scholarly journals Association of Epicardial Adipose Tissue Thickness with Left Atrial Size and Atrial Fibrillation

2021 ◽  
pp. 60-66
Author(s):  
Ahmed M. Abd ElSalam ◽  
Amany M. Allaithy ◽  
Mona Elsaedy ◽  
Ekram Sadek Said
Keyword(s):  
Atrial Fibrillation ◽  
Adipose Tissue ◽  
Left Atrial ◽  
Epicardial Adipose Tissue ◽  
Left Atrial Size ◽  
Operating Characteristics ◽  
Tissue Thickness ◽  
Epicardial Adipose Tissue Thickness ◽  
Atrial Size ◽  
Significant Difference

Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with detrimental consequences. Epicardial fat is consistently associated with the presence, severity, and recurrence of AF. Aim: The aim of the work was to investigate the association of epicardial adipose tissue thickness with left atrial size in patients with atrial fibrillation. Patients and Methods: This study was conducted on 25 atrial fibrillation (AF) patients and 25 subjects with normal sinus rhythm as a control group matched in body weight. All patients underwent transthoracic echocardiogram. EAT (epicardial adipose tissue) thickness was measured on the right ventricular free wall of the two- dimensional parasternal long-axis view at end systole.  Results: The results showed that there was a significant difference between the two groups in waist circumference, EAT (epicardial adipose tissue) thickness, left atrium diameter, LA volume. Receiver operating characteristics (ROC) analysis showed that an EAT thickness of > 0.30 cm maximizes the sensitivity and specificity to predict the development of AF. Conclusion: Increases epicardial adipose tissue is associated with the occurrence of atrial fibrillation.

scholarly journals Opposite relations of epicardial adipose tissue to left atrial size in paroxysmal and permanent atrial fibrillation

2018 ◽  
Vol 6 ◽  
pp. 205031211879990 ◽  
Author(s):  
Stavroula N Psychari ◽  
Dionysios Tsoukalas ◽  
Dimitrios Varvarousis ◽  
Anastasios Papaspyropoulos ◽  
Eleni Gkika ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Adipose Tissue ◽  
Interleukin 6 ◽  
Left Atrial ◽  
Epicardial Adipose Tissue ◽  
High Sensitivity ◽  
Left Atrial Size ◽  
Reactive Protein ◽  
Permanent Atrial Fibrillation ◽  
Atrial Size

Objectives: Atrial fibrillation has been associated with obesity in epidemiological studies. Epicardial adipose tissue is an ectopic fat depot in the proximity of atria, with endocrine and inflammatory properties that is implicated in the pathophysiology of atrial fibrillation. Inflammation also has a role in atrial arrhythmogenesis. The aim of this study was to investigate the potential relations of epicardial adipose tissue to left atrial size and to adiponectin and the pro-inflammatory mediators, high-sensitivity C-reactive protein, and interleukin-6 in paroxysmal and permanent atrial fibrillation. Methods: This was a cross-sectional study of 103 atrial fibrillation patients, divided into two subgroups of paroxysmal and permanent atrial fibrillation, and 81 controls, in sinus rhythm. Echocardiography was used for estimation of epicardial adipose tissue and left atrial size and high-sensitivity C-reactive protein, interleukin-6 and adiponectin were measured in all subjects. Results: Atrial fibrillation patients had significantly larger epicardial adipose tissue compared with controls (0.43 ± 0.17 vs 0.34 ± 0.17 cm, p = 0.002). Atrial fibrillation presence was independently related to epicardial adipose tissue thickness ( b = 0.09, p = 0.002). Opposite associations of epicardial adipose tissue with left atrial volume existed in atrial fibrillation subgroups; in the paroxysmal subgroup, epicardial adipose tissue was directly related to left atrial volume ( R = 0.3, p = 0.03), but in the permanent one the relation was inverse ( R = −0.7, p < 0.0001). Adiponectin, high-sensitivity C-reactive protein and interleukin-6 were elevated in both atrial fibrillation groups. Only interleukin-6 was related to epicardial adipose tissue size. Conclusion: Opposite associations of epicardial adipose tissue with left atrial size in paroxysmal and permanent Atrial fibrillation and elevated inflammatory markers, suggest a role of epicardial adipose tissue and inflammation in the fibrotic and remodeling process.

scholarly journals Epicardial Adipose Tissue Thickness and Ablation Outcome of Atrial Fibrillation

