scholarly journals Multiple Sexual Partners as a Potential Independent Risk Factor for Cervical Cancer: a Meta-analysis of Epidemiological Studies

2015 ◽  
Vol 16 (9) ◽  
pp. 3893-3900 ◽  
Author(s):  
Zhi-Chang Liu ◽  
Wei-Dong Liu ◽  
Yan-Hui Liu ◽  
Xiao-Hua Ye ◽  
Si-Dong Chen
Keyword(s):  
Cervical Cancer ◽  
Risk Factor ◽  
Independent Risk Factor ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Sexual Partners ◽  
Multiple Sexual Partners

scholarly journals Sleep apnoea is a risk factor for severe COVID-19

2021 ◽  
Vol 8 (1) ◽  
pp. e000845
Author(s):  
Satu Strausz ◽  
Tuomo Kiiskinen ◽  
Martin Broberg ◽  
Sanni Ruotsalainen ◽  
Jukka Koskela ◽  
...  
Keyword(s):  
Risk Factor ◽  
Independent Risk Factor ◽  
Causes Of Death ◽  
Meta Analysis ◽  
Sleep Apnoea ◽  
Male Gender ◽  
Multivariate Logistic Regression Model ◽  
Multivariate Logistic Regression ◽  
Obstructive Sleep ◽  
Positive Controls

BackgroundObstructive sleep apnoea (OSA) is associated with higher body mass index (BMI), diabetes, older age and male gender, which are all risk factors for severe COVID-19.We aimed to study if OSA is an independent risk factor for COVID-19 infection or for severe COVID-19.MethodsOSA diagnosis and COVID-19 infection were extracted from the hospital discharge, causes of death and infectious diseases registries in individuals who participated in the FinnGen study (n=260 405). Severe COVID-19 was defined as COVID-19 requiring hospitalisation. Multivariate logistic regression model was used to examine association. Comorbidities for either COVID-19 or OSA were selected as covariates. We performed a meta-analysis with previous studies.ResultsWe identified 445 individuals with COVID-19, and 38 (8.5%) of them with OSA of whom 19 out of 91 (20.9%) were hospitalised. OSA associated with COVID-19 hospitalisation independent from age, sex, BMI and comorbidities (p-unadjusted=5.13×10−5, OR-adjusted=2.93 (95% CI 1.02 to 8.39), p-adjusted=0.045). OSA was not associated with the risk of contracting COVID-19 (p=0.25). A meta-analysis of OSA and severe COVID-19 showed association across 15 835 COVID-19 positive controls, and n=1294 patients with OSA with severe COVID-19 (OR=2.37 (95% 1.14 to 4.95), p=0.021).ConclusionRisk for contracting COVID-19 was the same for patients with OSA and those without OSA. In contrast, among COVID-19 positive patients, OSA was associated with higher risk for hospitalisation. Our findings are in line with earlier works and suggest OSA as an independent risk factor for severe COVID-19.

Is gestational diabetes mellitus an independent risk factor for macrosomia: a meta-analysis?

2014 ◽  
Vol 291 (4) ◽  
pp. 729-735 ◽  
Author(s):  
Xiu-Jie He ◽  
Feng-yun Qin ◽  
Chuan-Lai Hu ◽  
Meng Zhu ◽  
Chao-Qing Tian ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factor ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Independent Risk Factor ◽  
Meta Analysis

The 2 Gene Coding Sequence T807/A873 of the Platelet Collagen Receptor Integrin 2β1 Might Be a Genetic Risk Factor for the Development of Stroke in Younger Patients

Blood ◽  
1999 ◽  
Vol 93 (11) ◽  
pp. 3583-3586 ◽  
Author(s):  
Lena E. Carlsson ◽  
Sentot Santoso ◽  
Carsten Spitzer ◽  
Christof Kessler ◽  
Andreas Greinacher
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Independent Risk Factor ◽  
Epidemiological Studies ◽  
Receptor Expression ◽  
Stroke Patients ◽  
Younger Patients ◽  
Gene Coding ◽  
Collagen Receptor ◽  
Conventional Risk Factors

The polymorphisms C807T and G873A of the platelet integrin 2β1 (collagen receptor glycoprotein [GP] Ia-IIa) are linked to the expression density of this receptor. The GPIa T807/A873 allele causes a higher receptor expression, enhancing platelet binding to collagen. This might present a genetic predisposition for the development of thromboembolic complications. In this case-control study, the genotypes of the GPIa C807T polymorphism and presence of conventional risk factors (hypertension, diabetes mellitus, and smoking) were compared in stroke patients and patients without cerebrovascular disease (non-CVD patients) ≤50 years of age (n = 45 and 41, respectively) and in stroke patients and non-CVD patients more than 50 years of age (n = 182 and 129, respectively. In patients ≤50 years of age, the T807 allele was the only overrepresented variable (P = .023; odds ratio, 3.02; 95% confidence interval, 1.20 to 7.61) and an independent risk factor, whereas the presence of conventional risk factors was similar between stroke patients ≤50 years of age and non-CVD patients ≤50 years of age. Large epidemiological studies should prove whether the platelet collagen receptor GPIa-IIa T807 allele is an independent risk factor for the development of stroke in younger patients.

