Hermeneutische Überlegungen zu Heideggers schwarzen Heften und zum neudenken seines Denkwegs II.

"Hermeneutical Considerations on Heidegger’s Black Notebooks and on the Revisiting of his Path of Thinking II. Starting with preliminary philological-hermeneutical considerations concerning the way Heidegger’s Black Notebooks can and should be dealt with, as well as concerning the question of what tasks may be derived from them for future research, the paper attempts to discuss the Black Notebooks applying a variety of methods and approaches. Themes that are discussed at more or less length include: Time factor and the formulation of our task; explanation and understanding or the way a philosophical path should be approached and dealt with methodically (hermeneutically); the theme related to “Heidegger and anti-Semitism” and the question concerning individuality; prejudices from a hermeneutical perspective and the way to deal with them; relapses and their philosophical explanation; insufficient and exaggerated sensibility; Heidegger and Hegel; equivocality and the dark side of the “formal indication”; Lukács, Scheler and the devil; Heidegger’s great being-historical treatises and their greatness; suggestions for a reconsideration of Heidegger’s way of thinking. – One important hermeneutical claim brought to bear on the various discussions is this: just as it would be inappropriate in our dealing with Heidegger’s texts to disregard Heidegger’s own self-interpretations, it would be no less inappropriate to consider those self-interpretations – which themselves call for interpretation – as telling us the sole and ultimate truth. This second part of the paper dedicates special attention to the question of re-examining Heidegger’s whole philosophical itinerary in the light of the Black Notebooks. Keywords: hermeneutics, being, history, interpretation, individuality "

Hermeneutische Überlegungen zu Heideggers Schwarzen Heften und zum Neudenken Seines Denkwegs (I)

"Hermeneutical Considerations on Heidegger’s Black Notebooks and on the Revisit-ing of his Path of Thinking I. Starting with preliminary philological-hermeneutical considerations concerning the way Heidegger’s Black Notebooks can and should be dealt with, as well as concerning the question what tasks may be derived from them for future research, the paper attempts to discuss the Black Notebooks ap-plying a variety of methods and multiple approaches. Themes that are discussed at more or less length include: Time factor and the formulation of our task; explana-tion and understanding or the way a philosophical path should be approached and dealt with methodically (hermeneutically); the theme related to “Heidegger and anti-Semitism” and the question concerning individuality; prejudices from a her-meneutical perspective and the way to deal with them; relapses and their philo-sophical explanation; missing and increased sensibility; Heidegger and Hegel; equivocality and the dark side of the “formal indication”; Lukács, Scheler and the devil; Heidegger’s great being-historical treatises and their greatness; suggestions for a reconsideration of Heidegger’s way of thinking. -- One important hermeneu-tical claim brought to bear on the various discussions is this: just as it would be in-appropriate in our dealing with Heidegger’s texts to disregard Heidegger’s own self-interpretations, it would be no less inappropriate to consider those self-interpretations--which themselves call for interpretation--as telling us the sole and ultimate truth. Keywords: hermeneutics, being, history, interpretation, individuality "

Heidegger’s Endoxic Method

I argue that Heidegger’s methodological breakthrough in the early 1920s, the development of hermeneutic phenomenology, and the structure of Being and Time are the result of Heidegger’s appropriation of Aristotle’s philosophical method in his Physics and Nicomachean Ethics. In part one, I explain the general structure of Aristotle’s method and demonstrate the distinction between scientific and philo­sophical investigations. In part two, I show how formal indication and phenomenological destruction are the product of Heidegger’s reading of Aristotle’s method by demonstrating their affinity in approach, content, and criteria for success. Lastly, in part three, I show how aspects of Being and Time, specifically das Man and the destruction of history, become more intelligible when framed in terms of an Aristotelian investigation into endoxa.

