scholarly journals Epidemiological Study and Associated Risk Factors for Developing Bacterial Meningitis in Children of Odisha, India

2021 ◽  
pp. 107-115
Author(s):  
C. P. Khuntia ◽  
S. K. Kar ◽  
B. Dwibedi
Keyword(s):  
Risk Factors ◽  
Bacterial Meningitis ◽  
Haemophilus Influenzae Type ◽  
Care Hospital ◽  
Type B ◽  
Rt Pcr ◽  
Under Five ◽  
Cell Counts ◽  
Mother’S Education ◽  
Mother's Education

Background: Bacterial meningitis is a leading cause of high childhood transience. It is the foremost cause of fatality in pediatric age group of 0-5 years in India accounting 0.5 to 2.6% of hospital admissions with CFR 16-30%. Based on above scenario, the study was undertaken to address the prevalence, etiology, social determinants of health factors of bacterial meningitis among under five children Odisha, India. Methods: A cross sectional study comprising of children under five years of age admitted to tertiary care hospital and teaching institutions in Cuttack with suspected clinical diagnosis of bacterial meningitis during April, 2012 to September 2013. About 634 children enrolled into the study after getting appropriate consent from parents or their legal guardians. Lumbar puncture was done and CSF was sent for biochemical analysis, cell counts, staining, culture, latex agglutination test (LAT) and real time polymerase chain reaction (RT PCR). Results: About 61 children (10.4%) were confirmed with diagnosis of bacterial meningitis by either culture, latex or RT PCR.  Male children (74.7%) were significantly more prone to bacterial meningitis than females (24.3%). The common isolated pathogens were Streptococcus pneumonia, Haemophilus influenza type b, E. coli, Pseudomonas aeruginosa, Klebseilla pneumoniae and Staphylococcus aureus. Streptococcus pneumoniae was observed to be most common pathogen (57.6%) followed by Haemophilus influenzae type b (26.2%). The risk factors analyzed showed statistically significant association (p<0.01) with low household income, mother’s education, overcrowding (more than 3 persons in a single room), smoking and poor ventilation of household. Conclusion: Strengthening early detection of bacteria meningitis by rapid diagnostic test like LATEX, RT PCR and prompt treatment of emergent case at the household level, improvement in mother’s education and awareness, transportation to local hospital and facility for treatment and care should be utmost priority in the present scenario. It is crucial to assess the burden of bacterial meningitis with its etiology is in this region as  vaccines are yet to be introduced in the child vaccine program.

scholarly journals Socioeconomic and Demographic Determinants of Body Mass Index in Sudan: A Predictive Model

2021 ◽  
Vol 14 (1) ◽  
pp. 478-483
Author(s):  
Ahmed Abdallah ◽  
Mohammed Mohammed ◽  
Dawit Ayele
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Multinomial Logistic Regression ◽  
Wealth Index ◽  
Normal Weight ◽  
Children Under Five ◽  
Under Five ◽  
Body Mass Index Status ◽  
Mother’S Education ◽  
Mother's Education

Background: This paper aimed to determine the socioeconomic and demographic determinants related to Body Mass Index (BMI) for children under five years in Sudan. The objective of the study was to identify the factors of BMI for under-five children. Methods: This study used the Sudan Multiple Indicator Cluster Survey (MICS) conducted in the year 2014. The multinomial logistic regression model was adopted. Results: Results revealed that the prevalence of underweight infants under five years was 86.3% in females and 85.3% in males, while the proportion of the normal weight of infants under five years of age for males was slightly higher than females; there was a correlation amid geographic determinants, state, and BMI status. Also, there was a significant association between the mother’s education and body mass index status and the wealth index and body mass index status. The variables place of residence and sex did not show a statistically significant relationship with body mass index status for children under five years of age in Sudan. Conclusion: The risk factors significantly associated with body mass were the state, whether the child had ever been breastfed, sex, mother’s education, wealth index, and age in the month.

Sequelae of Acute Bacterial Meningitis in Children Treated for Seven Days

PEDIATRICS ◽  
1986 ◽  
Vol 78 (1) ◽  
pp. 21-25
Author(s):  
T. Jadavji ◽  
W. D. Biggar ◽  
R. Gold ◽  
C. G. Prober
Keyword(s):  
Hearing Loss ◽  
Bacterial Meningitis ◽  
Haemophilus Influenzae Type ◽  
Acute Bacterial Meningitis ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Speech Defect ◽  
Intravenous Antibiotic ◽  
Severe Handicaps ◽  
Meningitis In Children

The sequelae of acute bacterial meningitis in children who were treated with ampicillin or chloramphenicol for seven days during the period January 1979 to June 1983 were assessed prospectively. The 235 patients (117 boys and 118 girls) ranged in age from four days to 18 years (mean 26.4 months). Haemophilus influenzae type b was isolated in 70% of patients, Streptococcus pneumoniae in 20%, and Neisseria meningitidis in 10%. The mortality rate was 6.4%. No relapses occurred. Of the 220 survivors, 171 had neurologic psychometric, audiologic, and ophthalmologic assessments performed for a minimum of 1 year following their illness. One hundred thirty-six (80%) children had no detectable sequelae; 20% had mild to severe handicaps. The frequency of sequelae was greatest among children with S pneumoniae meningitis (57%) and least among children with N meningitidis (0%). The sequelae observed included: sensorineural hearing loss (12.9%), developmental delay (5.3%), speech defect (4.7%), motor defect (3.0%), hydrocephalus (1.7%), and seizure disorder (1%). The frequency of observed sequelae among these patients is similar to that previously reported in children treated for ten to 14 days. Our findings indicate that seven days of intravenous antibiotic therapy is adequate for the treatment of bacterial meningitis in children.

