scholarly journals A PROSPECTIVE OBSERVATIONAL STUDY ON EVALUATION OF COMPLICATIONS IN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME

2020 ◽  
Vol 11 (7) ◽  
pp. 10-12
Author(s):  
M Vidhya ◽  
Ch Bindhu ◽  
G Mounika ◽  
K Harika
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Polycystic Ovarian Syndrome ◽  
Ovarian Syndrome

scholarly journals Prevalence and pattern of PCOS in women presenting with acne, a hospital based prospective observational study

2018 ◽  
Vol 6 (3) ◽  
pp. 899
Author(s):  
Raja Shareef A. ◽  
P. V. S. Prasad ◽  
P. K. Kaviarasan
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Polycystic Ovarian Syndrome ◽  
Acne Vulgaris ◽  
Strong Association ◽  
Tertiary Care ◽  
Final Analysis ◽  
Endocrine Disorders ◽  
Medical College ◽  
Ovarian Syndrome

Background: Acne is one of the most common dermatological conditions encountered in day to day practice. Many recent studies have reported a strong association between acne and underlying systemic endocrine disorders, more particularly Poly cystic ovarian syndrome. But there is scarcity of literature on the subjects in Indian population. Hence the present study was conducted with an objective of studying the association between acne and polycystic ovarian syndrome, in women presenting with adult onset acne to a tertiary care teaching hospital.Methods: A prospective observational study was carried out in department of dermatology, Dhananalakshmi Srinivasan medical college and hospital, Permabalur from January 2016 to August 2017. The study population included women above 18 years of age clinically diagnosed with acne vulgaris. The presence of polycystic ovarian syndrome was assessed using Rotterdam criteria.Results: The final analysis had included 100 women with acne. The most common type of lesion observed was comedone in 91% of women. The other most common lesions were papule seen in 73%, pustule in 35% of women. The proportion with grade I, Grade II and grade III acne was 58%, 29% and 13% respectively. The prevalence of PCOS was 30% (95% CI 21.89% to 39.58%). PCOS had shown no statistically significant association with age, marital status and regularity of menstrual cycle. The factors which have shown statistically significant association were higher BMI, presence of Hirsutism and higher waist circumference.Conclusions: PCOS is highly prevalent among women with acne. Presence of hirsutism, obesity are strong risk factors for PCOS.

scholarly journals Effect of metformin in treating polycystic ovarian syndrome among women attending a tertiary care setting -A prospective observational study

2021 ◽  
Vol 8 (2) ◽  
pp. 188-193
Author(s):  
Suresh Chandra Mondal ◽  
Pinaki Sarkar
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Polycystic Ovarian Syndrome ◽  
Care Setting ◽  
Statistical Significance ◽  
Tertiary Care ◽  
Reproductive Age ◽  
Significant Difference ◽  
Tertiary Care Setting ◽  
Ovarian Syndrome

To determine the efficacy of metformin on clinical profile and metabolic disorders in women with polycystic ovarian syndrome. Polycystic ovarian syndrome, is a heterogeneous endocrinological disorder affecting women of reproductive age and metformin was introduced to influence the pathogenesis.: A prospective observational study was conducted on 100 women with polycystic ovarian syndrome, attending department of gynaecology in a tertiary care setting and were divided into two group of 50 each. Metformin was used in 50 patients for one year. Rest 50 patients were advised about diet control and exercise. The parameters like body mass index (BMI), weight, hormonal imbalance, ovulation, and menstrual changes were analysed in both groups. Descriptive statistics for mean, SD were carried and chi-square test was used to test statistical significance using coGuide version V.1.0 and p value set at < 0.05.: The mean age was 25±10 years. Both the groups were comparable with respect to BMI and weight. There was a significant difference between the groups with respect to fasting insulin, which reduced to 7.44±1.12 from 11.97±2mIU/ml, testosterone levels reduced to 0.59±0.1 from 0.76±0.3 mIU/ml, luteinizing hormone levels reduced to 8.55±2 from 20.01±7.3 mIU/ml, and LH:FSH ratio reduced to 1.11±0.1 from 2.31±0.2 mIU/ml. In the metformin group, 22 (44%) participants were anovulation before treatment, and ovulation started in 15 (30%) after treatment which was not seen other group.Clinical, hormonal, and biochemical changes in polycystic ovarian syndrome may effectively be treated by metformin.

scholarly journals Effect of Myoinositol and Metformin in combination on clinical and hormonal profile in patients of polycystic ovarian syndrome

2019 ◽  
Vol 8 (2) ◽  
pp. 702
Author(s):  
Tripti Nagaria ◽  
Arpita Mohapatra ◽  
Jyoti Jaiswal
Keyword(s):  
Prospective Observational Study ◽  
Polycystic Ovarian Syndrome ◽  
Drug Dosage ◽  
Clinical Profile ◽  
Cutaneous Manifestations ◽  
Medical College ◽  
Maximum Improvement ◽  
Androgenic Hormone ◽  
Ovarian Syndrome ◽  
Spontaneous Onset

Background: Polycystic ovarian syndrome (PCOS) also known as hyperandrogenic anovulation syndrome or Stein – Leventhal syndrome is an endocrine disorder, characterized by anovulation, oligomenorrhea, amenorrhea, features of androgenic hormone excess (hirsutism, acne, alopecia, seborrhea) and insulin resistance. The global prevalence ranges from 2.2% to 26%. Methods: A prospective observational study was conducted from December 2015 to December 2016 in Department of Obstetrics and Gynecology at Pt. Jawahar Lal Nehru Memorial medical college and associated Dr. Bhim Rao Ambedkar memorial hospital, Raipur (C.G.) after obtaining permission of ethical committee of the institute to evaluate the effect of myoinositol and metformin on clinical profile in patients of polycystic ovarian syndrome. 70 women were included in the study who received a combination of myoinositol 600mg and metformin 500mg (twice a day) for 3 months for the management of PCOS. Prior to the start of the therapy, a detailed history and baseline investigations were recorded. Cases were reassessed at the end of three months of therapy for evaluation of change in clinical and hormonal profile.Results: 90.09% (63/70) cases showed improvement in the menstrual complaints. Spontaneous onset of menses occurred in all the cases presented with amenorrhea, in nearly 90% within 2 months of start of treatment. Regularization of cycles was observed in nearly 50% of patients with infrequent menses. Amongst all the cases with cutaneous manifestations, maximum improvement was seen in cases of acne (4/6) i.e. 66.66%. 25% (5/20) patients with infertility conceived during the study period.Conclusions: Myoinositol with metformin in combination has resulted in significant improvement in the clinical profile with reduction in individual drug dosage in cases with PCOS.

scholarly journals Association of metabolic syndrome in polycystic ovarian syndrome: an observational study

2011 ◽  
Vol 61 (2) ◽  
pp. 176-181 ◽  
Author(s):  
Ramprasad Dey ◽  
Shiuli Mukherjee ◽  
Ranu Roybiswas ◽  
Arunima Mukhopadhyay ◽  
S. C. Biswas
Keyword(s):  
Metabolic Syndrome ◽  
Observational Study ◽  
Polycystic Ovarian Syndrome ◽  
Ovarian Syndrome
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