Evolving paradigms in the field of periodontal medicine: A review

The association between the oral and systemic health has been a matter of discussion since the focal infection theory of the early 20century. This field has evolved with supportable evidence linking poor periodontal status with systemic diseases and extensive research on this complex relationship has given rise to new field of “Periodontal Medicine.” Although the evidence base is quite large on the impact of systemic disorders on periodontium but a smaller but growing evidence base supports an association between poor periodontal health and systemic diseases. Moreover, today’s era of evidence-based medicine and dentistry provides an excellent environment to examine the possible relationships between oral infection and systemic disorders. Therefore, the purpose of writing this review article is to understand the underlying pathophysiology between periodontal health and systemic health with particular focus on the effects of periodontal disease on systemic outcomes.

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Clinical epidemiology in complementary medicine (discussion)

Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) ◽

10.33920/med-01-2106-06 ◽

2021 ◽

pp. 465-474

Author(s):

Yuriy Olegovich Novikov ◽

Mikhail Borisovich Tsykunov ◽

Ayrat Rafikovich Shayakhmetov

Keyword(s):

Complementary Medicine ◽

Clinical Epidemiology ◽

Response To Treatment ◽

Evidence Based ◽

New Paradigm ◽

Treatment And Prevention ◽

Healthcare It ◽

Analytical Review ◽

Based Medicine ◽

The Impact

The article presents an analytical review of the literature on the application of the principles of evidence-based medicine in modern healthcare. It is noted that in some areas of medicine, scientifically based standards of treatment significantly fall behind the general trends. Complementary medicine, including osteopathy, is an important healthcare resource, the use of which is officially recognized in 94 countries around the world. However, despite certain achievements in the treatment and prevention of many chronic diseases, there are scientific articles that criticize its effectiveness. Therefore, the relevance of obtaining new, strictly evidence-based data on the impact of osteopathy on health is beyond doubt. For osteopathy, as for other types of complementary medicine, a new paradigm of evidence-based clinical research is probably needed. Three types of the organism response to treatment — instant, fast and delayed — are identified.

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What Can Feminist Epistemology Do for Surgery?

Hypatia ◽

10.1111/hypa.12052 ◽

2014 ◽

Vol 29 (2) ◽

pp. 404-421 ◽

Cited By ~ 1

Author(s):

Mary Jean Walker ◽

Wendy Rogers

Keyword(s):

Health Care ◽

Evidence Base ◽

Feminist Epistemology ◽

Cultural Barriers ◽

Evidence Based ◽

Surgical Practice ◽

Lack Of Fit ◽

What Works ◽

Based Medicine ◽

Contemporary Health Care

Surgery is an important part of contemporary health care, but currently much of surgery lacks a strong evidence base. Uptake of evidence‐based medicine (EBM) methods within surgical research and among practitioners has been slow compared with other areas of medicine. Although this is often viewed as arising from practical and cultural barriers, it also reflects a lack of epistemic fit between EBM research methods and surgical practice. In this paper we discuss some epistemic challenges in surgery relating to this lack of fit, and investigate how resources from feminist epistemology can help to characterize them. We point to ways in which these epistemic challenges may be addressed by gathering and disseminating evidence about what works in surgery using methods that are contextual, pluralistic, and sensitive to hierarchies.

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Microfracture: State of the Art in Cartilage Surgery?

Cartilage ◽

10.1177/1947603517700956 ◽

2017 ◽

Vol 9 (4) ◽

pp. 339-345 ◽

Cited By ~ 5

Author(s):

Florian Frehner ◽

Jan P. Benthien

Keyword(s):

