scholarly journals Protective and Therapeutic Effects of Aloe Vera Gel on Ulcerative Colitis Induced by Acetic Acid in Rats

2020 ◽  
Vol 9 (3) ◽  
pp. 223
Author(s):  
Gholamreza Bahrami ◽  
Hossein Malekshahi ◽  
Shahram Miraghaee ◽  
Hamid Madani ◽  
Atefeh Babaei ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Acetic Acid ◽  
Aloe Vera ◽  
Therapeutic Effects ◽  
Aloe Vera Gel

scholarly journals The Healing Effect of Aloe Vera Gel on Acetic Acid-Induced Ulcerative Colitis in Rat

2020 ◽  
Vol 12 (3) ◽  
pp. 154-161 ◽  
Author(s):  
Negar Hassanshahi ◽  
Seyed Jalil Masoumi ◽  
Davood Mehrabani ◽  
Seyedeh Sara Hashemi ◽  
Morteza Zare
Keyword(s):  
Ulcerative Colitis ◽  
Acetic Acid ◽  
Mrna Expression ◽  
Aloe Vera ◽  
Control Group ◽  
Therapeutic Effects ◽  
Inflammatory Disorder ◽  
Colon Tissue ◽  
Aloe Vera Gel ◽  
Oral Form

BACKGROUND The use of herbal and synthetic compounds can be effective in improving the areas and repair of tissues that have been affected during the processes like what happens in ulcerative colitis (UC) as a common inflammatory disorder. According to the beneficial effects of aloe vera, in this study, we aimed to assess the therapeutic effects of oral aloe vera gel on acetic acid-induced colitis in rats by histopathological and molecular analysis of Bax, and BCL-2 genes expression (using RT-PCR technique) in colon tissue samples. METHODS This experimental study comprised 32 adult male Sprague Dawley rats weighting 220 ± 20 g that were randomly divided into four groups as follows. The control group (healthy rats), colitis group in which UC was induced by transrectal administration of 3% acetic acid with no treatment, oral form of sulfasalazine group in which UC was induced by transrectal administration of 3% acetic acid, then was treated by oral administration of sulfasalazine 500 mg/kg body weight, and the fourth group which received oral form of aloe vera gel (200 mg / kg) for 21 days, respectively after induction of UC. Then, the therapeutic effects of treatment groups were compared with the control group and the colitis group with no treatment, by the assessment of histopathological and molecular changes in the colon tissues of rats on the 7th, 14th, and 21st days. Finally, the collected data were analyzed using statistical tests. RESULTS Histologically, aloe vera gel treatment could reduce and heal colon tissue damages in induced colitis. Also, this gel reduced apoptosis in rat’s colon with acetic acid-induced colitis, which showed in significantly decreased in Bax mRNA expression and significantly increased BCL-2 mRNA expression compared with the colitis group with no treatment. CONCLUSION Aloe vera gel has a significant effect on the treatment of UC in rat because of the beneficial effect that was found from aloe vera such as decreasing the severity of colitis as evidenced by histopathological findings, and with respect to apoptosis and gene expression that were related to wound healing process, and suppression of the elevation of Bax mRNA with the upregulation of Bcl-2, which can be considered effective in the treatment of UC.

scholarly journals Therapeutic Effects of Pure Aloe Vera Gel on Alloxan‐Induced Diabetic animal models.

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Ngozi Imaga ◽  
G Obominiru ◽  
O Oyadina ◽  
uzoma okafor
Keyword(s):  
Animal Models ◽  
Aloe Vera ◽  
Diabetic Animal ◽  
Therapeutic Effects ◽  
Aloe Vera Gel

scholarly journals Therapeutic Effects of Momordica charantia L. Ethanolic Extract on Acetic Acid-Induced Ulcerative Colitis in Rats

2021 ◽  
Vol 0 (0) ◽  
pp. 119-128
Author(s):  
Dilek Özbeyli ◽  
Ali Şen ◽  
Aslı Aykaç ◽  
Kerem Teralı ◽  
Özlem Çilingir Kaya ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Acetic Acid ◽  
Ethanolic Extract ◽  
Momordica Charantia ◽  
Therapeutic Effects

scholarly journals Comparison of therapeutic effects of encapsulated Mesenchymal stem cells in Aloe vera gel and Chitosan-based gel in healing of grade-II burn injuries

