form). It was revealed that the total number of white blood cells in 78,7 % cases was determined genetically, defining differences in variability of indexes at boys and girls. At the same time cells of a granulocytes row expressed such feature only in 12,2 % of cases. Change in the content of granulocyte row cells in the peripheral blood of children of the first year of life in the conditions of the non-ionizing radiation of natural origin demonstrates the formation of a response of adaptation system components. The data on dynamics of the relations of granulocytes and lymphocytes (indexes) obtained by authors have a theoretical and applied significance for development of criteria for evaluation the functional condition of adaptation system and health of children.


1992 ◽  
Vol 68 (05) ◽  
pp. 583-588 ◽  
Author(s):  
Annika Dotevall ◽  
Christina Rångemark ◽  
Elsa Eriksson ◽  
Jack Kutti ◽  
Hans Wadenvik ◽  
...  

SummarySmoking is a risk factor for the development of atherosclerotic cardiovascular disease, in men as well as in women. An increased urinary excretion of the thromboxane metabolite 2,3-dinor-thromboxane B2 (Tx-M) has been observed in smokers of both genders, suggesting that cigarette smoking may facilitate cardiovascular disease via an action on the platelets. The present study addressed the hypothesis that the increased Tx-M excretion in female smokers reflects a true facilitation of platelet reactivity in vivo, rather than an increased destruction of the platelets. In healthy female volunteers (aged 20–46 years, 18 smokers and 17 non-smokers) platelet life-span and indices of platelet activity were determined, together with plasma levels of plasminogen activator inhibitor-1 (PAI-1), fibrinogen, peripheral blood cell counts and hematocrit. The urinary excretion of Tx-M was higher in smokers than in non-smokers (361 vs. 204 pg/mg creatinine, respectively, p <0.05), while plasma and urinary β-thromboglobulin, plasma platelet factor 4, platelet mean life-span and platelet production rate did not differ between the groups. PAI-1 activity, white blood cell count and hematocrit were higher in smokers than in non-smokers (p <0.05). These data indicate that smoking facilitates platelet formation of thromboxane A2 without affecting platelet survival; i.e. it increases the activity of platelets without affecting their viability to a measurable extent. Such an increase in platelet activity, operating in parallel to a reduced fibrinolytic activity and a higher hematocrit and white blood cell count, may play an etiological role in smoking-induced cardiovascular disease in women.


2018 ◽  
Vol 12 (2) ◽  
pp. 46-52 ◽  
Author(s):  
A.I. Varlamova

The purpose of the research: study of the influence of increased doses of fenbendazole supramolecular complex (FSMC) on sheep’s organism. Materials and methods. The experiment was carried out at the Podolsk Department of All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants named after K. I. Skryabin on 20 manorial invasion-free sheep aged 2-3 years old. Animals were divided according to the principle of analogues into 4 groups, 5 heads in each group. Animals of the 1, 2 and 3 group were orally administered with FSMC given as a single dose of 2, 6, 10 mg/kg, respectively, according to the active substance, i.e in therapeutic and in a dose increased by 3 and 5 times. Sheep of the fourth group didn’t receive the drug and they were as control. Study of clinical, hematological and biochemical parameters of animals from all groups was conducted 1 day before and in 1, 3, 5 days after administration of the drug by means of standard methods. Results and discussion. FSMC in therapeutic dose as well as in a dose increased by 3 and 5 times doesn’t have negative influence on clinical, hematological and biochemical parameters of the sheep. State of the sheep, which received the drug in doses of 20, 60, 100 mg/kg, was within the physiologically normal state and didn’t differ from the state before administration of the drug and from the animals of the control group. Drug security index exceeds 5. Red blood cell count, white blood cell count, hemoglobin count, leukogram parameters as well as biochemical parameters of blood: activity of alkaline phosphatase and amylase, bilirubin, creatinine, urea and glucose counts were within normal limits and didn’t differ from the parameters of the control animals.


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