scholarly journals Global functioning among middle-aged patients with chronic schizophrenia: the role of medication, working memory and verbal comprehension

2019 ◽  
Vol 35 (2) ◽  
pp. 204-213 ◽  
Author(s):  
Maria Ruiz-Iriondo ◽  
Karmele Salaberria ◽  
Enrique Echeburua ◽  
Alvaro Iruin ◽  
Olga Gabaldón Poc ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Social Functioning ◽  
Cognitive Performance ◽  
Verbal Learning ◽  
Chronic Phase ◽  
Chronic Schizophrenia ◽  
Middle Aged ◽  
Global Functioning ◽  
Aged Patients

The chronic phase of schizophrenia is characterized by illness progression and patients encountering difficulties to return to premorbid level of functioning. The objective of this study was to describe the characteristics of a sample of patients with chronic schizophrenia, as well to assess differences between patients under and over 45 years of age. In a clinical sample of 77 chronic schizophrenia patients, we assessed basic symptoms, cognitive performance, social functioning and quality of life. All participants obtained very high scores in residual symptoms, and no differences in sociodemographic or clinical characteristics between the age groups were found. Younger patients had better cognitive performance and older patients obtained better scores for social functioning and quality of life. Number of psychotropic drugs, verbal learning delayed of SCIP, errors in WCST, Similarities and Digit Symbol Coding of WAIS were the most important variables to predict global functioning of patients over 45 years old. Increasing our understanding of differences in characteristics of the chronic phase of the illness and the profile of functioning at different ages, may help us design intervention strategies to improve adaptation in young and middle-aged patients with chronic schizophrenia.

Perspectives, Preferences, Care Practices, and Outcomes Among Older and Middle-Aged Patients With Late-Stage Cancer

2004 ◽  
Vol 22 (24) ◽  
pp. 4907-4917 ◽  
Author(s):  
Julia Hannum Rose ◽  
Elizabeth E. O'Toole ◽  
Neal V. Dawson ◽  
Renee Lawrence ◽  
Diana Gurley ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Patients ◽  
Perceived Quality ◽  
Therapeutic Interventions ◽  
Middle Aged ◽  
Aged Patients ◽  
Perceived Quality Of Life ◽  
Care Practices ◽  
Aggressive Care

PurposeTo evaluate relationships among physician and cancer patient survival estimates, patients' perceived quality of life, care preferences, and outcomes, and how they vary across middle-aged and older patient groups.Patients and MethodsSubjects were from the Study to Understand Prognoses and Preferences for Risks of Treatments (SUPPORT) prospective cohort studied in five US teaching hospitals (from 1989 to 1994), and included 720 middle-aged (45 to 64 years) and 696 older (≥ 65 years) patients receiving care for advanced cancer. Perspectives were assessed in physician and patient/surrogate interviews; care practices and outcomes were determined from hospital records and the National Death Index. General linear models were used within age groups to obtain adjusted estimates.ResultsAlthough most patients had treatment goals to relieve pain, treatment preferences and care practices were linked only in the older group. For older patients, preference for life-extending treatment was associated with more therapeutic interventions and more documented discussions; cardiopulmonary resuscitation (CPR) preference was linked to more therapeutic interventions and longer survival. For middle-aged patients, better perceived quality of life was associated with preferring CPR. In both groups, patients' higher survival estimates were associated with preferences for life-prolonging treatment and CPR; physicians' higher survival estimates were associated with patients' preferences for CPR, fewer documented treatment limitation discussions about care, and actual 6-month survival. More discussions were associated with readmissions and earlier death. More aggressive care was not related to outcomes.ConclusionFewer older patients preferred CPR or life-prolonging treatments. Although older patients’ goals for aggressive treatment were related to care, this was not so for middle-aged patients. Aggressive care was not related to prolonged life in either group.

