scholarly journals Letter to the Editor: Radiation for Prior DCIS is a Risk Factor for Death From Invasive Breast Cancer

2020 ◽  
Vol 18 (5) ◽  
pp. xliiia ◽  
Author(s):  
Victoria Sopik ◽  
Vasily Giannakeas ◽  
Steven Narod
2011 ◽  
Vol 80 (2) ◽  
pp. 90 ◽  
Author(s):  
Sun Hyoung Shin ◽  
Byung Chun Kim ◽  
Young Ju Song ◽  
Hyun Chul Yoon ◽  
Jin Seong Cho ◽  
...  

2017 ◽  
Vol 06 (03) ◽  
pp. 106-109 ◽  
Author(s):  
Purnima Thakur ◽  
Rajeev Kumar Seam ◽  
Manoj K. Gupta ◽  
Manish Gupta ◽  
Mukesh Sharma ◽  
...  

Abstract Context: Breast cancer incidence is increasing rapidly in India. The lifestyle, built, genetic makeup, reproductive and breastfeeding patterns are quite different in Indian females when compared to the Western population. Generalizing the Western data to the population residing in the Himalayan region would breed inaccuracies. Aim: The aim of our study was to identify risk factors in our own population in a Western Himalayan state of Himachal Pradesh, India. Subjects and Methods: A case–control study with 377 cases of invasive breast cancer and 346 hospital-based controls was conducted for 1 year. The data were collected by interviewing the individuals during their visit to hospital using a questionnaire. The data were analyzed using standard statistical techniques using SPSS version 17 software. Results: Factors found to have strong association with invasive breast cancer on multivariate analysis are late age at first childbirth >30 years, which is the strongest risk factor associated, late age of menopause > 50 years, high socioeconomic class, and age of female above 50 years. Conclusion: In our females, age >50 years, late age of menopause (>50 years), late age at first childbirth (>30 years), and high socioeconomic status were found to be major risk factors associated with breast cancer. Several factors implicated in the Western data were not found to be significant in our study. We need to identify such aspects in reproductive and breastfeeding patterns of women and spread awareness regarding the same.


2015 ◽  
Vol 61 (5) ◽  
pp. 411-416 ◽  
Author(s):  
Damila Cristina Trufelli ◽  
Leandro Luongo de Matos ◽  
Patricia Xavier Santi ◽  
Auro Del Giglio

Summary Background: to evaluate if time between surgery and the first adjuvant treatment (chemotherapy, radiotherapy or hormone therapy) in patients with breast cancer is a risk factor for lower overall survival (OS). Method: data from a five-year retrospective cohort study of all women diagnosed with invasive breast cancer at an academic oncology service were collected and analyzed. Results: three hundred forty-eight consecutive women were included. Time between surgery and the first adjuvant treatment was a risk factor for shorter overall survival (HR=1.3, 95CI 1.06-1.71, p=0.015), along with negative estrogen receptor, the presence of lymphovascular invasion and greater tumor size. A delay longer than 4 months between surgery and the first adjuvant treatment was also associated with shorter overall survival (cumulative survival of 80.9% for delays ≤ 4 months vs. 72.6% for delays > 4 months; p=0.041, log rank test). Conclusion: each month of delay between surgery and the first adjuvant treatment in women with invasive breast cancer increases the risk of death in 1.3-fold, and this effect is independent of all other well-established risk factors. Based on these results, we recommend further public strategies to decrease this interval.


2021 ◽  
pp. 30-33
Author(s):  
David Jaynes ◽  
Paul Switzer

The purpose of this article is to provide background information and the current understanding of a less familiar cause of female breast cancer; exposure to ultraviolet light at night. Breast cancer is a common disease that causes significant morbidity and mortality in women. There are several risk factors for breast cancer, most of which are genetic and environmental in nature. An often-overlooked risk factor is exposure to blue light during night shift work, which decreases melatonin production. One of the many cancer-preventing properties of melatonin is to limit estrogen production. Increased lifetime exposure to estrogen is a well-known cause of breast cancer. Awareness of nighttime blue light exposure as a breast cancer risk factor by women doing night shift work and those exposed to nighttime light via smartphones and laptops, is essential information to know so that protective measures can be taken.


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