scholarly journals Morbid Obesity as an Independent Risk Factor for Disease-Specific Mortality in Women With Cervical Cancer

2014 ◽  
Vol 124 (6) ◽  
pp. 1098-1104 ◽  
Author(s):  
Michael Frumovitz ◽  
Anuja Jhingran ◽  
Pamela T. Soliman ◽  
Ann H. Klopp ◽  
Kathleen M. Schmeler ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Morbid Obesity ◽  
Risk Factor ◽  
Independent Risk Factor ◽  
Specific Mortality ◽  
Disease Specific Mortality ◽  
Disease Specific

Australian women's needs and preferences for information about human papillomavirus in cervical screening

2005 ◽  
Vol 12 (3) ◽  
pp. 134-141 ◽  
Author(s):  
Kirsten McCaffery ◽  
Les Irwig
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Information Needs ◽  
Pap Smear ◽  
Cervical Screening ◽  
Hpv Infection ◽  
Sexual Partners ◽  
Policy And Practice ◽  
Management Options ◽  
Multiple Sexual Partners

Objective: The role of human papillomavirus (HPV) in cervical cancer and developments in medical technology to prevent cervical cancer has changed information needs for women participating in cervical screening. Design: Qualitative face-to-face interviews were conducted with 19 women diagnosed with HPV infection on their Pap smear following routine cervical screening. Setting: Family planning clinics, general practice and specialist gynaecologist practices in Sydney and the surrounding area, Australia. Main outcome measures: Women's information needs, preferences and experiences of HPV diagnosis. Results: Women wanted further information on different HPV viral types, transmission, implications for sexual partners, prevalence, latency and regression of HPV, their management options and the implications of infection for cancer risk and fertility. Uncertainty about the key aspects of HPV, the style in which the clinician communicated the result and the mode of delivering the result (letter, telephone or consultation) influenced women's psychological response to the diagnosis of HPV. The delivery of results by letter alone was linked to considerable anxiety among the women interviewed. Women's experience of searching the Internet for further information about HPV was reported as difficult, anxiety provoking and contributing to the stigma of the infection because information was often located in the context of other sexually transmitted infections, with multiple sexual partners highlighted as a risk factor for infection. Conclusion: Women participating in cervical screening need high-quality information about HPV and its role in cervical cancer prior to screening rather than afterwards, when they face an abnormal result. The clinician potentially plays an important role in moderating the effects of diagnosis through the manner and mode in which an HPV diagnosis is delivered. Revision of cervical screening policy and practice in light of the changes in the understanding of HPV is recommended.

Birth Weight as a Risk Factor for Breast Cancer: A Meta-Analysis of 18 Epidemiological Studies

2009 ◽  
Vol 18 (8) ◽  
pp. 1169-1178 ◽  
Author(s):  
Xiaohui Xu ◽  
Amy B. Dailey ◽  
Mary Peoples-Sheps ◽  
Evelyn O. Talbott ◽  
Ning Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factor ◽  
Birth Weight ◽  
Meta Analysis ◽  
Epidemiological Studies

Pesticide exposure as a risk factor for amyotrophic lateral sclerosis: A meta-analysis of epidemiological studies

2012 ◽  
Vol 117 ◽  
pp. 112-119 ◽  
Author(s):  
Angela M. Malek ◽  
Aaron Barchowsky ◽  
Robert Bowser ◽  
Ada Youk ◽  
Evelyn O. Talbott
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Risk Factor ◽  
Pesticide Exposure ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Lateral Sclerosis

scholarly journals PEDIATRIC CLASSIFICATION AND EPIDEMIOLOGY OF ACUTE RENAL INJURY

2018 ◽  
Vol 63 (5) ◽  
pp. 36-42 ◽  
Author(s):  
N. D. Savenkova
Keyword(s):  
Risk Factor ◽  
Kidney Disease ◽  
Renal Injury ◽  
Independent Risk Factor ◽  
Systemic Disease ◽  
Pediatric Nephrology ◽  
Epidemiological Studies ◽  
Acute Renal Injury ◽  
Newborn Mortality

The article presents classification and epidemiology of acute renal injury in newborns and children. According to the international multicentre epidemiological studies, the development of acute renal injury is the main and independent risk factor of newborn mortality. Pediatric nephrology has discussed the evolution of the epidemiology of acute renal injury from primary kidney disease to the secondary one due to another systemic disease or its treatment in children.

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