United States Size Distribution and the Macroeconomy 1986–2009

Author(s):  
Lance Taylor ◽  
Armon Rezai ◽  
Rishabh Kumar ◽  
Nelson Barbosa ◽  
Laura Carvalho
1970 ◽  
Vol 8 (1) ◽  
pp. 78-81
Author(s):  
Shubham Prajapati ◽  
Sanjay Saha ◽  
B Shambulingappa ◽  
Dilip Kumar Ch. ◽  
Bikash Sahoo

Generic Nebulized aerosol is often perceived as inferior to their branded counterparts; however, they are safe and effective if they can meet the regulatory requirements. International regulatory agencies have developed recommendations and guidance for bioequivalence approaches of orally inhaled drug products (OIDPs) for local action. The objective of this article is to discuss the approaches can be used for to show bioequivalence requirement for Food and Drug Administration (FDA) in the United States of America (USA) with reference product. This review endorsed that inhalation solutions and suspensions undertaken to determine the drug substance delivery rate, total drug substance delivered and Aerodynamic assessment of nebulized aerosols [aerodynamic particle size distribution (APSD)/droplet size distribution (DSD)].These are the most important parameters in characterization, evaluation and bioequivalence studies of nebulizers. These devices operate continuously; once loaded and require little or no co-ordination on the part of user they proved that these devices suitable for weak, pediatric or geriatric patients. The regulatory agencies declared that; there is no specific requirements testing in case of nebulizers like Metered dose inhalers (MDI) and Dry powder inhalers (DPIs). In United States of America (USA) regulation falls under the auspices of centre for devices and radiological health (CDRH), and new devices require 510(k) premarket notification. This review outlines all the bioequivalence test parameter.  


1971 ◽  
Vol 49 (5) ◽  
pp. 591-597 ◽  
Author(s):  
J. D. Gregson

Studies on tick size, distribution, and hosts are made of two populations of Ixodes kingi Bishopp, the individuals of which appear to differ only in size. In Canada large specimens were collected only in Alberta and mainly from carnivores and ground squirrels, while small specimens were found only in British Columbia and mostly on pocket gophers and mice but occasionally on weasels. A study of available United States material revealed a similar pattern, the two populations being separated by the Rocky Mountains and the Wasatch Range, but each containing a scattered few specimens of intermediate size. It was shown that individuals of the two populations will interbreed and yield viable F2 larvae. It is suggested that the species is in a state of evolutionary divergence northwards.


1986 ◽  
Vol 46 (2) ◽  
pp. 463-475 ◽  
Author(s):  
Jeremy Atack

This paper investigates the impact of the emergence of large-scale enterprises on industrial structure in America in the mid-nineteenth century and concludes that their impact was ambiguous. In cottons and irons, average scale increased dramatically, but inequality in the size distribution of plants declined and economic concentration showed no clear trend. In other industries, changes in average scale were much smaller and inequality increased, but again there was no clear trend in concentration.


2010 ◽  
Vol 10 (16) ◽  
pp. 8065-8076 ◽  
Author(s):  
S. Hosseini ◽  
Q. Li ◽  
D. Cocker ◽  
D. Weise ◽  
A. Miller ◽  
...  

Abstract. Particle size distribution from biomass combustion is an important parameter as it affects air quality, climate modelling and health effects. To date, particle size distributions reported from prior studies vary not only due to difference in fuels but also difference in experimental conditions. This study aims to report characteristics of particle size distributions in well controlled repeatable lab scale biomass fires for southwestern United States fuels with focus on chaparral. The combustion laboratory at the United States Department of Agriculture-Forest Service's Fire Science Laboratory (USDA-FSL), Missoula, MT provided a repeatable combustion and dilution environment ideal for measurements. For a variety of fuels tested the major mode of particle size distribution was in the range of 29 to 52 nm, which is attributable to dilution of the fresh smoke. Comparing mass size distribution from FMPS and APS measurement 51–68% of particle mass was attributable to the particles ranging from 0.5 to 10 μm for PM10. Geometric mean diameter rapidly increased during flaming and gradually decreased during mixed and smoldering phase combustion. Most fuels produced a unimodal distribution during flaming phase and strong biomodal distribution during smoldering phase. The mode of combustion (flaming, mixed and smoldering) could be better distinguished using the slopes in MCE (Modified Combustion Efficiency) vs. geometric mean diameter than only using MCE values.


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