Investigation and treatment of lead toxicity in a galah (Eolophus roseicapilla)

Birds can be exposed to oral toxins either inside or outside of their main enclosures. The psittacine beak is adapted not only for grasping and processing food but also for climbing, therefore toxin exposure can be either deliberate (by active ingestion), or accidental. A 1-year-old male galah (Eolophus roseicapilla) was presented with a 4-day history of neurological signs including loss of balance and seizures. The bird had access to a garage and was thought to have been chewing on lead sheeting. Radiodense particles were identified in the ventriculus and high lead levels were confirmed on toxicology. Treatment was instigated with calcium disodium edetate and a full recovery was made. This case study details the investigation and treatment for a typical presentation of lead poisoning in a psittacine.

INFECTIOUS EXACERBATION OF BRONCHIECTASIS SUCCESSFULLY TREATED WITH CEFTRIAXONE/SULBACTAM/DISODIUM EDETATE-1034 (ELORES™)

ABSTRACTBronchiectasis is a type of chronic obstructive pulmonary disease, defined as permanent abnormal dilation of bronchi due to vicious cycle of transmuralinfection and inflammation. Bronchiectasis is generally characterized by cough, wheeze, and dyspnea. Pathogens responsible for bronchiectasisinclude pathogens Haemophilus influenzae, Pseudomonas aeruginosa, Streptococcus pneumoniae, Staphylococcus aureus, and nontuberculousmycobacteria. Empirical antibiotic therapy and other drugs are used empirically in the management of bronchiectasis.Here, we discuss a case ofinfectious exacerbation of bronchiectasis successfully treated with an empirical use of ceftriaxone/sulbactam/disodium edetate-1034.Keywords: Bronchiectasis, Elores™, Ceftriaxone/sulbactam/disodium edetate-1034, Disodium edetate, Antibiotic resistance.

Significance of CSE-1034 (Elores™) in Treatment of Urinary Tract Infections due to Multi Drug Resistant ESBLPositiveEscherichia coli

UTIs are one of the most common infections of geriatric patients in community acquired and hospital acquired settings. Escherichia coli(E. coli) is usually the most common pathogen responsible for UTI.Antibiotic resistance is the main reason for failure of therapy especially in E. coli. Biofilm formation, ESBL and MBL production&efflux pump over expression are the main reasons for antibiotic resistance in E. coli. That’s why management of UTI with multi drug resistant (MDR)E. coli has always been challenge for the clinicians.We are reporting empiric use of new antibiotic adjuvant entity Elores™(Ceftriaxone/ Sulbactam/Disodium-edetate) in the management of UTIs caused by multi drug resistant E. coli.