scholarly journals Diabetic Peripheral Neuropathy and its Association with Diabetes Self-care: A Clinic-based Study in an Urban Health Centre, Kolkata

2021 ◽  
Author(s):  
Mukesh Kumar ◽  
Bobby Paul ◽  
Aparajita Dasgupta ◽  
Lina Bandyopadhyay ◽  
Soumit Roy ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Peripheral Neuropathy ◽  
Scale Score ◽  
Urban Health ◽  
Diabetic Peripheral Neuropathy ◽  
West Bengal ◽  
Self Care ◽  
Self Management ◽  
Health Clinic ◽  
Training Centre

Introduction: Diabetes mellitus is considered as silent epidemic worldwide including India. Peripheral neuropathy is one of the most common complications of diabetes mellitus. Diabetes Self-Management (DSM) is crucial in mitigating the afflictions of diabetes and it’s after effects. There was dearth of studies in view of Diabetic Peripheral Neuropathy (DPN) and diabetes self-management in Kolkata, West Bengal. Aim: To assess the associations between diabetes self-management and DPN in Type 2 Diabetes Mellitus (T2DM) patients attending an urban health clinic in Kolkata. Materials and Methods: This study was conducted from December 2018 to March 2019 among known case of T2DM patients aged 30 years and above attending the Non-Communicable Disease (NCD) clinic at Chetla, under the purview of field practice areas of Urban Health Unit and Training centre (UHU and TC) of All India Institute of Hygiene and Public Health (AIIH and PH) Kolkata, West Bengal. A pre-designed and pre-tested schedule was used to collect data which were analysed using International Business Machines Statistical Product and Service Solutions (IBM SPSS) version 16.0 and represented using various tables. Results: The mean (SD) age of the participants was 54.89 (8.98) years. About 32.4% of the patients had DPN which was significantly associated with increased duration of T2DM {AOR (95% CI)}={1.52 (1.22-1.91)}, lower glucose management sub-scale score {AOR (95% CI)}={2.84 (1.42-5.67)} and lower healthcare use sub-scale score {AOR (95% CI)}={1.86 (1.05-3.31)}. Conclusion: Early screening and education regarding diabetes self-care would be helpful in glycaemic control and in prevention of DPN.

Text Messaging to Improve Disease Management in Patients With Painful Diabetic Peripheral Neuropathy

2018 ◽  
Vol 44 (3) ◽  
pp. 237-248 ◽  
Author(s):  
Victoria Bauer ◽  
Nancy Goodman ◽  
Brittany Lapin ◽  
Camille Cooley ◽  
Ed Wang ◽  
...  
Keyword(s):  
Peripheral Neuropathy ◽  
Usual Care ◽  
Health Beliefs ◽  
Diabetic Peripheral Neuropathy ◽  
Text Messaging ◽  
Self Care ◽  
Text Messages ◽  
Self Management ◽  
Painful Diabetic Peripheral Neuropathy ◽  
The Impact

Purpose The purpose of the study was to determine the impact of educational text messages on diabetes self-management activities and outcomes in patients with painful diabetic peripheral neuropathy (pDPN). Methods Patients with pDPN identified from a large integrated health system who agreed to participate were randomized to 6 months of usual care (UC) or UC plus twice-daily diabetes self-management text messages (UC+TxtM). Outcomes included the Pain Numerical Rating Scale, Summary of Diabetes Self-Care Activities (SDSCA), questions on diabetes health beliefs, and glycated hemoglobin (A1C). Changes from baseline were evaluated at 6 months and compared between groups. Results Demographic characteristics were balanced between groups (N = 62; 53% female, mean age = 63 years, 94% type 2 diabetes), as were baseline measures. After 6 months, pain decreased with UC+TxtM from 6.3 to 5.5 and with UC from 6.5 to 6.0, with no difference between groups. UC+TxtM but not UC was associated with significant improvements from baseline on all SDSCA subscales. On diabetes health beliefs, UC+TxtM patients reported significantly increased benefits and reduced barriers and susceptibility relative to UC at 6 months. A1C declined in both groups, but neither change was significant relative to baseline. Conclusions Patients with pDPN who receive twice-daily text messages regarding diabetes management reported reduced pain relative to baseline, although this change was not significant compared with usual care. In addition, text messaging was associated with increased self-management activities and improved diabetes health beliefs and total self-care. These results warrant further investigation.

