Plexcitonic strong coupling: unique features, applications, and challenges

There are, recently, remarkable achievements in turning light-matter interactions into strong coupling quantum regime. In particular, room temperature plexcitonic strong coupling in plasmon-exciton hybrid systems can bring promising benefits for fundamental and applied physics. Herein we will review theoretical insights and recent experimental achievements in plexcitonic strong coupling and divide this review into two main parts. The first part will briefly introduce the general field of strong coupling, including its origin and history, physical mechanisms and theoretical models, as well as recent advanced applications of strong coupling, such as the quantum or biochemical devices enabled by optical strong coupling. The second part will zoom in and concentrate on plexcitonic strong coupling by introducing its unique features and new potentials (such as single-particle ultrastrong coupling, strong coupling dynamics in femtosecond scale) and discussing the limitations and challenges of plexcitonic strong coupling, which will also be accompanied by potential solutions such as the microcavity-engineered plexcitonics, spectral hold burning effects, and metamaterial-based strong coupling. Finally, we will summarize and conclude this review, highlighting the future research directions and promising applications.

Cardiac Cell Patterning on Customized Microelectrode Arrays for Electrophysiological Recordings

Cardiomyocytes (CMs) and fibroblast cells are two essential elements for cardiac tissue structure and function. The interactions between them can alter cardiac electrophysiology and thus contribute to cardiac diseases, such as arrhythmogenesis. One possible explanation is that fibroblasts can directly affect cardiac electrophysiology through electrical coupling with CMs. Therefore, detecting the electrical activities in the CM-fibroblast network is vital for understanding the coupling dynamics among them. Current commercialized platforms for studying cardiac electrophysiology utilize planar microelectrode arrays (MEAs) to record the extracellular field potential (FP) in real-time, but the prearranged electrode configuration highly limits the measurement capabilities at specific locations. Here, we report a custom-designed MEA device with a novel micropatterning method to construct a controlled network of neonatal rat CMs (rCMs) and fibroblast connections for monitoring the electrical activity of rCM-fibroblast co-cultures in a spatially controlled fashion. For the micropatterning of the co-culture, surface topographical features and mobile blockers were used to control the initial attachment locations of a mixture of neonatal rat cardiomyocytes (rCMs) and fibroblasts, to form separate beating rCM-fibroblast clusters while leaving empty space for fibroblast growth to connect these clusters. Once the blockers are removed, the proliferating fibroblasts connect and couple the separate beating clusters. Using this method, electrical activity of both rCMs and human-induced-pluripotent-stem-cell-derived cardiomyocytes (iCMs) was examined. The coupling dynamics were studied through the extracellular FP and impedance profile recorded from the MEA device, indicating that the fibroblast bridge provided an RC-type coupling of physically separate rCM-containing clusters and enabled synchronization of these clusters.

Plasmon-Enhanced Ultraviolet Photoluminescence from the Graphene/GaN Nanofilm

The response of graphene surface plasmon (SP) in ultraviolet (UV) wavelength region and its functional applications on the short wavelength of graphene/semiconductorare both fascinating research areas. Herein, a hybrid structure of graphene/GaN nanofilm was designed and fabricated to investigate the photoluminescence (PL) performance and the coupling dynamics. It is demonstrated that the resonant coupling between graphene SPs and GaN exciton emission is responsible for the substantially enhanced PL from the structure of graphene/GaN nanofilm. The underlying mechanism of the improved PL performance was proposed based on theoretical simulation and experimental characterization. The results are helpful to design new types of optic and photoelectronic devices based on SP coupling in graphene/semiconductor hybrid structures.