Hereditary transthyretin amyloidosis: predictors of conduction disease

Introduction Pacemakers are frequently needed due to a high prevalence of conduction disease in mutated ATTR amyloidosis (mATTR). We aimed to identify the variables associated with the need of pacemaker implantation in this population. Methods We retrospectively studied 255 patients with suspicion of heart involvement of mATTR observed at our cardiology clinic during the last year. Clinical and outcome data were retrieved by chart review. We have defined the need for pacemaker implantation as: 1) the formal guidelines indications or 2) Ventricular pacing >10% in patients who had prophylactic pacemaker implantation prior to liver transplantation (LT). This way, we have defined 3 different groups: group 1: patients with no evidence of conduction disease; group 2: patients with conduction disease, but no formal indication for pacemaker implantation; and group 3: patients with formal indication for pacemaker implantation or ventricular pacing >10% in patients who had prophylactic pacemaker implantation prior to hepatic transplantation. Results We included 255 patients (50±14 years, 53% male, 52.5% treated with tafamidis and 27% had prior LT, and 10% with atrial fibrillation), 43.3% with no evidence of conduction disease, 32.3% with conduction disease, but no formal indication for pacemaker implantation and 24.4% with formal indication for pacemaker implantation. Patients with formal indication for pacemaker implantation were older, with longer duration of neurologic manifestations, with higher concentration of both Troponin T and NT-proBNP and with higher number of organs affected. In multivariate analysis, longer duration of neurologic manifestations (OR 1.090 – 95% IC: 1.036–1.145, p-value 0.001), Left ventricular (LV) maximal wall thickness (OR 1.230 – 95% CI: 1.070–1.414, p-value 0.004), neurologic staging (OR 3.420 – 95% CI: 1.443–8.104, p-value 0.005) and higher number of organs affected (OR 1.719 – 95% CI: 1.218–2.424, p-value 0.002) all showed to be independent predictors of the need for pacemaker implantation, in contrast to LV ejection fraction and serum concentration of Troponin T and NT-proBNP. We've also found a statistical significant association between conduction disease and ophthalmic manifestations. Conclusions Our findings suggest that the need for pacemaker implantation in patients with mATTR is closer linked to the duration, severity and affected number of organs than to cardiac biomarkers or echocardiographic findings. Funding Acknowledgement Type of funding source: None

The Relevance of Natorp’s Criticism of Husserl to the Hermeneutical Transformation of Heidegger’s Phenomenology

This article will show how Natorp’s criticism of Husserlian phenomenology was one of the most important triggers of the hermeneutical transformation of Heideggerian phenomenology. Concepts like hermeneutical intuition, or tools like formal indication, are the means that Heidegger worked out in order to preserve the phenomenological access to pre-theoretical life as it gives itself. The first part of this article is devoted to presenting Natorp’s criticisms of Husserl’s phenomenology and Husserl’s attempts to answer them. The second part will illustrate how Heidegger, criticizing Natorp, retrieves the validity of the phenomenological intuition and expression by opening up their original, pre-theoretical meanings. It will conclude with a few critical remarks concerning Heidegger’s attempt to describe the motivation of philosophical activity in transcendental terms.