scholarly journals Albumin-Creatinine Ratio is More Diagnostic Sensitive than Cystatin-C in Assessment of Diabetic Peripheral Neuropathy

2018 ◽  
Vol 1 (3) ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Peripheral Neuropathy ◽  
Cystatin C ◽  
Early Treatment ◽  
Diabetic Peripheral Neuropathy ◽  
Diabetic Patients ◽  
Creatinine Ratio ◽  
Serum Cystatin C ◽  
Albumin Creatinine Ratio

Background: Diabetic Peripheral neuropathy is one of the most common cardiovascular complications among diabetes mellitus patients and occurs in more than half of the population of diabetic patients world-wide. It is a common cause of foot ulcer, gangrene and amputation among diabetics. Thus, its prevention or early treatment can improve the quality of life of diabetic patients. In a bid to reduce it, various biochemical markers have been evaluated to enable early treatment and amelioration of diabetic neuropathy among diabetes mellitus patients. Aim: Evaluation of the diagnostic relevance of Cystatin-C versus Albumin-creatinine ratio in assessment of Peripheral neuropathy in diabetic type 2 subjects. Method: 102 type 2 DM subjects (66 females and 36 males) and 100 control subjects of same age range (40 – 80 years) were recruited for this study which includes 51 subjects with peripheral neuropathy and 51 subjects without peripheral neuropathy. Serum Cystatin-C, Microalbuminuria, Urine creatinine and HBA1c were analysed with standard methods. Results: Cystatin-C, Microalbuminuria, Albumin-creatinine ratio and Glycated haemoglobin were significantly elevated (P<0.05) in diabetic subjects compared to the control. Cystatin-C (ng/ml), microalbuminuria (mg/l), albumin creatinine ratio (mg/mmol) and HBA1c (%) is [105.52 ± 45.11; 90.07±20.29; 10.48 ± 4.82; 6.9±1.7] respectively. Microalbuminuria, albumin creatinine ratio showed significant increase (P<0.05) in subjects with peripheral neuropathy compared to those subjects without [92.11± 22.82; 35.70±16.35; 2.61±1.1; 6.38±1.79]. The ROC curve shows that Albumin-creatinine ratio showed significant (P<0.05) sensitivity to peripheral neuropathy [AUC=0.714] while Cystatin-C showed no significant (P<0.05) sensitivity to peripheral neuropathy complication [AUC=0.553]. Conclusion: Cystatin-C was found to be deranged in diabetics. However, Albumin-creatinine ratio showed more diagnostic sensitivity for peripheral neuropathy than Cystatin-C.

scholarly journals The Effect of Cognitive Behavioral Therapy on Self-Management and Self-Care Behaviors of Type 2 Diabetes Mellitus Patients

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Jenny Marlindawani Purba ◽  
Hanna Ester Empraninta
Keyword(s):  
Diabetes Mellitus ◽  
Cognitive Behavioral Therapy ◽  
Behavior Therapy ◽  
Cognitive Behavior Therapy ◽  
Behavioral Therapy ◽  
Self Care ◽  
Self Management ◽  
Cognitive Behavior ◽  
Type 2 Dm

<p><em>Diabetes mellitus (DM) is the condition of metabolism affected by chronic hyperglycemia (the increase of glucose levels in the blood) caused by insulin secretion defect. One of the non-pharmacological therapies used to decrease the type 2 DM is cognitive behavioral therapy. The objective of the research was to identify the effect of Cognitive Behavior Therapy (CBT) on self management and self-care behaviors of type 2 DM patients. The research used a quasi-experimental method with a two</em><em>-</em><em>group pretest-posttest design. The samples were 70 respondents with 35 of them were in the intervention group and the other 35 were in the control group, taken by using a consecutive sampling technique. The data were gathered using the Diabetes Self-Management Questionnaires (DSMQ) and the Summary of Diabetes Self-Care Activities (SDSCA) questionnaires. The gathered data were analyzed by using paired t-test, and independent t-test. The results of the study showed that there were significantly differences of mean scores of self management and self care behaviors between intervention and control groups </em>(<em>t</em>=13.24; <em>p</em>=0.00) and<em>(t=14.63,</em><em></em><em>p=0.00), respectively. It is recommended that cognitive behavior therapy can be used as one of the non-pharmacological therapies</em><em></em><em>to change self-care behaviors in type 2 DM patients.</em></p>