Clinical Trials ◽

Impact Factor ◽

Sports Medicine ◽

Time Frame ◽

Evidence Based ◽

Yearly Average ◽

The Mean ◽

Based Medicine ◽

Number Of Citations ◽

The Impact

Objective This study is a literature review from 2010 to 2014 concerning the quality of evidence in clinical trials about microfracture in attempt to repair articular cartilage. We have decided to focus on microfracturing, since this seems to be the best documented technique. Interest in evaluation of publication quality has risen in orthopaedic sports medicine recently. Therefore, we think it is necessary to evaluate recent clinical trials being rated for their evidence-based medicine (EBM) quality. We also compared the mean impact factor of the journals publishing the different studies as an indicator of the study’s citation and evaluated for a change over the studied time frame. Design To measure the EBM level, we applied the modified Coleman Methodology Score (CMS) introduced by Jakobsen. The impact factor, which is a measurement of the yearly average number of citations of articles recently published in that journal, was evaluated according to self-reported values on the corresponding journal’s website. Results We found that the mean CMS has not changed between 2010 and 2014. The mean impact factor has also not changed between 2010 and 2014. The CMS variance was high, pointing to different qualities in the evaluated studies. There is no evidence that microfracturing is superior compared to other cartilage repair procedures. Conclusion Microfracture cannot be seen as an evidence based procedure. Further research needs to be done and a standardization of the operating method is desirable. There need to be more substantial studies on microfracturing alone without additional therapies.

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Evidence-Based Global Public Health

When People Come First ◽

10.23943/princeton/9780691157382.003.0004 ◽

2013 ◽

Cited By ~ 5

Author(s):

Vincanne Adams

Keyword(s):

Public Health ◽

Health Care ◽

Global Health ◽

Experimental Research ◽

Evidence Based ◽

Global Public Health ◽

The Social ◽

Research Populations ◽

Based Medicine ◽

The Impact

This chapter examines the impact of “evidence-based medicine” (EBM) on global public health. An epistemic transformation in the field of global health is underway, and it argues that the impact of EBM has been twofold: (1) the creation of an experimental metric as a means of providing health care; and (2) a shift in the priorities of caregiving practices in public health such that “people [no longer] come first.” The production of experimental research populations in and through EBM helps constitute larger fiscal transformations in how we do global health. Notably, EBM has created a platform for the buying and selling of truth and reliability, abstracting clinical caregiving from the social relationships on which they depend.

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Unhealthy Politics

10.23943/princeton/9780691203225.001.0001 ◽

2020 ◽

Author(s):

Eric M. Patashnik ◽

Alan S. Gerber ◽

Conor M. Dowling

Keyword(s):

United States ◽

Health Care ◽

Scientific Evidence ◽

The United States ◽

Evidence Base ◽

Medical Industry ◽

Evidence Based ◽

Evidence Based Practices ◽

Delivery Of Medical Care ◽

Based Medicine

The U.S. medical system is touted as the most advanced in the world, yet many common treatments are not based on sound science. This book sheds new light on why the government's response to this troubling situation has been so inadequate, and why efforts to improve the evidence base of U.S. medicine continue to cause so much political controversy. The book paints a portrait of a medical industry with vast influence over which procedures and treatments get adopted, and a public burdened by the rising costs of health care yet fearful of going against “doctor's orders.” It offers vital insights into the limits of science, expertise, and professionalism in American politics. The book explains why evidence-based medicine is important. First, the delivery of unproven care can expose patients to serious risks. Second, the slow integration of evidence can lead to suboptimal outcomes for patients who receive treatments that work less well for their conditions than alternatives. Third, the failure to implement evidence-based practices encourages wasteful spending, causing the health care system to underperform relative to its level of investment. This book assesses whether the delivery of medical care in the United States is evidence based. It argues that by systematically ignoring scientific evidence (or the lack thereof), the United States is substantially out of balance.

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25. WHAT'S THE EVIDENCE? EVALUATING THE IMPACT OF A RESIDENT EVIDENCE-BASED MEDICINE CURRICULUM

Academic Pediatrics ◽

10.1016/j.acap.2020.06.046 ◽

2020 ◽

Vol 20 (7) ◽

pp. e13-e14

Author(s):

Minnie Dasgupta ◽

Danielle Kirkey ◽

Jake Weatherly ◽

Kevin Kuo ◽

Carrie Rassbach

Keyword(s):

Evidence Based Medicine ◽

Evidence Based ◽

Based Medicine ◽

The Impact

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Assessment of the Impact of Clinical Pharmacology Consultations Provided to Hospital Clinicians From the Drug Information Center—An Outcome Research in a Developing Country

Journal of Pharmacy Practice ◽

10.1177/0897190019885256 ◽

2019 ◽

pp. 089719001988525

Author(s):

CVN Harish ◽

Devaraj Belavigi ◽

Amol N. Patil ◽

Smita Pattanaik ◽

Ashish Kakkar ◽

...