Assessment of Quality of Life in Chronic Renal Disease Patients Undergoing Hemodialysis at Public Hospital, Lahore

2019 ◽  
Vol 1 (2) ◽  
Author(s):  
Mahrukh Ali ◽  
Maryam Naveed ◽  
Mehmoona Khan ◽  
Muhammad Arif Khan
Keyword(s):  
Quality Of Life ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Sampling Technique ◽  
Sociodemographic Factors ◽  
Cross Sectional Study ◽  
Middle Aged ◽  
Aged Patients ◽  
Cross Sectional

Quality of life of chronic renal disease patients is affected by several factors, depending on stage of disease, type of treatment and sociodemographic factors Objective: To assess the quality of life undergoing hemodialysis patients Methods: A cross-sectional study was carried out at Sir Ganga Ram Hospital, Lahore during February to May-2019. Patients suffering from chronic renal disease were included in the study and uncooperative patients were excluded in the study. Total 100 samples of chronic renal disease patients were selected through non-probability convenient sampling technique. Patients were assessed through pre-tested questionnaire. SPSS version 21.0 was used for data analysis Results: According to results 39% patients reported that they were suffering from depression, 47% patients of chronic renal disease were unemployed, 28% patients were malnourished and 98% patients were having 3 or more dialysis sessions per week. Also only 26% patients thought that quality of life of older patients is better while 74% considered it poor. Only 77% patients thought that quality of life of middle aged patients is better while 23% patients considered that quality of life of middle aged patients was poor. 42% patients thought that quality of life of young aged patients is better while 58%considered it poor. Conclusions: Malnutrition, unemployment and hypertension are the factors affecting the quality of life in patients undergoing hemodialysis in this study. The quality of life of middle aged patients was comparatively better. 

scholarly journals Endogenous Subclinical Hyperthyroidism Affects Quality of Life and Cardiac Morphology and Function in Young and Middle-Aged Patients*

2000 ◽  
Vol 85 (12) ◽  
pp. 4701-4705 ◽  
Author(s):  
Bernadette Biondi ◽  
Emiliano Antonio Palmieri ◽  
Serafino Fazio ◽  
Carmela Cosco ◽  
Maria Nocera ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Subclinical Hyperthyroidism ◽  
Middle Aged ◽  
Aged Patients ◽  
Cardiac Morphology ◽  
And Function

scholarly journals Quality of life and health status in middle-aged presumed healthy Slovenian family practice attendees

2021 ◽  
Vol 60 (3) ◽  
pp. 182-189
Author(s):  
Matic Tement ◽  
Polona Selič-Zupančič
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Positive Association ◽  
Female Gender ◽  
Middle Aged ◽  
Aged Patients ◽  
Physically Active ◽  
Clinical Variables ◽  
Related Quality

Abstract Background There is a gap in our knowledge of health-related quality of life (HRQoL) in a population presumed healthy, so this study aimed to assess the associations between HRQoL, demographics and clinical variables. Methods The participants were attendees, presumed healthy, at 40 pre-selected model family medicine practices (MFMPs), aged between 30 and 65 years and recruited during a preventive check-up in 2019. Each MFMP pragmatically invited 30 attendees to voluntarily participate. The EQ-5D questionnaire was administered as a measure of HRQoL; the independent variables were demographic characteristics, smoking, alcohol consumption, stress perception, physical activity, signs of depression, cardiovascular risk, body mass index, blood pressure values, and blood sugar and lipidogram laboratory test values. Ordinal logistic regression was used to calculate associations between self-assessed quality of life, demographics, and clinical variables, with P<0.05 set as statistically significant. Results Of 986 participants, 640 (64.9%) were women and 346 (35.1%) men, aged 42.7±8.6 years. The average values for the EQ-5D-3L were 0.91±0.15. In the multivariate model, a positive association between adequate physical activity (p=0.003), and a negative association between higher age (p<0.001), female gender (p=0.009), signs of depression (p<0.001), stress (p=0.013), and EQ-5D score were identified. Conclusion Given that physical activity was shown to be positively associated with HRQoL, it is of the utmost importance for family physicians to motivate their middle-aged patients, especially women and those with signs of depression and excessive stress, to adopt a more rigorously physically active lifestyle.