scholarly journals Genome-wide DNA methylation profiling of human diabetic peripheral neuropathy in subjects with type 2 diabetes mellitus

Epigenetics ◽  
2019 ◽  
Vol 14 (8) ◽  
pp. 766-779 ◽  
Author(s):  
Kai Guo ◽  
Sarah Elzinga ◽  
Stephanie Eid ◽  
Claudia Figueroa-Romero ◽  
Lucy M. Hinder ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Dna Methylation ◽  
Type 2 Diabetes Mellitus ◽  
Peripheral Neuropathy ◽  
Diabetic Peripheral Neuropathy ◽  
Genome Wide ◽  
Dna Methylation Profiling ◽  
Methylation Profiling

The effects of a supportive-educational intervention on women with type 2 diabetes and diabetic peripheral neuropathy: a randomized controlled trial

2020 ◽  
Vol 34 (6) ◽  
pp. 794-802
Author(s):  
Zohre Ahrary ◽  
Shahla Khosravan ◽  
Ali Alami ◽  
Mahdi Najafi Nesheli
Keyword(s):  
Type 2 Diabetes ◽  
Peripheral Neuropathy ◽  
Educational Intervention ◽  
Diabetic Peripheral Neuropathy ◽  
Glycosylated Hemoglobin ◽  
Self Care ◽  
Control Group ◽  
Trial Group ◽  
Diabetes Clinic

Purpose: To determine the effect of a supportive educational intervention based on the Orem self-care model on women with type 2 diabetes and diabetic peripheral neuropathy. Design: A randomized controlled trial. Setting: Hospital outpatient diabetes clinic. Subjects: Adult women with type 2 diabetes and mild-to-moderate diabetic peripheral neuropathy. Out of 410 patients, 120 diabetic patients were recruited and randomly assigned to trial group ( N = 60) and control group ( N = 60). Intervention: The trial group received a designed intervention consist of one-month supportive educational program with three months of follow-up (totally four months), based on self-care requisites according to the Orem self-care regarding diabetic peripheral neuropathy. The control group only received a routine care program in the diabetes clinic. Main measurements: The main outcomes were symptoms and severity of diabetic neuropathy. Further outcomes were fasting blood sugar and glycosylated hemoglobin. Results: By the end of the intervention, the number of participants reduced from 60 to 58 in the trial group and to 57 in the control group (totally 115). The intervention significantly decreased mean score of diabetic neuropathy symptoms (trial group: 3.26 vs. control group: 9.57, P = 0.001), severity (trial group: 5.86 vs. control group: 9.02, P = 0.001), fasting blood sugar (trial group: 151 vs. control group: 204, P = 0.001), and glycosylated hemoglobin (trial group: 7.85 vs. control group: 8.62, P = 0.004). Conclusion: Delivering a supportive-educational intervention based on the Orem self-care model on outpatient diabetes clinic can decrease the symptoms and severity of diabetic peripheral neuropathy. Trial registration: It was registered in the Iranian Registry of Clinical Trials (IRCT2015021521095N1).

Diabetic peripheral neuropathy is highly associated with nontraumatic fractures in Korean patients with type 2 diabetes mellitus

2012 ◽  
Vol 77 (1) ◽  
pp. 51-55 ◽  
Author(s):  
Ji-Hyun Kim ◽  
Mi-Hyang Jung ◽  
Jung-Min Lee ◽  
Hyun-Shik Son ◽  
Bong-Yun Cha ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Peripheral Neuropathy ◽  
Diabetic Peripheral Neuropathy ◽  
Korean Patients
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