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e74926 ◽  
Author(s):  
Tze-Fan Chao ◽  
Chung-Lieh Hung ◽  
Hsuan-Ming Tsao ◽  
Yenn-Jiang Lin ◽  
Chun-Ho Yun ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Adipose Tissue ◽  
Epicardial Adipose Tissue ◽  
Tissue Thickness ◽  
Epicardial Adipose Tissue Thickness

P1049Influence of body mass index on recurrence in atrial fibrillation patients after radiofrequency catheter ablation

EP Europace ◽  
2020 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
S Calero Nunez ◽  
V M Hidalgo-Olivares ◽  
A De Leon-Ruiz ◽  
S Diaz-Lancha ◽  
L Exposito-Calamardo ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Body Mass Index ◽  
Catheter Ablation ◽  
Body Mass ◽  
Left Atrial ◽  
Conflicts Of Interest ◽  
Left Atrial Size ◽  
Atrial Size ◽  
Obstructive Sleep ◽  
Significant Difference

Abstract Funding Acknowledgements No conflicts of interest INTRODUCTION  Evidence has shown that obesity, expressed as high body mass index (BMI), is associated with the development of atrial fibrillation(AF). However, the relationship between BMI and recurrence of AF after catheter ablation(CA) remains controversial. Understanding this relationship, may help in regard to patient(p) counseling and management before and after CA. Purpose To evaluate single center AF recurrences after pulmonary vein isolation according to BMI status. Secondary endpoints were to compare the influence of other comorbilitys such as pulmonar disease or obstructive sleep apnea(OSA) METHODS We included 114p with AF(54,5 ± 9,6 years; male 75,4%; paroxysmal 70,2%; persistent 29,8%) treated with first time radiofrequency ablation between 2013 and 2018. On the basis of the baseline BMI, patients were categorized into 2 groups: normal/overweigth (BMI &lt; 30kg/m2) and obese(BMI≥30kg/m2). RESULTS There was no significant difference between the majority of baseline characteristics of the groups (table 1), however patients with BMI≥30 were more likely to sufferd OSA(34% vs 8,2%:p = 0,001), to have larger left atrial (diameter &gt; 40mm: 70,5% vs 46,3%;p = 0,004), and persistent AF (43,4% vs 18%; p 0,004). During 12 months of follow-up AF recurred in 34p (29,8%), the freedom from AF was significantly higher in the BMI &lt; 30 group (48p(80%) vs 31(58,5%), p = 0,015). Multivariate analysis including variables of type of AF, OSA, BMI, left atrial size, ejection fraction, and hypertension demonstrated that BMI was the strongest predictor of being freedom from recurrent AF (OR = 0.35, 95% CI: 0,11–0,81, P = 0.014). A serious complication occurred in 6p(5,3%), with no relationship to BMI. CONCLUSION This study suggest that tight association between obesity and AF recurrence after ablation may be partly due to other concomitant conditions which in turn are more frequent in obese patients like OSA, left atrial size and presence of persistent AF. Abstract Table 1

scholarly journals Epicardial Adipose Tissue Thickness, A Direct Correlation With Age And Gender In Healthy Adults And Coronary Artery Disease Patients

2018 ◽  
Vol 08 (03) ◽  
pp. 155-158
Author(s):  
Sadaf Shaheen ◽  
Sahrish Mukhtar ◽  
Iffat Raza ◽  
Bashir Sheikh
Keyword(s):  
Coronary Artery Disease ◽  
Adipose Tissue ◽  
Coronary Artery ◽  
Epicardial Adipose Tissue ◽  
Tissue Thickness ◽  
Epicardial Adipose Tissue Thickness ◽  
Significant Difference ◽  
The Mean ◽  
Artery Disease ◽  
And Gender

Objectives: The aim of this study was to measure the Epicardial Adipose Tissue thickness through echocardiography in healthy adults and coronary artery disease patients and to make its association with age and gender. Methods: It was a case control study. A total of 315 samples including 159 cases of coronary artery disease and 156 asymptomatic individuals for coronary artery disease underwent echocardiography for Epicardial Adipose Tissue thickness measurement. Results: Mean Epicardial Adipose Tissue (EAT) in the study was found to be 15.45 ± 7.16 mm. Cases had significantly higher EAT 16.77 ±9.80mm as compared to controls 14.13 ± 4.52 mm (P=0.02). EAT thickness increased significantly with age (P=0.004). There was no significant difference of EAT (P=0.999) in both the genders. Conclusion: The mean EAT thickness is significantly higher in our study population as compared to previous studies. The mean EAT thickness was same in both males and females of our study. There was no significant difference in EAT of both genders.

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