scholarly journals FUNCTIONAL AND PHARMACOLOGICAL PROPERTIES OF BHRINGARAJA: A REVIEW

2021 ◽  
Vol 12 (5) ◽  
pp. 63-66
Author(s):  
Sneha S Air ◽  
Pravin M Bhat
Keyword(s):  
Chemical Compounds ◽  
Eye Diseases ◽  
The Body ◽  
Eye Disease ◽  
Evidence Based ◽  
Systemic Diseases ◽  
Body Parts ◽  
Eclipta Alba ◽  
Based Medicine ◽  
Asteraceae Family

Bhringaraja (Eclipta alba) of the Asteraceae family is used in various Kalpa to treat eye disease because of its Chakshushya properties. It is also used in naktyandhtva and widely used in liver disease, anemia, eye disease, problem-related to hairs. It is having antibacterial, analgesic, antifungal, antiviral, antihepatotoxic, immunomodulatory, neuroprotective properties. It contains chemical compounds including coumarins, alkaloids, flavonoids etc. Because of these properties, it is used in various eye diseases. The eye is also made from the Panchamahabhutas like other body parts. Every part of the body is developed from a neural tube i.e., ectoderm and mesoderm like this every part or layer of the eyeball develop from the optic vesicle, the ectoderm and mesoderm, as the origin is the same. Also, many eye-related symptoms are seen in various systemic diseases. Eclipta alba can be used in various diseases which has ocular manifestation with different concentrations and in various formulation with appropriate concentration along with other herbs. So, we need to develop appropriate formulation for evidence-based medicine.

scholarly journals Evolving paradigms in the field of periodontal medicine: A review

2021 ◽  
Vol 6 (3) ◽  
pp. 136-142
Author(s):  
Vindeshwari Bhatia ◽  
Ajay Mahajan ◽  
Kanwarijit Singh Asi ◽  
Ashadeep
Keyword(s):  
Evidence Base ◽  
Evidence Based ◽  
Systemic Diseases ◽  
Periodontal Health ◽  
Focal Infection ◽  
Systemic Health ◽  
Based Medicine ◽  
The Impact ◽  
Periodontal Medicine ◽  
Underlying Pathophysiology

The association between the oral and systemic health has been a matter of discussion since the focal infection theory of the early 20century. This field has evolved with supportable evidence linking poor periodontal status with systemic diseases and extensive research on this complex relationship has given rise to new field of “Periodontal Medicine.” Although the evidence base is quite large on the impact of systemic disorders on periodontium but a smaller but growing evidence base supports an association between poor periodontal health and systemic diseases. Moreover, today’s era of evidence-based medicine and dentistry provides an excellent environment to examine the possible relationships between oral infection and systemic disorders. Therefore, the purpose of writing this review article is to understand the underlying pathophysiology between periodontal health and systemic health with particular focus on the effects of periodontal disease on systemic outcomes.

scholarly journals A review on traditional uses, phytochemistry and pharmacological properties of Eclipta alba (Linn.) Hassk - an innumerable medicinal plant.

2020 ◽  
Author(s):  
Md Liton Rana
Keyword(s):  
Medicinal Plant ◽  
Folk Medicine ◽  
Chemical Compounds ◽  
Chemical Components ◽  
Subtropical Region ◽  
Pharmacological Activities ◽  
Eclipta Alba ◽  
Vernacular Names ◽  
Almost All ◽  
Asteraceae Family

Eclipta alba is a common folk medicinal plant which is generously known as bhringraj in Indian traditional medicine and as false daisy in English. It belongs to the Asteraceae family, found in almost all over the globe specially in tropical and subtropical region with various vernacular names include kesuriya (Bengali), maakaa (Marathi), yerba de tago (Minnesota), Kehraj (Assamese), Karisalankanni (Tamil), galagara (Telugu), bhangaro (Guajarati), bhangaara (Hindi). The plant has been traditionally used in folk medicine along with Ayurveda and Siddha for its curative properties where it is utilized as anticancer, antimicrobial, analgesic, anti-venom, antioxidant, antimytotoxic, antihyperglycemic, immunomodulatory properties. A broad range of chemical components including alkaloids, coumentans, flavonoids, polyacetylenes, triterpenes, thiopenes and their derivatives have been extracted from this species. These phytochemicals show different pharmacological activities against several common diseases. This contribution provides update about isolated and identified chemical compounds from the plant extract and their traditional and pharmacological activities.

scholarly journals Diagnostics of mechanical asphyxia – experience of foreign countries (literature review)

2021 ◽  
pp. 45-49
Author(s):  
Iryna Yakovtsova ◽  
Olexandr Hurov ◽  
Vadym Nikonov ◽  
Sergii Kursov ◽  
Dmytro Hladkykh ◽  
...  
Keyword(s):  
Research Methods ◽  
Evidence Based Medicine ◽  
Alcohol Intoxication ◽  
Morphological Features ◽  
The Body ◽  
Immunohistochemical Method ◽  
Evidence Based ◽  
Morphological Studies ◽  
Based Medicine ◽  
Mechanical Asphyxia

