Improvement in Polymyalgia Rheumatica Associated With Improved Control of Diabetes Mellitus: A Case Series

2020 ◽  
Author(s):  
Ken Yoshida ◽  
Noriko Sakamoto ◽  
Daitaro Kurosaka
Keyword(s):  
Diabetes Mellitus ◽  
Polymyalgia Rheumatica ◽  
Case Series ◽  
Control Of Diabetes

scholarly journals Tuberculosis and Diabetes Mellitus: A Case Series of 100 Patients

1970 ◽  
Vol 7 (2) ◽  
pp. 34-38 ◽  
Author(s):  
J Kishan ◽  
K Garg
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Case Series ◽  
Lower Lobe ◽  
Poor Control ◽  
Medical College ◽  
Uncontrolled Diabetes ◽  
History Of ◽  
Control Of Diabetes ◽  
Atypical Presentations

Introduction: Tuberculosis and Diabetes mellitus are two public health problems which not only often coexist but have serious implications on each other. DM has an impact on symptomatology, radiological presentation, diagnosis and management of TB. TB has a significant impact on DM, causing unmasking of DM and poor control because of stress or because of drug treatment for TB. Present study attempts to assess this coexistence with regard to the age predisposition, sex preponderance, duration and glycemic control of diabetes and the radiological presentations. Materials and Methods: 100 patients presenting to the Department of Tuberculosis and Chest Diseases, Government Medical College, Patiala, who were suffering from both Tuberculosis and Diabetes Mellitus, were studied. Various parameters considered included age, sex, history of diabetes with regard to the duration and the glycemic control and the radiological presentations. Results: It was found that majority were males (61/100). The age group most commonly involved was the 40-60year group (76/100). Majority had their Diabetes diagnosed before the diagnosis of Tuberculosis (57/100), 23 had diagnosis after TB diagnosis, and 20 simultaneously with TB diagnosis. Out of these 57 diagnosed diabetics, 11 patients had controlled diabetes whereas 46 (87.1%) had uncontrolled diabetes. 32 patients had the typical radiological lesions while 68 had atypical presentations with either lower lobe involvement, multi lobe involvement, cavitations or shadows fanning out from the hilum. Conclusion: TB and DM often coexist together and adversely effect each other. Both need to be managed properly in order to achieve favorable treatment outcome. Key Words: TB; DM DOI: 10.3126/saarctb.v7i2.4404SAARC J. TUBER. LUNG DIS. HIV/AIDS 2010 VII(2) 34-38

scholarly journals The Effect of HbA1c Variability as a Risk Measure for Microangiopathy in Type 1 Diabetes Mellitus

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1151
Author(s):  
Pedro Romero-Aroca ◽  
Raul Navarro-Gil ◽  
Albert Feliu ◽  
Aida Valls ◽  
Antonio Moreno ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Diabetic Retinopathy ◽  
Type 1 Diabetes Mellitus ◽  
Risk Measure ◽  
Case Series ◽  
Multivariate Statistical ◽  
Case Series Study ◽  
Prospective Case Series

Background: To measure the relationship between variability in HbA1c and microalbuminuria (MA) and diabetic retinopathy (DR) in the long term. Methods: A prospective case-series study, was conducted on 366 Type 1 Diabetes Mellitus patients with normoalbuminuria and without diabetic retinopathy at inclusion. The cohort was followed for a period of 12 years. The Cox survival analysis was used for the multivariate statistical study. The effect of variability in microangiopathy (retinopathy and nephropathy) was evaluated by calculating the standard deviation of HbA1c (SD-HbA1c), the coefficient of variation of HbA1c (CV-HbA1c), average real variability (ARV-HbA1c) and variability irrespective of the mean (VIM-HbA1c) adjusted for the other known variables. Results: A total of 106 patients developed diabetic retinopathy (29%) and 73 microalbuminuria (19.9%). Overt diabetic nephropathy, by our definition, affected only five patients (1.36%). Statistical results show that the current age, mean HbA1c, SD-HbA1c and ARV-HbA1c are significant in the development of diabetic retinopathy. Microalbuminuria was significant for current age, mean HbA1c, CV-HbA1c and ARV-HbA1c. Conclusions: By measuring the variability in HbA1c, we can use SD-HbA1c and ARV-HbA1c as possible targets for judging which patients are at risk of developing DR and MA, and CV-HbA1c as the target for severe DR.

