scholarly journals Evaluation of Anastomotic Leakages Grading System Following Anterior Resection for Rectal Cancer

Author(s):  
Yizhou Huang ◽  
Xulei Qi ◽  
MinHao Yu ◽  
Hao Wang ◽  
Enda Yu ◽  
...  

Objective Anastomotic leakage (AL) is generally accepted as a major complication of rectal resection surgery. In our study, we aimed to validate its present definition and grading system which were proposed by International Study Group of Rectal Cancer (ISREC) in 2010. Methods Patients who underwent rectal anterior resection in two colorectal surgery centers from January 2012 to December 2014 were included and categorized into different groups according to the ISREC criteria, further, the rate, the severity and the clinical outcomes of their AL were analyzed and compared. Results During a median follow-up period of 38.9 months, 984 patients were included in total. The overall AL rate was 5.0% (49/984), including 7 (14.0%) grade A patients, 21 (43.0%) grade B patients and 21 (43.0%) grade C patients. The rate of grade C AL in protective diverting stoma group was significantly lower than the one in non-stoma group (0.6% vs 2.8%, P=0.029). Patients with grade B or grade C AL had much longer hospital stay than grade A AL patients (P=0.016). The overall 3-year survival rates of grade A, B and C group were 83.3%, 66.7% and 55.6% respectively, without statistical significance. Conclusions Patients who were divided into different groups according to the grading system proposed by the ISREC criteria had significantly different symptoms, clinical outcomes, management and duration of hospitalization. Our study supported that the ISREC criteria which was proved to be applicable to complete surgical outcome assessment and quality assurance of rectal resection surgery.

Surgery ◽  
2010 ◽  
Vol 147 (3) ◽  
pp. 339-351 ◽  
Author(s):  
Nuh N. Rahbari ◽  
Jürgen Weitz ◽  
Werner Hohenberger ◽  
Richard J. Heald ◽  
Brendan Moran ◽  
...  

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e75519 ◽  
Author(s):  
Zhi-Jie Cong ◽  
Liang-Hao Hu ◽  
Zheng-Qian Bian ◽  
Guang-Yao Ye ◽  
Min-Hao Yu ◽  
...  

2002 ◽  
Vol 168 (5) ◽  
pp. 297-301 ◽  
Author(s):  
Nigel A. M. Chatwin ◽  
Michel Ribordy ◽  
Jean C. Givel

2015 ◽  
Vol 87 (3) ◽  
Author(s):  
Jerzy Piecuch ◽  
Maciej Wiewióra ◽  
Monika Szrot ◽  
Janusz Jopek ◽  
Albert Krzak ◽  
...  

AbstractAnterior resection for rectal cancer carries the risk of serious complications, especially fistulas at the site of anastomosis. Numerous factors have been shown to impact anastomotic leakage. The results of studies on the influence of obesity on the frequency of anastomotic leakage after rectal resection performed due to cancer have been contradictory.The aim of the study was to evaluate the relationship between body mass index (BMI) and frequency of anastomotic leakage after anterior rectal resection performed due to cancer. Material and methods. This retrospective analysis included 222 subsequent patients who had undergone anterior resection due to cancer with an anastomosis formed with a mechanical suture. The patients were divided into 3 groups depending on their BMI quartile as follows: Group I, BMI < 23.8 kg/mResults. Anastomotic leakage occurred in 8 (3.6%) patients. Fistulas occurred in 4 out of 61 patients (6.56%) in group I, which was the highest incidence of fistulas for all 3 groups. In group II, fistulas occurred in 2 out of 55 patients (3.63%), and similarly, in group III, they occurred in 2 out of 106 patients (1.87%). The differences found in the frequency of fistulas between groups were not statistically significant (p=0.31). The logistic regression analysis did not show any relationship between leakage and age (p = 0.55; OR = 1.02; 95% CI: 0.95 - 1.1), sex (p = 0.97; OR = 0.97; 95% CI: 0.22 - 4.25) or BMI (p = 0.27; OR = 0.58; 95% CI: 0.22 - 1.53).Conclusions. The results of our study show that BMI did not have any influence on the frequency of anastomotic leakage after anterior rectal resection performed due to cancer.


2017 ◽  
pp. 36-40
Author(s):  
Vinh Quy Truong ◽  
Anh Vu Pham ◽  
Quang Thuu Le

Purpose: To evaluate the functional outcome of sphincter-preserving rectal resection for low rectal cancer. Materials and Methods: From April 2009 to January 2016, there are 52 patients who underwent sphincter-preserving rectal resection with total mesorectal excision with low rectal cancer (<6cm from the anal verge) at Hue Central Hospital, Hue, Vietnam. Results: the average age 62.7 ± 12.8, the distance of tumor from anal verge include four group (≤ 3cm 1.9%; 3 to ≤ 4cm 17.3%; 4 to ≤ 5cm 34.6%; > 5 cm). T stage T1/ T2/T3: 1.9%/28.8%/69.2%. The following time is 33.8 ± 18.9 month. Overall recurrence was 13/18(27.1%), local recurrence was 5 (10.4%). Total survival was 40.5 ± 2.9 month. Technique: intersphincteric preservation 14 (26.9%), low anterior resection 17 (32.7%) and pull-through procedure 21 (40.4%). The distance of anatomosis from anal verge: from 1 to ≤ 2 cm:14 (26.9%); from 2 to ≤ 3cm: 21 (40.4%); from 3 to ≤ 4 cm: 17 (32.7%). Bowels movement of 3 month: 4.7 ± 3.2 and 12th month: 2.7 ± 1.6 (p< 0.01). Conclusions: Sphincterpreserving rectal resection using may provide a good continence and oncologic safety. The patients are acceptable with the results of functional outcomes. Key words: Low rectal cancer, sphincter-preserving


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