scholarly journals Magnitude of non-adherence to antiretroviral therapy and associated factors among adult people living with HIV/AIDS in Benishangul-Gumuz Regional State, Ethiopia

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e8558
Author(s):  
Fikadu Tadesse Nigusso ◽  
Azwihangwisi Helen Mavhandu-Mudzusi

Introduction Following global efforts to increase antiretroviral therapy (ART) access and coverage, Ethiopia has made significant achievement with a 6.3% annual decline in the HIV/AIDS incidence rate between 1990 and 2016. Such success depends not only on access to ART but also on attaining optimum treatment adherence. Emerging studies in Ethiopia has shown the increasing prevalence of poor adherence and lack of the desired viral suppression, but the extent and factors associated with non-adherence to ART are not well known, especially in the current study setup. In this study, we examined the magnitude and factors associated with treatment and non-adherence to ART among people living with HIV in Benishangul-Gumuz Regional State, northwest Ethiopia. Methods An institutional facility based cross-sectional descriptive study was carried out among adult people living with HIV/AIDS from mid-December 2016 to February 2017 with only 98.9% response rate. Sociodemographic factors (age, gender, marital status and residential area), economic factors (educational status, income, asset possession, employment status, dietary diversity, nutritional status and food security), and clinical characteristics (CD4 count, duration on ART and history of opportunistic infections) were explanatory variables. ART non-adherence was measured using a visual analogue scale (VAS). We used binary logistic regression and subsequent multivariate logistic regression analysis to determine the factors associated with ART non-adherence. Result Overall, 39.7% of the participants were found non-adherent to ART. Strong association was found between non-adherence to ART and young age below 25 years (AOR: 4.30, 95% CI [1.39–3.35]; p = 0.011), urban residential area (AOR: 2.78, CI [1.23–7.09], p = 0.043), lack of employment (AOR: 1.75, 95% CI [1.05–2.91], p = 0.032), food insecurity (AOR: 2.67, 95% CI [7.59–8.97]; p < 0.0001), malnutrition (AOR: 1.55, 95% CI [1.94–2.56]; p = 0.027) and opportunistic infections (AOR: 1.81, 95% CI [1.11–2.97]; p = 0.018). Conclusion The prevalence of non-adherence to ART in this study was high. Sociodemographic and economic factors such as young age of below 25 years, urban residential area, lack of employment, food insecurity, malnutrition and opportunistic infections were among the factors associated with non-adherence to ART.

2021 ◽  
Vol 38 ◽  
Author(s):  
Gloria Lubega ◽  
Billy Mayanja ◽  
Joseph Lutaakome ◽  
Andrew Abaasa ◽  
Rebecca Thomson ◽  
...  

2020 ◽  
Vol 24 (1) ◽  
pp. 65-72 ◽  
Author(s):  
Larissa Negromonte Azevedo ◽  
Ricardo Arraes de Alencar Ximenes ◽  
Polyana Monteiro ◽  
Ulisses Ramos Montarroyos ◽  
Demócrito de Barros Miranda-Filho

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yi Li ◽  
Xiao-Wen Zhang ◽  
Bin Liao ◽  
Jun Liang ◽  
Wen-Jie He ◽  
...  

Abstract Background People living with HIV/AIDS not only require effective treatment for the alleviation of physical discomfort but also require social support to help them address difficulties in life and relieve their psychological anxiety and uneasiness. The social support network is of tremendous importance in helping people living with HIV/AIDS maintain good physical and mental health. This study aims to analyse the social support status among people living with HIV/AIDS in Kunming and explore associated factors. Method The Social Support Rating Scale (SSRS) was used, and a questionnaire survey was conducted using convenience sampling to select people living with HIV/AIDS from 14 counties of Kunming. It collected information on general demographic information and social support status. Univariate and multivariate linear regression models were used to explore the associated factors. Results A total of 990 valid questionnaires were completed. Data from all participants were analysed. Univariate analysis suggested that the factors associated with social support may include marital status, monthly income, and antiretroviral therapy. On the other hand, factors including monthly income and antiretroviral therapy accounted for the social support total score in the multivariate analysis. Conclusion Social support among people living with HIV/AIDS in Kunming was generally low. This study identified a number of factors associated with social support among people living with HIV/AIDS. Based on our findings, appropriate interventions should be introduced to provide social support for those living with HIV/AIDS.