Vaccination with Haemophilus influenzae type b conjugate vaccine reduces bacterial meningitis in Morocco

Vaccine ◽  
2012 ◽  
Vol 30 (15) ◽  
pp. 2594-2599 ◽  
Author(s):  
Mohamed Braikat ◽  
Abdelaziz Barkia ◽  
Naima El Mdaghri ◽  
Jeanette J. Rainey ◽  
Adam L. Cohen ◽  
...  
Keyword(s):  
Bacterial Meningitis ◽  
Haemophilus Influenzae ◽  
Conjugate Vaccine ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B

scholarly journals Clinical characteristics and factors influencing the outcome of hospitalised COVID-19 patients in a semi-urban primary healthcare center

2021 ◽  
Vol 14 (2) ◽  
pp. 42-54
Author(s):  
Wasim Md Mohosin Ul Haque ◽  
Chinmay Saha Podder ◽  
Nandini Chowdhury ◽  
Md Mohim Ibne Sina ◽  
SKM Shameem Kawser ◽  
...  
Keyword(s):  
Risk Factors ◽  
Adverse Outcome ◽  
Severe Disease ◽  
Tertiary Care ◽  
Chronic Obstructive ◽  
Care Hospital ◽  
Rt Pcr ◽  
District Health ◽  
Factors Associated ◽  
Negative Outcome

Background and objectives: Various new manifestations and risk factors for COVID-19 have been unveiled in the course of the current pandemic. Understanding the clinical spectrums as well as the risk factors associated with the adverse outcome of the disease is critical to combat this pandemic. This study was conducted to identify the clinical features, overall outcome and the factors associated with adverse outcome of the hospitalised COVID-19 patients in a semi-urban healthcare setting. Methods: This study was conducted at Debidwar Upazila (sub-district) Health Complex under the Cumilla district from April 2020 to October 2020. Reverse transcriptase-polymerase chain reaction (RT-PCR) positive COVID-19 patients, aged 18 years and above, admitted at the Health Complex were enrolled in the study. All patients were followed till their recovery, referral or death. The data were collected in a pre-designed semi-structured questionnaire that included demographic, epidemiological, clinical and laboratory parameters. Result: Out of 50 RT-PCR positiveCOVID-19 adult participants, 30 (60%) were males and 20 (40%) were females. Twenty-four percent, 36%, and 40% of the patients had mild, moderate and severe disease respectively. The most common clinical symptom was fever (96%), followed by cough (86%) and shortness of breath (60%). Hypertension (54%), diabetes mellitus (40%), bronchial asthma (20%) and chronic obstructive pulmonary disease (COPD, 14%) were the major co-morbid conditions. Of the total cases, 2 (4%) died and 8 (16%) required referral to tertiary care hospital while 40 (80%) recovered. COPD was associated with poor outcome (OR 19; 95% CI: 2.88, 125.31; p < 0.05). Smokers were 7 times more likely to exhibit the negative outcome than non-smokers (95% CI: 1.52, 32.33; p < 0.05). Conclusion: In this study, COPD was associated with a negative outcome. Further study with larger sample should be carried out to determine the spectrum of risk factors. Ibrahim Med. Coll. J. 2020; 14(2): 42-54

Onset of Hearing Loss in Children with Bacterial Meningitis

PEDIATRICS ◽  
1984 ◽  
Vol 73 (5) ◽  
pp. 575-578
Author(s):  
Sheldon L. Kaplan ◽  
Francis I. Catlin ◽  
Toni Weaver ◽  
Ralph D. Feigin
Keyword(s):  
Bacterial Meningitis ◽  
Auditory Brainstem ◽  
The Other ◽  
Auditory Brainstem Responses ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Repeat Testing ◽  
Brainstem Dysfunction ◽  
High Risk Children

Auditory brainstem responses were evaluated in 37 children with bacterial meningitis within 48 hours of admission. Four children (two with Haemophilus influenzae type b, and two with Streptococcus pneumoniae) had definite abnormalities of hearing detected at admission. Two of these children had severe-to-profound hearing losses which have persisted. Hearing losses were greatly reduced in the other two children (one child also was ataxic) when repeat testing was performed. Auditory brainstem responses in two additional children suggested brainstem dysfunction at admission (one child died and the other has had severe sequelae). Hearing losses occur early in the course of bacterial meningitis in some children. Further studies are required to confirm the use of auditory brainstem responses in detecting hearing losses early in high-risk children with bacterial meningitis.

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