Keyword(s):

Health Care ◽

Evidence Based Medicine ◽

Drug Information ◽

Care Practice ◽

Fisher Exact Test ◽

Evidence Based ◽

Care Hospital ◽

Information Center ◽

Based Medicine ◽

The Impact

Background: Drug Information Center (DIC) with on-call evidence-based medicine service can revolutionize health-care practice and also can play a major role in health-care delivery in both developed and developing countries. Objective: To assess the feedback received from hospital clinicians for the newly initiated DIC services in a tertiary care hospital of North India. Methods: This is a retrospective cohort study conducted between January 1, 2016, to December 31, 2018. The clinicians approached DIC for specific pharmacotherapeutic questions for managing an index patient. After providing consultation, DIC followed up with them for the action taken and feedback on the consultation. The results of the data analyzed using Fisher Exact test and descriptive statistics. Results: Of 264 encounters, more than 98% of clinicians found the service satisfactory. There was a statistically significant association between the timely answer provided to treating physicians and their level of satisfaction with the service ( P < .05). There was no significant association between academic experiences and the satisfaction or dissatisfaction among the clinical fraternity colleagues. The interpretation ability of on-call pharmacology postgraduate students was a significantly associated factor with clinician’s satisfaction level ( P < .05). More than 96% of clinicians followed the pharmacotherapy advice recommended by DIC in their patient management. Conclusion: Thorough evaluation of published research needs to be taught to budding pharmacologists, pharmacists in their curriculum for an effective DIC service. DIC service has the potential to minimize the barrier of evidence-based medicine practice in developing as well as developed countries.

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PNS334 SCIENTIFIC MISCONDUCT AND SYSTEMATIC LITERATURE REVIEWS (SLRS): THE IMPACT OF FRAUDULENT CLINICAL STUDIES ON EVIDENCE-BASED MEDICINE

Value in Health ◽

10.1016/j.jval.2019.09.2234 ◽

2019 ◽

Vol 22 ◽

pp. S820

Author(s):

J.C. Thompson ◽

D.A. Scott

Keyword(s):

Evidence Based Medicine ◽

Clinical Studies ◽

Scientific Misconduct ◽

Evidence Based ◽

Literature Reviews ◽

Based Medicine ◽

The Impact

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The Cat with Neurological Manifestations of Systemic Disease

Journal of Feline Medicine and Surgery ◽

10.1016/j.jfms.2009.03.007 ◽

2009 ◽

Vol 11 (5) ◽

pp. 395-407 ◽

Cited By ~ 12

Author(s):

Marc Kent

Keyword(s):

Nervous System ◽

Early Recognition ◽

Systemic Disease ◽

Clinical Signs ◽

Evidence Base ◽

Neurological Deficits ◽

Systemic Diseases ◽

Special Issue ◽

The Impact ◽

Prompt Diagnosis

Practical relevance A number of systemic diseases are associated with neurological deficits. Most systemic diseases that impact on the nervous system result in multifocal neurological signs; however, isolated deficits can also be observed. This article reviews the clinical signs, pathophysiology, diagnosis, treatment and prognosis of four important systemic diseases with neurological consequences: feline infectious peritonitis, toxoplasmosis, hypertension and hepatic encephalopathy. Clinical challenges Early recognition of systemic signs of illness in conjunction with neurological deficits will allow for prompt diagnosis and treatment. While neurological examination of the feline patient can undoubtedly be challenging, hopefully the accompanying articles in this special issue will enable the clinician to approach these cases with more confidence. Evidence base The veterinary literature contains numerous reports detailing the impact of systemic disease on the nervous system. Unfortunately, very few references provide detailed descriptions of large cohorts of affected cats. This review summarises the literature underpinning the four key diseases under discussion.

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