scholarly journals Assessment of Lipid Profile and Serum Creatinine Kinase in Subjects with Hyperlipidemia on Moderate Intensity Statin Therapy Attending a Postgraduate Teaching Hospital in South India

2021 ◽  
pp. 1-10
Author(s):  
T. K. Mohammed Muneersha ◽  
R. T. Saravanakumar ◽  
K. G. Revikumar
Keyword(s):  
Drug Therapy ◽  
Coronary Artery ◽  
Lipid Profile ◽  
Teaching Hospital ◽  
South India ◽  
Tertiary Care ◽  
Lifestyle Changes ◽  
Moderate Intensity ◽  
Lifestyle Modifications ◽  
Muscle Toxicity

Atherosclerosis of large and medium sized arteries are believed to be the major reason behind the development of Coronary Artery Diseases and Hyperlipidemia has been found to be one of the most important contributing factors. Appropriate lifestyle changes along with proper drug therapy lead to a considerable reduction in mortality rate due to coronary artery disease. Reduction of LDL Cholesterol is the primary goal of cholesterol-lowering therapy, but most of the patients are usually unable to achieve the treatment goals with lifestyle modifications alone; and in such situations, drug therapy is essential to prevent the disease progression and further future complications. The aim of the study was to demonstrate impact of three moderate intensity statins on lipid profile and biomarker representing muscle toxicity. It was a prospective observational study conducted in a tertiary care teaching hospital in south India. Patients of both gender falling the age group between 30 and 70 years with newly diagnosed Hyperlipidemia attending the Department of Medicine OPD, were enrolled in the study. Total 229 participants were enrolled in study and all the drug treatment were found to be effective in achieving the treatment goal; at the same time Rosuvastatin 10 mg treatment group exhibited better efficacy along with minimal muscle toxicity.

An Epidemiological Assessment of Endometrial Carcinoma Including Demographics and Histopathological Correlation, from a Tertiary Care Teaching Hospital in South India

2021 ◽  
Vol 8 (30) ◽  
pp. 2751-2756
Author(s):  
Jeenu Babu ◽  
Reeba George Pulinilkunnathil ◽  
Bindu R. Kumar
Keyword(s):  
Risk Factors ◽  
Endometrial Carcinoma ◽  
Teaching Hospital ◽  
South India ◽  
Tertiary Care ◽  
Endometrial Biopsy ◽  
Prognostic Indicators ◽  
Histopathological Correlation ◽  
History Of ◽  
The Mean

BACKGROUND Endometrial cancer (EC) is also the second most common gynaecologic malignancy in developing countries, with an incidence of 5.9 per 100,000 women. Due to the multiple modifiable factors, a better understanding of the prognostic indicators can lead to early detection and treatment. The purpose of this study was to evaluate the frequency and the distribution of various risk factors, epidemiological factors, and histological patterns of patients diagnosed with endometrial carcinoma in a tertiary teaching hospital in south India and compare them with similar studies. The compiled findings of 60 consecutive cases that presented to our tertiary care teaching hospital in Kerala, south India, over oneand-a-half-year period were studied. METHODS This study was essentially an ex post facto retrospective study done on 60 patients for one and half years. Retrospective data collection and compilation were done with previously prepared structured questionnaires in patients with histologically proven endometrial carcinoma. All cases were subjected to hysterectomy with post-surgical histopathology correlation. A study of the risk factors, general epidemiological characteristics, endometrial biopsy findings, and post-surgical histopathology was done. RESULTS The mean age at presentation was 59.83 years. The mean age of menarche was 13.72 years, and menopause was 49.42 years. The majority of patients were married, multiparous, and presented with bleeding per vaginum (77 %). 61.7 % of the patients had a history of hypertension, 31.7 % had a history of hypothyroidism, and 43.3 % had a history of diabetes mellitus in the study population. The most common histopathological type by endometrial biopsy and histopathological correlation was endometrioid adenocarcinoma (88.3 %). CONCLUSIONS Postmenopausal age group, with early menarche and late menopause, high body mass index (BMI), thickened endometrium on ultrasound, and atrophic uterus were some of the features associated with endometrial carcinoma. The most common histological subtype was found to be endometrioid carcinoma KEYWORDS Endometrial Carcinoma, Risk Factors, Prognostic Indicators

Validation of surgical APGAR score in abdominal surgeries at a tertiary care teaching hospital in South India

2021 ◽  
Vol 10 (2) ◽  
pp. 85
Author(s):  
Aloka Samantaray ◽  
KYadhu Bhushanam ◽  
Kaarthika Thottikat ◽  
Hemalatha Pasupuleti ◽  
RSri Devi ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
Apgar Score ◽  
South India ◽  
Tertiary Care ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Surgical Apgar Score

scholarly journals Morphological spectrum of atherosclerotic lesions in a tertiary care Institute in Punjab

2018 ◽  
Vol 10 (1) ◽  
pp. 19-24
Author(s):  
Rajiv Kumar Gupta ◽  
Ruchita Tyagi ◽  
Vikrampal Singh ◽  
Samir Kapoor ◽  
Gurmeet Singh ◽  
...  
Keyword(s):  
Coronary Artery ◽  
South Asians ◽  
Tertiary Care ◽  
Disease Process ◽  
Heart Association ◽  
Lifestyle Changes ◽  
Female Ratio ◽  
Fibrous Cap ◽  
Atherosclerotic Lesions ◽  
Morphological Studies

Background: The incidence of coronary artery disease (CAD) has risen considerably in developing world due to industrialization, urbanisation and lifestyle changes, especially among Indians and South Asians. The onset of CAD has been seen to occur at an early age and the severity of the disease and mortality associated with CAD has also increased. The pathology of atherosclerosis needs to be re-evaluated to develop targeted therapy which can contain the disease process at the earliest stage. Aims and Objectives: Most of the morphological studies on atherosclerosis have been done on autopsy cases. In this study, we have analysed the morphological spectrum of atherosclerotic lesions in live patients. Materials and Methods:  We retrospectively analysed the histopathology slides of 85 cases whose endarterectomy plaques were received in the Department of Pathology over a period of three and half years (January 2014 to June 2017) and classified the lesions according to Modified American Heart Association classification of atherosclerosis. Results: The average age of patients was 60 years and male to female ratio of 4.3:1. Left anterior descending artery was the commonest vessel involved (52.4%). Majority of the cases had fibrocalcific plaques,followed by fibrous cap atheroma and calcified nodules. Conclusion: Coronary artery plaques were found even in patients less than 40 years old.  Aggressive lipid defense therapy needs to be the cornerstone of management of CAD.

Epidemiology of burn injuries in a Tertiary Care Teaching Hospital in South India

2018 ◽  
Vol 12 (4) ◽  
pp. 206 ◽  
Author(s):  
Priya Tiwari ◽  
T.C. Kavitha ◽  
Rajesh Kamath ◽  
Brayal D'Souza ◽  
V R Roja ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
South India ◽  
Tertiary Care ◽  
Burn Injuries ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching
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