scholarly journals Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis

eLife ◽  
2021 ◽  
Vol 10 ◽  
Author(s):  
Andrea Milzi ◽  
Enrico Domenico Lemma ◽  
Rosalia Dettori ◽  
Kathrin Burgmaier ◽  
Nikolaus Marx ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Vessel Wall ◽  
Plaque Rupture ◽  
Area Under The Curve ◽  
Stress Concentrations ◽  
Element Analysis ◽  
Biomechanical Stress ◽  
Fibrous Cap ◽  
Maximal Stress

Plaque rupture occurs if stress within coronary lesions exceeds the protection exerted by the fibrous cap overlying the necrotic lipid core. However, very little is known about the biomechanical stress exerting this disrupting force. Employing optical coherence tomography (OCT), we generated plaque models and performed finite-element analysis to simulate stress distributions within the vessel wall in 10 ruptured and 10 non-ruptured lesions. In ruptured lesions, maximal stress within fibrous cap (peak cap stress [PCS]: 174 ± 67 vs. 52 ± 42 kPa, p<0.001) and vessel wall (maximal plaque stress [MPS]: 399 ± 233 vs. 90 ± 95 kPa, p=0.001) were significantly higher compared to non-ruptured plaques. Ruptures arose in the immediate proximity of maximal stress concentrations (angular distances: 21.8 ± 30.3° for PCS vs. 20.7 ± 23.7° for MPS); stress concentrations excellently predicted plaque rupture (area under the curve: 0.940 for PCS, 0.950 for MPS). This prediction of plaque rupture was superior to established vulnerability features such as fibrous cap thickness or macrophage infiltration. In conclusion, OCT-based finite-element analysis effectively assesses plaque biomechanics, which in turn predicts plaque rupture in patients. This highlights the importance of morpho-mechanic analysis assessing the disrupting effects of plaque stress.

Practical Procedures for Technical and Economic Investigation of Ship Structural Details

1981 ◽  
Vol 18 (01) ◽  
pp. 51-68
Author(s):  
Donald Liu ◽  
Abram Bakker
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Stress Concentrations ◽  
Element Analysis ◽  
Analysis Techniques ◽  
Structural Problems ◽  
Analysis Technique ◽  
The Finite Element Analysis ◽  
Structural Details

Local structural problems in ships are generally the result of stress concentrations in structural details. The intent of this paper is to show that costly repairs and lay-up time of a vessel can often be prevented, if these problem areas are recognized and investigated in the design stages. Such investigations can be performed for minimal labor and computer costs by using finite-element analysis techniques. Practical procedures for analyzing structural details are presented, including discussions of the results and the analysis costs expended. It is shown that the application of the finite-element analysis technique can be economically employed in the investigation of structural details.

Mechanical Design, Additive Manufacturing, and Performance of Equal Volume Metamaterials

2021 ◽  
Author(s):  
Richárd Horváth ◽  
Vendel Barth ◽  
Viktor Gonda ◽  
Mihály Réger ◽  
Imre Felde
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Energy Absorption ◽  
Mechanical Design ◽  
Area Under The Curve ◽  
Cell Number ◽  
Element Analysis ◽  
Cross Sectional ◽  
Unit Cells ◽  
And Performance

Abstract In this paper, we study the energy absorption of metamaterials composed of unit cells whose special geometry makes the cross-sectional area and the volume of the bodies generated from them constant (for the same enclosing box dimensions). After a parametric description of such special geometries, we analyzed by finite element analysis the deformation of the metamaterials we have designed during compression. We 3D printed the designed metamaterials from plastic to subject them to real compression. The results of the finite element analysis were compared with the real compaction results. Then, for each test specimen, we plotted its compaction curve. By fitting a polynomial to the compaction curves and integrating it (area under the curve), the energy absorption of the samples can be obtained. As a result of these investigations, we drew a conclusion about the relationship between energy absorption and cell number.