2021 ◽  
Vol 18 ◽  
pp. 30-37
Author(s):  
Esmaeel Sharifi ◽  
Mohammad Chehelgerdi ◽  
Ali Fatahian-Kelishadrokhi ◽  
Farshad Yazdani-Nafchi ◽  
Korosh Ashrafi-Dehkordi
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Aloe Vera ◽  
Burn Injuries ◽  
Therapeutic Effects ◽  
Aloe Vera Gel ◽  
Grade Ii

scholarly journals TEKNOLOGI PENANGANAN BUAH SEGAR STROBERI UNTUK MEMPERTAHANKAN MUTU / Fresh Handling Techniques for Strawberry to Maintain its Quality

2019 ◽  
Vol 38 (1) ◽  
pp. 47
Author(s):  
Ermi Sukasih ◽  
Setyadjit Setyadjit
Keyword(s):  
Acetic Acid ◽  
Storage Temperature ◽  
Aloe Vera ◽  
Oxide Coating ◽  
Quality Standards ◽  
Added Value ◽  
Strawberry Fruit ◽  
Aloe Vera Gel ◽  
Handling Quality

<p>Strawberries (Fragaria sp.) are mostly grown in the mountainy areas in Indonesia and need a long transportation to get to the consumers. Long transportation will cause more than 50% damage to strawberries due to decay. Handling procedures need to be good and proper from farmer to the consumer or processor customer so that fruit reach destination in expected condition. Handling was done during pre-harvest and postharvest so that the quality of fresh strawberry fruit can be preserved. The technology for handling strawberry fruits that already exists includes: pre-harvest by spraying with antimicrobial agent, postharvest include for collecting, sorting and grading, washing, dipping with calcium chloride or naphtalene acetic acid, waxing, fumigation with nitric oxide, coating with chitosan or aloe vera gel combined with glycerol, irradiation, packaging, storage and transportation. The recommended storage temperature for strawberries is at 4oC, it can extend the shelf life of strawberries up to 1011 days with the best chemical characteristics. Implementing of SNI to strawberries in Indonesia to increase product competitiveness and increase added value still needs intensive efforts. 1.The classification and quality standards of strawberries can refer to the SNI No. 8026, 2014 and the Commission Implementing Regulation (2011).</p><p>Keywords: Strawberry, preharvest, postharvest, fresh handling, quality</p><p> </p><p><strong>Abstrak</strong></p><p>Di Indonesia, stroberi (Fragaria sp.) umumnya tumbuh di daerah pegunungan sehingga memiliki risiko tinggi dalam transportasi ke konsumen. Kerusakan stroberi karena perjalanan yang lama dapat mengakibatkan kerusakan buah lebih dari 50% akibat pembusukan. Penanganan yang baik dan benar diperlukan agar buah tetap dalam keadaan segar sampai ke tangan konsumen, sesuai dengan standar yang berlaku. Buah stroberi perlu ditangani dengan baik sejak prapanen hingga pascapanen agar kesegaran buah dapat dipertahankan. Teknologi penanganan stroberi yang telah dihasilkan meliputi: (1) pada saat prapanen adalah penyemprotan menggunakan antimikroba, (2) pada saat pascapanen pengumpulan buah secara hati-hati, sortasi dan grading, pencucian, pencelupan dengan kalsium klorida atau Naphtalene Acetic Acid, pelilinan, fumigasi dengan nitrit oksida, pelapisan dengan kitosan, gel lidah buaya yang dikombinasikan dengan gliserol, iradiasi, pengemasan, penyimpanan, dan pengangkutan. Penyimpanan buah stroberi pada suhu 4oC dapat memperpanjang umur simpan buah hingga 10-11 hari dengan karakteristik kimiawi terbaik. Penerapan SNI buah stroberi di Indonesia masih perlu diupayakan lebih intensif untuk meningkatkan daya saing produk dan meningkatkan nilai tambah. Klasifikasi dan standar mutu buah stroberi dapat mengacu pada SNI No 8026 Tahun 2014 dan Commission Implementing Regulation (2011).</p><p>Kata kunci: Stroberi, prapanen, pascapanen, penanganan segar, mutu</p>

scholarly journals Randomized, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis

2004 ◽  
Vol 19 (7) ◽  
pp. 739-747 ◽  
Author(s):  
L. Langmead ◽  
R. M. Feakins ◽  
S. Goldthorpe ◽  
H. Holt ◽  
E. Tsironi ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Controlled Trial ◽  
Aloe Vera ◽  
Active Ulcerative Colitis ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Aloe Vera Gel
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