The aim of this study is to establish modern, global trends in the diagnosis of mechanical asphyxia. Materials and methods: search and bibliographic method (theoretical analysis, systematization and classification of library catalogues, printed and electronic sources on mechanical asphyxia) from open anchor databases Scopus preview, Web of Science and using information retrieval systems Google Scholar, Open Ukrainian Citation Index (OUCI), ScienceDirect on the Internet. Results: mechanical asphyxia, as one of the most common types of violent death, ranks first among deaths from mechanical injuries. Its study is of great interest among medical scientists in various fields, especially for resuscitators and forensic experts. Establishing the causes of asphyxia, clinical and morphological manifestations, and the consequences that unfortunately most often lead to death. With the rapid development of society, science is also developing rapidly, and the latest sensitive methods of diagnosing diseases are emerging. However, unfortunately, in the post-Soviet space, the diagnosis of most pathological conditions, including asphyxia, is determined by experience and sensory organs, which are determined using instrumental research methods in compliance with the requirements of evidence-based medicine. Given the peculiarities of the pathophysiological processes of the asphyxiation state and their manifestations in the body, doctors should rely primarily on general knowledge about hypoxic and asphyxiation disorders, which are determined using instrumental research methods in compliance with the requirements of evidence-based medicine. Conclusions: at present, the diagnosis of asphyxia consists of many morphological features. Failure to take into account the state of the body, the presence of chronic diseases, and drug or alcohol intoxication at the time of asphyxiation complicate the diagnosis. Detection of individual clinical manifestations or morphological features does not allow asserting its lifelong origin. Therefore, it is necessary to use modern research methods that should expand the possibilities of forensic diagnosis of the viability of injuries in terms of evidence-based medicine and provide forensic experts with a scientific basis for their results. One such method is immunohistochemical, which is gaining popularity and consolidating its position in the EU, China, Japan and America. In addition, this method is well-established and widespread in morphological studies of differential diagnosis of tumours. Some scientific works prove the expediency of using the immunohistochemical method to solve the problems of forensic expert practice, which is an actual scientific and practical task

Cholangiokarzinome

Praxis ◽  
2002 ◽  
Vol 91 (34) ◽  
pp. 1352-1356
Author(s):  
Harder ◽  
Blum
Keyword(s):  
Supportive Care ◽  
Evidence Based Medicine ◽  
Best Supportive Care ◽  
Evidence Based ◽  
Systemische Chemotherapie ◽  
Chirurgische Resektion ◽  
Multimodale Therapiekonzepte ◽  
Based Medicine

Cholangiokarzinome oder cholangiozelluläre Karzinome (CCC) sind seltene Tumoren des biliären Systems mit einer Inzidenz von 2–4/100000 pro Jahr. Zu ihnen zählen die perihilären Gallengangskarzinome (Klatskin-Tumore), mit ca. 60% das häufigste CCC, die peripheren (intrahepatischen) Cholangiokarzinome, das Gallenblasenkarzinom, die Karzinome der extrahepatischen Gallengänge und das periampulläre Karzinom. Zum Zeitpunkt der Diagnose ist nur bei etwa 20% eine chirurgische Resektion als einzige kurative Therapieoption möglich. Die Lebertransplantation ist wegen der hohen Rezidivrate derzeit nicht indiziert. Die Prognose von nicht resektablen Cholangiokarzinomen ist mit einer mittleren Überlebenszeit von sechs bis acht Monaten schlecht. Eine wirksame Therapie zur Verlängerung der Überlebenszeit existiert aktuell nicht. Die wichtigste Massnahme im Rahmen der «best supportive care» ist die Beseitigung der Cholestase (endoskopisch, perkutan oder chirurgisch), um einer Cholangitis oder Cholangiosepsis vorzubeugen. Durch eine systemische Chemotherapie lassen sich Ansprechraten von ca. 20% erreichen. 5-FU und Gemcitabine sind die derzeit am häufigsten eingesetzten Substanzen, die mit einer perkutanen oder endoluminalen Bestrahlung kombiniert werden können. Multimodale Therapiekonzepte können im Einzellfall erfolgreich sein, müssen jedoch erst in Evidence-Based-Medicine-gerechten Studien evaluiert werden, bevor Therapieempfehlungen für die Praxis formuliert werden können.