Micro-scale finite element analysis of stress concentrations in steel fiber composites under transverse loading

2014 ◽  
Vol 49 (9) ◽  
pp. 1057-1069 ◽  
Author(s):  
Baris Sabuncuoglu ◽  
Svetlana Orlova ◽  
Larissa Gorbatikh ◽  
Stepan V Lomov ◽  
Ignaas Verpoest
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Steel Fiber ◽  
Fiber Composites ◽  
Transverse Loading ◽  
Stress Concentrations ◽  
Element Analysis ◽  
Micro Scale

scholarly journals Optimisation of Coating Properties for Fibre Optic Smart Structures using Finite Element Analysis

1994 ◽  
Vol 3 (5) ◽  
pp. 096369359400300
Author(s):  
M. Hadjiprocopiou ◽  
G.T. Reed ◽  
L. Hollaway ◽  
A.M. Thorne
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Optical Fibre ◽  
Smart Material ◽  
Material System ◽  
Careful Selection ◽  
Coating Properties ◽  
Stress Concentrations ◽  
Element Analysis ◽  
Selection Of

Finite Element analysis is used to determine and to minimise the stress concentrations which arise in a “Smart” material system due to the embedded optical fibre sensors. The FE results show that with careful selection of the coating stiffness and thickness the stress concentrations caused by the fibre inclusion in the host material can be reduced.

Finite Element Analysis of a Locked Bolt With an Initial Crack

2009 ◽  
Author(s):  
Jean Paul Kabche ◽  
Mauri´cio Rangel Pacheco ◽  
Ivan Thesi ◽  
Luiz Carlos Largura
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Operating Conditions ◽  
Material Behavior ◽  
Isotropic Hardening ◽  
Stress Concentrations ◽  
Engineering Structures ◽  
Element Analysis ◽  
Micro Cracks ◽  
Non Linear

Bolted connections are largely employed in various types of engineering structures to transfer loads from one member to another. In particular, the off-shore industry has made extensive use of these connections, predominantly at the sub-sea level. In spite of their advantages, bolted joints are critical regions and may become sources of structural weakness due to large stress concentrations. Under severe operating conditions, micro-cracks can develop in the bolt, creating regions of elevated stress which may significantly reduce the integrity of the connection and ultimately lead to failure. This paper presents the three-dimensional finite element analysis of a steel locked bolt assembly aimed to assess the effect of micro-cracks on the structural integrity of the assembly using the commercial finite element package ANSYS. Non-linear contact between the bolt and nut threads is considered, where frictional sliding between components is allowed. A bi-linear isotropic hardening model is used to account for non-linear material behavior. The assembly is loaded by applying a pre-load of fifty percent of the yield stress of the material, according to the API-6A Norm. Two geometric models are investigated: a healthy locked bolt assembly with no initial cracks; and a damaged model, where a circular crack is introduced at the root of the bolt threads. The effect of the crack size is studied by modeling the crack with three different radius sizes. The J-Integral fracture mechanics methodology was used to study the stress concentrations in the damaged model.

Improvement and FEA of New Type of Osteointegrated Implant for Higher Amputated Leg Attachment

2007 ◽  
Vol 342-343 ◽  
pp. 829-832
Author(s):  
J.M. Luo ◽  
L. Zheng ◽  
X.H. Shi ◽  
Yao Wu ◽  
Xing Dong Zhang
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Distal Part ◽  
Element Analysis ◽  
Bone Stress ◽  
Traditional Design ◽  
Maximal Stress ◽  
New Type ◽  
Scan Data ◽  
Leg Prosthesis

Stress concentration is one of the main mechanical problems leading to the failure of clinical application for osteointegrated implant of percutaneous osteointegrated prosthesis, which is especially marked for higher amputated leg prosthesis. Traditionally design was composed of only the distal part. To improve the biomechanical safety, a new design with the lag part similar to the lag screw was introduced. Based on CT scan data, relatively accurate model of femur for finite element analysis (FEA) were obtained. The FEA results with the new implant demonstrated that compared to traditional design, the declination of bone stress peak ranged from 15.68% to 28.67%, perpendicular deformation from 34.73% to 72.16%, and maximal stress of implant from 14.51% to 23.36% with the increasing of loads from 3750N to 2000N. So the new design of osteointegrated implant would be more secure mechanically, in the case of higher amputated leg attachment.