TOLBUTAMIDE CONTROL OF DIABETES MELLITUS

The Lancet ◽  
1959 ◽  
Vol 274 (7104) ◽  
pp. 670
Author(s):  
I MURRAY
Keyword(s):  
Diabetes Mellitus ◽  
Control Of Diabetes

scholarly journals Polymyalgia rheumatica: A case series from Colombia and analysis of Latin America

2021 ◽  
pp. 100115
Author(s):  
Carlos Enrique Toro-Gutiérrez ◽  
Carlos A. Cañas ◽  
Rubén D. Mantilla ◽  
Santiago Beltrán ◽  
Vivian Pastrana-Gonzalez ◽  
...  
Keyword(s):  
Latin America ◽  
Polymyalgia Rheumatica ◽  
Case Series

Erythrocyte Insulin Binding in Insulin-Dependent Diabetes Mellitus: Lack of Relationship to Duration and Control of Diabetes in Children and Adolescents

PEDIATRICS ◽  
1980 ◽  
Vol 66 (3) ◽  
pp. 385-390
Author(s):  
Michael S. Kappy ◽  
Leslie P. Plotnick ◽  
Joann C. Findlay ◽  
Richard D. Kayne
Keyword(s):  
Diabetes Mellitus ◽  
Children And Adolescents ◽  
Insulin Dependent Diabetes Mellitus ◽  
Insulin Binding ◽  
Diabetic Control ◽  
Insulin Dependent Diabetes ◽  
Liver Fat ◽  
Dependent Diabetes Mellitus ◽  
Control Of Diabetes ◽  
Insulin Dependent

Insulin binding was measured in the erythrocytes (RBCs) of four children and 12 adolescents with insulin-dependent diabetes mellitus in the basal (fasting, nonketotic) state. Children and adolescents with insulin-dependent diabetes mellitus showed normal binding of insulin to their RBCs when expressed as the total insulin bound over the physiologic range of insulin concentrations. The insulin receptor concentration and receptor binding affinity for insulin were also normal. These parameters of insulin binding were not correlated with either the duration of diabetes or the degree of diabetic control in the patients. Since insulin binding by erythrocytes has been shown to reflect binding by traditional target tissues (liver, fat), the data suggest that alterations in binding of insulin to cells in children and adolescents with insulin-dependent diabetes mellitus probably play little, if any, role in the response of these patients to exogenous insulin or in the control of their glucose metabolism in the basal state.

Case series: COVID-19 infection causing new-onset diabetes mellitus?

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Rujuta Katkar ◽  
Narasa Raju Madam
Keyword(s):  
Diabetes Mellitus ◽  
Severe Acute Respiratory Syndrome ◽  
Cell Damage ◽  
Small Sample Size ◽  
Case Series ◽  
Small Sample ◽  
Onset Diabetes ◽  
History Of ◽  
New Onset Diabetes Mellitus ◽  
New Onset

Objectives: This paper seeks to explore the hypothesis of the potential diabetogenic effect of SARS-COV-2 (Severe Acute respiratory syndrome coronavirus). Case series presentation: We present a case series of observation among 8 patients of age group ranging from 34 to 74 years with a BMI range of 26.61 to 53.21 Kilogram/square meters that developed new-onset diabetes after COVID-19 infection. Severe Acute Respiratory Syndrome Coronavirus (SARS-COV-2), commonly known as Coronavirus or COVID-19(Coronavirus infectious disease), gains entry into the cells by binding to the Angiotensin-converting enzyme-2(ACE-2) receptors located in essential metabolic tissues including the pancreas, adipose tissue, small intestine, and kidneys. The evidence reviewed from the scientific literature describes how ACE 2 receptors play a role in the pathogenesis of diabetes and the plausible interaction of SARS-COV-2 with ACE 2 receptors in metabolic organs and tissues. Conclusion: The 8 patients without a past medical history of diabetes admitted with COVID-19 infection developed new-onset diabetes mellitus due to plausible interaction of SARS-COV-2 with ACE 2 receptors. The resulting downregulation of ACE-2 and ACE-2 receptors expression caused islet-cell damage resulting into diabetes. The resulting observation has the potential to adversely impact significant number of the globally affected population. Screening patients with COVID-19 for diabetes routinely can help in early detection, significantly reducing morbidity and mortality associated with diabetes. Due to limitations of observational study with a small sample size will require further investigation in the form of Clinical trial.

CASE SERIES: A SPECTRUM OF FUNGAL INFECTIONS IN COVID-19

2021 ◽  
pp. 29-30
Author(s):  
Venkatesh B. C. ◽  
Rajendra Rao K. M. ◽  
K. N. Mohan Rao
Keyword(s):  
Diabetes Mellitus ◽  
Fungal Infections ◽  
Virus Disease ◽  
Case Series ◽  
Health Crisis ◽  
Major Health ◽  
Corona Virus ◽  
Patients With Diabetes ◽  
Causative Agents

Corona virus Disease 2019 (COVID-19) pandemic is causing a major health crisis across the globe. With the increasing number of fungal infections associated with COVID-19 being reported, it is imperative to understand the spectrum of such infections. Most documented cases have been reported in patients with diabetes mellitus or treatment with immunomodulators. The most common causative agents are Aspergillus, Candida or Mucorales. This series aims to portray the spectrum of fungal infections associated with COVID-19.

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