The Commitment of the Documentation Service of the Swiss Academy of Medical Sciences for the Impartment of Evidence Based Medicine

Swiss Surgery ◽  
1999 ◽  
Vol 5 (4) ◽  
pp. 183-185
Author(s):  
Bleuer
Keyword(s):  
Evidence Based Medicine ◽  
Cochrane Library ◽  
Evidence Based ◽  
Medical Sciences ◽  
Based Medicine

Die mit dem Aufkommen der elektronischen Medien einhergehende Informationsflut hat die Erwartungen an den Dokumentationsdienst (DOKDI) der Schweizerischen Akademie der Medizinischen Wissenschaften verändert: Insbesondere Evidence Based Medicine (EBM) verlangt nicht nur die Beschaffung von Information, sondern auch eine Selektion hinsichtlich Qualität und Relevanz: Die sich aus der klinischen Situation ergebende Frage fordert eine Antwort, die inhaltlich richtig ist und in der konkreten Situation auch weiterhilft. Dem Ideal, sich durch kritische Lektüre der Originalarbeiten ein Bild über die vorhandene Evidenz für die Richtigkeit eines bestimmten Prozederes zu verschaffen, stehen in der Praxis meist Zeitmangel und methodische Schwierigkeiten im Weg; man wird sich deshalb oft auf die durch andere erarbeitete Evidenz abstützen müssen und z.B. die Cochrane Library konsultieren. Der DOKDI engagiert sich sowohl bei der Erarbeitung von systematischen Übersichtsarbeiten als auch bei der Dissemination der gefundenen Evidenz, indem er seine Erfahrung in der Dokumentation mit elektronischen Medien und die entsprechende Infrastruktur zur Verfügung stellt. Als Ergänzung zu diesen Aktivitäten hat die Akademie einen Grant zur Ausbildung von EBM-Tutoren gesprochen. In einem einwöchigen Kurs in Oxford werden Kliniker zu EBM-Tutoren ausgebildet: Dies wird zukünftig ermöglichen, vermehrt EBM-Workshops in der Schweiz durchzuführen.

Stellenwert der Kinderneurologie im interdisziplinären Ansatz der Frühförderung

2003 ◽  
Vol 12 (1) ◽  
pp. 3-11 ◽  
Author(s):  
Ingrid Müller
Keyword(s):  
Evidence Based Medicine ◽  
Evidence Based ◽  
Based Medicine ◽  
Kosten Im Gesundheitswesen

Zusammenfassung. Die kinderneurologische Begleitung erfüllt zwei wesentliche Aufgaben innerhalb des interdisziplinären Konzepts der Frühförderung. Sie ist zum einen Teil des Diagnostik- und Therapieprozesses; dieser orientiert sich an der neurophysiologischen Erkenntnis, dass das Gehirn ein sich selbst organisierendes System ist und seine Funktionalität in der Interaktion mit dem Umfeld entwickelt. Heutige kinderneurologische Diagnostik basiert daher auf einem systemisch-ökologischen Ansatz. Zum anderen tragen entwicklungsneurologische Befunde, die sich zur prognostischen Beurteilung therapeutischer Maßnahmen eignen, wesentlich zur Qualitätssicherung und -kontrolle in der Frühförderung bei. In den letzten Jahren ist eine Inflation bei der Verordnung entwicklungsfördernder Maßnahmen zu beobachten. Um eine Explosion der Kosten im Gesundheitswesen zu verhindern, werden sich in Zukunft Kriterien der evidence-based medicine auch in der Frühförderung durchsetzen müssen.

The Evolution of Music Therapy

2015 ◽  
Vol 26 (4) ◽  
pp. 207-221
Author(s):  
Wolfgang Mastnak
Keyword(s):  
Music Therapy ◽  
Evidence Based Medicine ◽  
Wide Spectrum ◽  
Evidence Based ◽  
Modern Music ◽  
Guided Imagery And Music ◽  
Theoretical Perspectives ◽  
International Importance ◽  
Evolution Of Music ◽  
Based Medicine

Abstract. Five overlapping eras or stages can be distinguished in the evolution of music therapy. The first one refers to the historical roots and ethnological sources that have influenced modern meta-theoretical perspectives and practices. The next stage marks the heterogeneous origins of modern music therapy in the 20th century that mirror psychological positions and novel clinical ideas about the healing power of music. The subsequent heyday of music therapeutic models and schools of thought yielded an enormous variety of concepts and methods such as Nordoff–Robbins music therapy, Orff music therapy, analytic music therapy, regulatory music therapy, guided imagery and music, sound work, etc. As music therapy gained in international importance, clinical applications required research on its therapeutic efficacy. According to standards of evidence-based medicine and with regard to clearly defined diagnoses, research on music therapeutic practice was the core of the fourth stage of evolution. The current stage is characterized by the emerging epistemological dissatisfaction with the paradigmatic reductionism of evidence-based medicine and by the strong will to discover the true healing nature of music. This trend has given birth to a wide spectrum of interdisciplinary hermeneutics for novel foundations of music therapy. Epigenetics, neuroplasticity, regulatory and chronobiological sciences, quantum physical philosophies, universal harmonies, spiritual and religious views, and the cultural anthropological phenomenon of esthetics and creativity have become guiding principles. This article should not be regarded as a historical treatise but rather as an attempt to identify theoretical landmarks in the evolution of modern music therapy and to elucidate the evolution of its spirit.

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