scholarly journals Hepatitis A Virus and Hepatitis E Virus Infection in Adult Patients From A Tertiary Care Hospital of North India

2016 ◽  
Vol 15 (07) ◽  
pp. 06-08
Author(s):  
A.K. Sharma ◽  
U. Dutta ◽  
S.K. Sinha ◽  
R. Kochhar
Esculapio ◽  
2020 ◽  
Vol 16 (03, july 2020-Septmber 2020) ◽  
Author(s):  
Rukhsana Gulzar ◽  
Rehma Dar ◽  
Qurat ul Ain ◽  
Humair Ahmad ◽  
Syed Saqib Ali ◽  
...  

Objective: To study the frequency of Hepatitis A Virus and Hepatitis E Virus infections in adult patients of acute hepatitis in a Tertiary Care Hospital in Lahore. Methods: All samples received from medical units (indoor and outdoor) of Mayo hospital Lahore from 26 Feb.2019 to 26.Sept.2019, for Hepatitis A & E IgM antibody testing by ELISA were included in the study. The results and other relevant information were recorded on proforma. Results: Out of 690 study subjects, 62% were male and 38% were female. The mean age ± SD was 33.8 + 7.4years. The percentage of HAV or HEV infected cases was 59%,and 41% were not infected with HAV or HEV. The frequency and percentage of Hepatitis AVirus was 62(15%),whereas the frequency and percentage of HEV was 327(80%) and that of co-infection with HAV and HEV was 21(5%). The mean + SD age of Hepatitis AVirus was 35.2 + 5.0,whereas the mean + SD age of Hepatitis E Virus and co-infection with Hepatitis A and Hepatitis E Virus were 31.45 + 2.3 and 22.6 + 6.3 years, respectively. Conclusion: Hepatitis E Virus is the commonest cause of acute hepatitis in our study,followed by hepatitis A Virus and coinfection of HAV and HEV. Key words: Frequency, Hepatitis A infection, Hepatitis E infection, Co- infection Hepatitis A & Hepatitis E.


2019 ◽  
Vol 150 (5) ◽  
pp. 508
Author(s):  
D Himanshu ◽  
Sanshriti Chauhan ◽  
Jyotsna Agarwal ◽  
Amita Jain ◽  
KK Sawlani ◽  
...  

2014 ◽  
Vol 4 ◽  
pp. S10-S11
Author(s):  
Arun Kumar Sharma ◽  
Uma Debi ◽  
Babu Ram Thapa ◽  
Rakesh Kochhar ◽  
Deepak Kumar Bhasin

2019 ◽  
Vol 6 (2) ◽  
pp. 588 ◽  
Author(s):  
Shikha Handa ◽  
Sanober Wasim ◽  
B. P. Kalra ◽  
Anil Rawat ◽  
Vipan Chandar ◽  
...  

Background: Hepatitis-A virus (HAV) and Hepatitis E virus (HEV) are two major hepatotropic viruses of great public health importance in the developing countries like India. Both HAV and HEV are enterically transmitted and there are speculations that their co-infection might be associated with a more severe clinical course and increased rate of mortality. The objective of this study is to determine the prevalence, clinical features and biochemical parameters of Hepatitis A and Hepatitis E co-infection in hospitalized patients at a tertiary care centre in Uttarakhand.Methods: It is a retrospective study, covering a period of 4years and conducted in Himalayan Institute of Medical Sciences, SRHU Jolly Grant, Dehradun. Records of the patients with Hepatitis A and Hepatitis E co-infection were retrieved and analyzed.Results: Out of total 125 patients of acute viral hepatitis, 13 patients had HAV and HEV co-infection. 100% of the patients with co-infection presented with complaints of fever and jaundice, followed by 76.92% with vomiting, 69.23% with pruritis, 61.53% with pain in abdomen and 23.07% with altered sensorium. Mean Bilirubin, ALT, AST were 8.69±7.27 mg/dl, 2030.69±1726.93IU/L and 1880.07±1881.11IU/L respectively. Average duration of stay was 8.2 days. Encephalopathy was seen in 2 patients. However, no mortality was reported.Conclusions: Co-infection of HAV and HEV is not rare in pediatric age group. Knowledge about this will be of immense help for planning of future vaccination strategies and for better sanitation program in developing countries like India.


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