Exploring the drug loading mechanism of photoresponsive inorganic nanocarriers through molecular dynamics simulations

Inorganic nanoparticles are gaining increasing attention as drug carriers because they respond to external physical stimuli, allowing to combine therapy with diagnosis. Their drawback is a low drug loading capacity,...

Fotophoresis and laser treatment in patients with chroniceczema

The aim. To evaluate the efficiency of physiotherapeutic methods and combine therapy on immune system and on oxidation process in patientes with chronic eczema. Materials and methods. There were 32 patients with severe chronic eczema, who were treated with standard systemic and topical therapy plus photophoresis with mometasone furoat (1 mg) and supracutaneus laser irradiation of blood (1 procedure). The efficiency of therapy was detected by the changes of EASI index, cell and humoral immunity parameters, antioxidation status. Results. After using of combine therapy in severe eczema patients positive changes in severity of cutaneous process and prolongation of remission periods were found out as well as normalization of immune status and levels of oxidation processes. Conclusion. The combine treatment of patients with severe chronic eczema is effective, available method of therapy of chronic eczema patients.