2020 ◽  
Author(s):  
Binyam Tariku Seboka ◽  
Samuel Hailegebreal ◽  
Delelegn Emwodew Yehualashet ◽  
Abel Desalegn Demeke

Abstract Background: HIV is a major public health concern in many developing countries. HIV related discriminatory attitudes or stigmas considered as a key in the prevention and control of HIV prevalence. This work evaluated the overall attitude of the population towards people living with HIV (PLHIV) in Ethiopia, which helps in the prevention and control of HIV/AIDS. Methods: Secondary data was obtained from the 2016 Ethiopian Demographic and Health Survey. Data included 20,770 samples of women and men between the ages of 15 to 49 years, which is a nationally representative sample in Ethiopia. Analytical methods used in this paper include descriptive analysis and multivariate logistic regression to identify factors associated with discriminatory attitudes .Results: A total of 20,770 samples who have heard about HIV/AIDS were included in the analysis. Out of this, 41% of respondents said they would not buy fresh vegetables from vendor and 34.1% of them indicated HIV positive children should not attend school with HIV negative children. Multivariate Logistic regression results indicated having discriminatory attitudes were associated with the lack of knowledge of HIV/AIDS prevention methods, endorsement transmission misconceptions, and never have been tested for HIV. Furthermore, respondents reside in rural areas, lack of formal education, belonging to poor wealth quantile, and lack of media exposure shows a higher level of discriminatory attitudes.Conclusion: The findings of this research showed a high magnitude of stigma towards people living with HIV/AIDS among reproductive age women and men in Ethiopia. For stigma and discriminatory attitudes to be decreased interventions should focused on improving HIV related knowledge’s through mass medias such as television and newspapers, especially through medias that can address the rural community.


2019 ◽  
Vol 18 (1) ◽  
pp. 43-50
Author(s):  
Nirmala Aryal ◽  
Radha Paudel ◽  
Sarita Adhikari ◽  
Aruna Rai

Introduction: AIDS and STD is prioritised disease control program of Nepal. Successful treatment of HIV positive patient is fundamental to control the progression to AIDS and ART adherence is crucial for successful treatment. The objective of the study was to find out the factors associated with adherence to antiretroviral therapy among people living with HIV/AIDS. Methods: Descriptive cross sectional research design was adopted. A total of 195 people living with HIV who were above the age 18 years and taking ARV therapy for at least six months from the ART centre of Sukraraj Tropical and Infectious Disease Hospital were selected by using purposive sampling technique. Data was collected using interview technique with semi structured questionnaire. Collected data was analysed using descriptive and inferential statistics. Results: The findings showed that 91.28% of the respondents reported perfect adherence (≥95%) and 8.71% of the respondents reported non- adherence. Age (OR: 4.28; CI 1.00-18.26) and marital status (OR: 4.96; CI 1.67-14.75) were the socio-demographic factors associated with adherence to ARV therapy. Number of tablets per day (OR: 10.72; CI 1.21-94.4) and use of reminders tool (OR:11.14; CI 2.35-52.75) were the patient related factors significantly associated with the adherence to ARV therapy. Likewise, experience of no discrimination (OR 3.90; CI 1.11-13.69) and help for the intake of medicine from family members (OR 2.95; CI 1.95-9.19) were the psychosocial factors significantly associated with adherence to ARV therapy. Adherence counselling (OR 13.38; CI 2.99-59.75) and lower travelling cost (OR 3.99; CI 1.40-11.34) were the service factors significantly associated with adherence to ARV therapy. Conclusions: The prevalence of adherence found in this study was good. Help from the family members, adherence counselling and use of reminders tool for intake of medicine enhanced adherence. Whereas, side effects, alcohol use, burden of pills, experience of discrimination were the barriers for adherence to ART. For improving adherence government and as well as the hospital requires interventions which recognise these barriers.  


2020 ◽  
Author(s):  
Yi Li ◽  
Xiao Wen Zhang ◽  
Bin Liao ◽  
Jun Liang ◽  
Wen Jie He ◽  
...  

Abstract Background: People living with HIV/AIDS not only require effective treatment for the alleviation of physical discomfort but also require social support to help them address difficulties in life and relieve their psychological anxiety and uneasiness. The social support network is of tremendous importance in helping people living with HIV/AIDS maintain good physical and mental health. This study aims to analyse the social support status among people living with HIV/AIDS in Kunming and explore associated factors.Method: The Social Support Rating Scale (SSRS) was used, and a questionnaire survey was conducted using convenience sampling to select people living with HIV/AIDS from 14 counties of Kunming. It collected information on general demographic information and social support status. Univariate and multivariate linear regression models were used to explore the associated factors.Results: A total of 990 valid questionnaires were completed. Data from all participants were analysed. Univariate analysis suggested that the factors associated with social support may include marital status, monthly income, and antiretroviral therapy. On the other hand, factors including monthly income and antiretroviral therapy accounted for the social support total score in the multivariate analysis.Conclusion: Social support among people living with HIV/AIDS in Kunming was generally low. This study identified a number of factors associated with social support among people living with HIV/AIDS. Based on our findings, appropriate interventions should be introduced to provide social support for those living with HIV/AIDS.


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