The post-aSAH syndrome: a self-reported cluster of symptoms in patients with aneurysmal subarachnoid hemorrhage

2020 ◽  
Vol 132 (5) ◽  
pp. 1556-1565 ◽  
Author(s):  
Tonje Haug Nordenmark ◽  
Tanja Karic ◽  
Cecilie Røe ◽  
Wilhelm Sorteberg ◽  
Angelika Sorteberg
Keyword(s):  
Quality Of Life ◽  
Subarachnoid Hemorrhage ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Verbal Learning ◽  
Emotional Problems ◽  
Chronic Phase ◽  
Residual Symptoms ◽  
Quality Of Life Questionnaires ◽  
Recovery Group

OBJECTIVEAlthough many patients recover to a good functional outcome after aneurysmal subarachnoid hemorrhage (aSAH), residual symptoms are very common and may have a large impact on the patient’s daily life. The particular cluster of residual symptoms after aSAH has not previously been described in detail and there is no validated questionnaire that covers the typical problems reported after aSAH. Many of the symptoms are similar to post-concussion syndrome, which often is evaluated with the Rivermead Post-Concussion Symptoms Questionnaire (RPQ). In the present study, the authors therefore performed an exploratory use of the RPQ as a template to describe post-aSAH syndrome.METHODSThe RPQ was administered to 128 patients in the chronic phase after aSAH along with a battery of quality-of-life questionnaires. The patients also underwent a medical examination besides cognitive and physical testing. Based on their RPQ scores, patients were dichotomized into a “syndrome” group or “recovery” group.RESULTSA post-aSAH syndrome was seen in 33% of the patients and their symptom burden on all RPQ subscales was significantly higher than that of patients who had recovered on all RPQ subscales. The symptom cluster consisted mainly of fatigue, cognitive problems, and emotional problems. Physical problems were less frequently reported. Patients with post-aSAH syndrome scored significantly worse on mobility and pain scores, as well as on quality-of-life questionnaires. They also had significantly poorer scores on neuropsychological tests of verbal learning, verbal short- and long-term memory, psychomotor speed, and executive functions. Whereas 36% of the patients in the recovery group were able to return to their premorbid occupational status, this was true for only 1 patient in the syndrome group.CONCLUSIONSApproximately one-third of aSAH patients develop a post-aSAH syndrome. These patients struggle with fatigue and cognitive and emotional problems. Patients with post-aSAH syndrome report more pain and reduced quality of life compared to patients without this cluster of residual symptoms and have larger cognitive deficits. In this sample, patients with post-aSAH syndrome were almost invariably excluded from return to work. The RPQ is a simple questionnaire covering the specter of residual symptoms after aSAH. Being able to acknowledge these patients’ complaints as a defined syndrome using the RPQ should help patients to accept and cope, thereby alleviating possible secondary distress produced.

Effect of Home-Based Intervention on Hospital Readmission and Quality of Life in Middle-Aged Patients with Severe Congestive Heart Failure: A 12-Month Follow Up Study

2003 ◽  
Vol 2 (2) ◽  
pp. 105-111 ◽  
Author(s):  
I. Vavouranakis ◽  
E. Lambrogiannakis ◽  
G. Markakis ◽  
A. Dermitzakis ◽  
Z. Haroniti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Congestive Heart Failure ◽  
Hospital Readmission ◽  
Severe Congestive Heart Failure ◽  
Middle Aged ◽  
Aged Patients ◽  
Home Based ◽  
Home Based Intervention

Objective: Home care surveillance has been shown to reduce hospital readmission and improve functional status and quality of life of elderly patients with mild to moderate or severe congestive heart failure and in younger patients candidates for transplantation. The present study aimed to investigate the effect of home-based intervention on hospital readmission and quality of life of middle-aged patients with severe congestive heart failure. Methods: Thirty-three patients aged 50–75 (mean age 65.4±6.7) with class III and IV congestive heart failure were included in this observational, community-based study. Intervention consisted of intensive home surveillance of patients, including frequent home visits associated with laboratory tests and telephone contacts to implement standard therapy, treat early symptoms and provide psychological support. Results: Admissions for cardiovascular reasons decreased from 2.143±1.11 for the year before the initiation of the study to 1.25±1 after its completion ( P=0.0005). Quality of life improved, as showed by a decrease of the mean score of the Minnesota Living with Heart Failure Questionnaire from 2.68±0.034 to 2.33±0.032 ( P=0.0001). Conclusion: Intensive home care of middle-aged patients with severe heart failure results in improved quality of life and a decrease in hospital readmission rates.

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