Structural analysis of a cross car beam using finite element models

2015 ◽  
Vol 6 (6) ◽  
pp. 759-774
Author(s):  
André F. B. P. Pinto ◽  
S.M.O. Tavares ◽  
José M. A. César de Sá ◽  
P.M.S.T. de Castro
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Modal Analysis ◽  
Mass Production ◽  
Experimental Testing ◽  
Stress Concentrations ◽  
Element Analysis ◽  
Content Type ◽  
Explicit Finite Element ◽  
Simulation Results

Purpose – The purpose of this paper is to use PAM-CRASH, a finite element analysis solver, to assess the performance of a mass production vehicle cross car beam (CCB) under an overlap frontal crash scenario (crashworthiness). Simulation results were reviewed according to what is plausible to register regarding some critical points displacements and, moreover, to identify its stress concentrations zones. Furthermore, it was also computed the CCB modal analysis (noise, vibration and harshness (NVH) assessment) in order to examine if its natural modes are within with the original equipment manufacturer (OEM) design targets. Design/methodology/approach – The available data at the beginning of the present study consisted of the structure CAD file and performance requirements stated by the OEM for NVH. No technical information was available concerning crashworthiness. Taking into account these limitations, it was decided to adapt the requirements for other mass production cars of the same category, as regards dynamic loading. A dynamic explicit code finite element analysis was performed throughout the CCB structure simulating the 120e−3 s crash event. For the modal analysis, there were some necessary modifications to the explicit finite element model in order to perform the analysis in implicit code. In addition, the car body in white stiffness was assigned at the boundaries. These stiffness values are withdrawn from the points where the CCB is attached to the car body’s sheet metal components. Findings – Although the unavailability of published results for this particular CCB model prevents a comparison of the present results, the trends and order of magnitude of the crash simulation results are within the expectations for this type of product. Concerning modal analysis, the steering column first natural frequency has a percent deviation from the design lower bound value of 5.09 percent when local body stiffness is considered and of 1.94 percent with fixed boundary conditions. The other requirement of the NVH assessment regarding a 5 Hz minimum interval between first vehicle CCB mode and the first mode of the steering column was indeed achieved with both boundary configurations. Originality/value – This study is a further confirmation of the interest of numerical modeling as a first step before actual experimental testing, saving time and money in an automotive industry that has seen an enormous increase of the demand for new car models in the last decade.

scholarly journals Three-Dimensional Finite Element Analysis to Evaluate Stress Distribution in Tooth and Implant-Supported Fixed Partial Denture–An In Vitro Study

2020 ◽  
Vol 8 (03) ◽  
pp. 084-091
Author(s):  
Himani Jain ◽  
Tarun Kalra ◽  
Manjit Kumar ◽  
Ajay Bansal ◽  
Deepti Jain
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Stress Distribution ◽  
Alveolar Bone ◽  
Three Dimensional ◽  
In Vitro Study ◽  
Stress Concentrations ◽  
Element Analysis ◽  
Three Dimensional Finite Element

Abstract Introduction This study was undertaken to assess the influence of different superstructure materials, when subjected to occlusal loading, on the pattern of stress distribution in tooth-supported, implant-supported, and tooth implant-supported fixed partial prostheses, using the finite element analysis with a comparative viewpoint. Materials and Methods The geometric models of implant and mandibular bone were generated. Three models were created in accordance with the need of the study. The first model was given a tooth-supported fixed partial prosthesis. The second model was given tooth implant-supported fixed partial prosthesis, and the third model was given implant-supported fixed partial prosthesis. Forces of 100 N and 50 N were applied axially and buccolingually, respectively. Results The present study compared the stresses arising in the natural tooth, implant, and the whole prostheses under simulated axial and buccolingual loading of three types of fixed partial dentures, namely, tooth-supported, tooth implant-supported, and implant-supported fixed partial dental prostheses using three different types of materials. Conclusion The pattern of stress distribution did not appear to be significantly affected by the type of prosthesis materials in all models. The maximum stress concentrations were found in the alveolar bone around the neck of the teeth and implants.

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