Seroprevalence of Hepatitis A virus (HAV) and Hepatitis E virus (HEV) in the patients presenting with acute viral hepa- titis at a tertiary care hospital Rajkot

Objective: To study the frequency of Hepatitis A Virus and Hepatitis E Virus infections in adult patients of acute hepatitis in a Tertiary Care Hospital in Lahore. Methods: All samples received from medical units (indoor and outdoor) of Mayo hospital Lahore from 26 Feb.2019 to 26.Sept.2019, for Hepatitis A & E IgM antibody testing by ELISA were included in the study. The results and other relevant information were recorded on proforma. Results: Out of 690 study subjects, 62% were male and 38% were female. The mean age ± SD was 33.8 + 7.4years. The percentage of HAV or HEV infected cases was 59%,and 41% were not infected with HAV or HEV. The frequency and percentage of Hepatitis AVirus was 62(15%),whereas the frequency and percentage of HEV was 327(80%) and that of co-infection with HAV and HEV was 21(5%). The mean + SD age of Hepatitis AVirus was 35.2 + 5.0,whereas the mean + SD age of Hepatitis E Virus and co-infection with Hepatitis A and Hepatitis E Virus were 31.45 + 2.3 and 22.6 + 6.3 years, respectively. Conclusion: Hepatitis E Virus is the commonest cause of acute hepatitis in our study,followed by hepatitis A Virus and coinfection of HAV and HEV. Key words: Frequency, Hepatitis A infection, Hepatitis E infection, Co- infection Hepatitis A & Hepatitis E.

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Seroprevalence of hepatitis A virus and hepatitis E virus among the patients presenting with acute viral hepatitis admitted in a tertiary care center located in Central India

Menoufia Medical Journal ◽

10.4103/mmj.mmj_153_20 ◽

2021 ◽

Vol 34 (2) ◽

pp. 582

Author(s):

Trupti Bajpai ◽

Prachi Shaw ◽

Maneesha Pandey ◽

Jinwal Meena ◽

Neelesh Gagrani

Keyword(s):

Viral Hepatitis ◽

Hepatitis E Virus ◽

Hepatitis A ◽

Acute Viral Hepatitis ◽

Hepatitis A Virus ◽

Care Center ◽

Tertiary Care ◽

Central India ◽

Hepatitis E ◽

Tertiary Care Center

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Clinico-epidemiological profile of hepatitis A virus and hepatitis E virus co-infection in pediatric age group: a hospital based retrospective study

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20190692 ◽

2019 ◽

Vol 6 (2) ◽

pp. 588 ◽

Cited By ~ 1

Author(s):

Shikha Handa ◽

Sanober Wasim ◽

B. P. Kalra ◽

Anil Rawat ◽

Vipan Chandar ◽

...

Keyword(s):

Developing Countries ◽

Retrospective Study ◽

Hepatitis E Virus ◽

Hepatitis A ◽

Hepatitis A Virus ◽

Tertiary Care ◽

Hepatitis E ◽

Age Group ◽

Pediatric Age ◽

Pediatric Age Group

Background: Hepatitis-A virus (HAV) and Hepatitis E virus (HEV) are two major hepatotropic viruses of great public health importance in the developing countries like India. Both HAV and HEV are enterically transmitted and there are speculations that their co-infection might be associated with a more severe clinical course and increased rate of mortality. The objective of this study is to determine the prevalence, clinical features and biochemical parameters of Hepatitis A and Hepatitis E co-infection in hospitalized patients at a tertiary care centre in Uttarakhand.Methods: It is a retrospective study, covering a period of 4years and conducted in Himalayan Institute of Medical Sciences, SRHU Jolly Grant, Dehradun. Records of the patients with Hepatitis A and Hepatitis E co-infection were retrieved and analyzed.Results: Out of total 125 patients of acute viral hepatitis, 13 patients had HAV and HEV co-infection. 100% of the patients with co-infection presented with complaints of fever and jaundice, followed by 76.92% with vomiting, 69.23% with pruritis, 61.53% with pain in abdomen and 23.07% with altered sensorium. Mean Bilirubin, ALT, AST were 8.69±7.27 mg/dl, 2030.69±1726.93IU/L and 1880.07±1881.11IU/L respectively. Average duration of stay was 8.2 days. Encephalopathy was seen in 2 patients. However, no mortality was reported.Conclusions: Co-infection of HAV and HEV is not rare in pediatric age group. Knowledge about this will be of immense help for planning of future vaccination strategies and for better sanitation program in developing countries like India.

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A study of serum electrolytes level in viral hepatitis E patients in a tertiary care hospital of south Gujarat

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20214133 ◽

2021 ◽

Vol 8 (11) ◽

pp. 1710

Author(s):

Ravi Shah ◽

Parshv Shah ◽

Hemant Shah ◽

Nilesh Doctor

Keyword(s):

Viral Hepatitis ◽

Hepatitis E Virus ◽

Total Bilirubin ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Hepatitis E ◽

Cross Sectional Study ◽

Care Hospital ◽

Single Centre ◽

Cross Sectional

Background: the aim of the study was to find and understand the relation between electrolytes and viral hepatitis E. To study electrolyte abnormality in patients with hepatitis E virus (HEV).Methods: This study is a single centre cross sectional study on the patients with HEV infection. Consecutive cases affected with HEV-at department of medicine, SMIMER (Surat Municipal institute of medical education and research) hospital, Surat during the period of 1 year (July-2019 to June-2020) are taken up for the study.Results: Abnormal electrolytes are associated with higher mortality in patients infected with HEV.Conclusions: A higher mean serum creatinine, total bilirubin, SGOT, SGPT; lower total protein, albumin, and abnormal electrolytes in body fluid (Na+, K+, Cl-, Ca++) values are associated with higher mortality in patients infected with HEV.

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