615 Symptomatic status and outcomes in a real-world severe aortic stenosis population

Introduction Aortic stenosis (AS) is one of the most common valvular heart diseases and is now frequently diagnosed in asymptomatic patients (AP). Symptomatic patients (SP) have a higher risk of adverse events, in contrast with AP. The current guidelines recommend aortic valve replacement (AVR) for SP with severe AS (SAS), with a very poor prognosis for those conservatively managed. Purpose To evaluate the baseline characteristics, therapeutic strategies and the long-term outcomes of SP and AP with SAS in a real­-world setting. Methods Retrospective cohort study of AP and SP with SAS (mean transvalvular pressure gradient (MG) > =40 mmHg or a peak transvalvular velocity (PTV) > =4.0 m/s), who were examined in our echo lab between January 2014 and December 2016. Follow-up was 2.6 ± 1.0 years. The primary outcome was a composite of cardiovascular death or heart failure hospitalization. Results 212 patients (pts) with SAS were included (age 76.1 ± 9.1years, 31.6% men; aortic valve area 0.69 ± 0.21cm2; PTV 4.5 ± 0.4m/s; MG 48.5 ± 11.6mmHg; left ventricular ejection fraction 58.8 ± 12.2%). 154 pts (72.6%) had symptoms related to aortic stenosis. The SP had higher PTV (4.6 ± 0.5 vs 4.3 ± 0.4m/s, p < 0.0001) and MG (50.4 ± 12.2 vs 43.5 ± 7.8mmHg, p < 0.0001), less peripheral artery disease (2.6% vs 12.1%, p = 0.011), more chronic obstructive pulmonary disease (13.0% vs 1.8%, p = 0.016) and arterial hypertension (74.0% vs 56.0%, p = 0.016). AVR (surgical n = 99, transcatheter n = 13) was performed in 47.6% (n = 101) SP and 19.0% (n = 11) AP (p < 0.0001), while the remainder with a formal indication (n = 70, 33.0%) were managed conservatively. Twelve AP (36.2%) did not undergo AVR, although they had indication (4 refused, 4 due to comorbidities and 4 died). The AVR was not performed in the SP group mostly due to comorbidities (n = 23, 14.9%) and refusal (n = 22, 14.3%). Forty-four pts (20.8%) had at least one event of the primary outcome and there were no differences in the SP and AP groups (n = 36, 23.4% in SP vs n = 8, 13.4% in AP, p = 0.125). However, SP and AP who underwent to AVR had fewer events (Figure 1). Pts with at least one event were mainly female (54.5%, p = 0.026), hadn’t performed AVR (84.1% vs 15.9%, p < 0.0001), had a lower estimated glomerular filtration rate (58.4 ± 21.2 vs 66.3 ± 21.4mL/min/1.73m2, p = 0.03), higher systolic pulmonary artery pressure (45.4 ± 17.3 vs 37.8 ± 14.9mmHg, p = 0.016) and lower TAPSE (20.2 ± 4.9 vs 22.4 ± 4.2mm, p = 0.012). In the multivariate analysis, only the AVR was predictive of the outcome (HR 0.079, CI 0.028-0.227, p < 0.0001). Conclusion In a real-world experience, SAS has a high rate of adverse events. Few differences were observed between SP and AP. The AVR had a significant impact in the outcome, regardless of symptoms, thus implying that selected AP may as well benefit from this intervention. Nonetheless, in a real-world setting, more than one-third of the pts with a formal indication for intervention was conservatively treated. Abstract 615 Figure 1 Survival of SAS pts.

Heidegger’s Pursuit of Authenticity in Philosophy

The concern with authenticity exhibited by both Heidegger and Wittgenstein applies reflexively to their work: being authentic and philosophizing authentically are deeply intertwined concerns. This chapter focuses on the way in which Heidegger attempts to extricate himself from traditional philosophical problematics, focusing primarily on the problematic of realism and idealism and on the concept of truth. Heidegger develops a method of formal indication by which he tries to direct us toward an ontological understanding without relying on the problematic form of the assertion. However, Heidegger attempts at points to articulate this ontological understanding—most notoriously when he asserts that Newton’s Laws were not true before Newton—in ways that work against him.

Reading the First Epistle of John with the Method of Formal Indication

This presentation has two tasks. First, following Heidegger’s presentation of the method of formal indication in his 1920-21 lectures on the Pauline Epistles, I draw out two possible meanings for the method. On the one hand, formal indication could be a hermeneutic tool, a use of the how indicated in language to guide one in understanding the original relation in experience as original relation (enacted). On the other hand, formal indication could be the enacting of the original relation myself, in other words, appropriating the original relation in my own life as something to be enacted by me. The second task of the presentation is to read the First Epistle of John in the context of formal indication and these two possibilities, highlighting the affinities between the Epistle and the early Heidegger’s method and ultimately arguing that the dialogical imperative in John presents its necessary foil.