low ambient temperature
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Author(s):  
Yifeng Qian ◽  
Ya Gao ◽  
Binxin Cai ◽  
Wenbin Zhang ◽  
Xudong Wang ◽  
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2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Xi-Yao Chen ◽  
Yang Jiao ◽  
Fu-Yang Zhang

AbstractThe present study demonstrates that the down-regulation of peroxisome proliferator-activated receptor-α (PPARα) results in chronic low ambient temperature (LT) exposure-induced cardiac dysfunction and remodeling, emphasizing the therapeutic potential of PPARα activation strategies (e.g. fenofibrate treatment) in LT-associated cardiac injury.


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