Prenatal maternal and cord blood vitamin D concentrations and negative affectivity in infancy

Higher maternal vitamin D concentration during pregnancy is associated with better child mental health. Negative affectivity, an early-emerging temperamental trait, indicates an increased risk of psychopathology. We investigated if maternal early/mid-pregnancy 25-hydroxyvitamin D (25(OH)D) and neonatal cord blood 25(OH)D concentrations are associated with Negative affectivity in infancy. We studied term-born infants from the vitamin D Intervention in Infants study (VIDI, n = 777, follow-up rate 80%, Finland), and the Generation R Study (n = 1505, follow-up rate 40%, Netherlands). We measured maternal serum 25(OH)D at 6–27 weeks (VIDI) or 18–25 weeks (Generation R) of pregnancy, and cord blood 25(OH)D at birth (both cohorts). Caregivers rated infant Negative affectivity at 11.7 months (VIDI) or 6.5 months (Generation R) using the Revised Infant Behavior Questionnaire. Using linear regression, we tested associations between 25(OH)D and Negative affectivity adjusted for infant age, sex, season of 25(OH)D measurement, maternal age, education, smoking, and body-mass-index. Per 10 nmol/l increase in maternal early/mid-pregnancy 25(OH)D, infant Negative affectivity decreased by 0.02 standard deviations (95% confidence interval [CI] − 0.06, − 0.004) in VIDI, and 0.03 standard deviations (95% CI − 0.03, − 0.01) in Generation R. Cord blood 25(OH)D was associated with Negative affectivity in Generation R (− 0.03, 95% CI − 0.05, − 0.01), but not VIDI (0.00, 95% CI − 0.02, 0.02). Lower maternal 25(OH)D concentrations were consistently associated with higher infant Negative affectivity, while associations between cord blood 25(OH)D concentrations and Negative affectivity were less clear. Maternal vitamin D status during early- and mid-pregnancy may be linked with early-emerging differences in offspring behavior.

Dental Fear In Children And Ways To Overcome Them

Fears and anxieties are part of the normal development of a child, and, as a rule, developmental fears and anxieties are transient. However, for some children, dental fears and anxieties persist and become persistent and problematic. Many different mechanisms have been proposed to explain the development of CVD in children; however, there is general agreement that the aetiology of childhood CVD is multifactorial. Endogenous sources of CVD are internal factors that make people susceptible to the development of dental anxiety. It is important to understand that the influence of close family members can help or hinder treatment. Endogenous factors that can increase a person's susceptibility to CVD include genetic vulnerability, personality traits, age and gender. A high level of CVD among young people is associated with social, emotional and behavioural problems, general anxiety and the temperamental trait of negative emotionality. Having fears and anxieties is considered part of a child's normal development and follows a consistent and predictable pattern of adult life. Poor communication between the dentist and the patient not only contributes to the development of CVD but plays an important role in maintaining dental anxiety. Therefore, all members of the dental staff must be aware of how their behaviour can affect children.

Rejection sensitivity and the development of social anxiety symptoms during adolescence: A five-year longitudinal study

Rejection sensitivity is a bias toward expecting rejection that can result from negative social experiences and degrade emotional adjustment. In this study, rejection sensitivity was expected to predict patterns of adolescent social anxiety over 5 years when considered alongside other known or expected risk and protective factors: peer rejection (peer-reported), emotion dysregulation, self-worth, temperament (parent-reported), female gender, and grade. Participants were 377 Australian students (45% boys; 79% White, 15% Asian) aged 10 to 13 years ( M = 12.0, SD = .90) and their parents (84%) who completed seven repeated surveys across 5 years. In an unconditional latent growth model, social anxiety symptoms had a significant quadratic pattern of growth, with symptoms increasing about midway into the study when adolescents were age 14, on average. In a model with all predictors, rejection sensitivity was uniquely associated with a higher intercept and a more pronounced quadratic growth pattern of social anxiety symptoms. Other predictors of growth in symptoms were the temperamental trait of negativity affectivity and emotion dysregulation; negative affectivity was associated with a higher intercept and a more pronounced quadratic pattern, and emotion dysregulation was associated with a higher intercept and a less pronounced quadratic pattern. Gender was associated with the intercept, with girls higher in symptoms than boys.

The Role of Behavioral Inhibition for Conversational Speech and Language Characteristics of Preschool-Age Children Who Stutter

Purpose The purpose of this study was to investigate whether preschool-age children who stutter (CWS) were more likely to exhibit a temperamental trait of behavioral inhibition (BI), a correlate of shyness, than children who do not stutter (CWNS) and whether this temperamental trait affected preschool-age children's speech fluency and language complexity during a conversation with an unfamiliar adult. Method Sixty-eight preschool-age children (31 CWS, 37 CWNS) participated. The degree of BI was assessed by measuring the latency to their sixth spontaneous comment and the number of all spontaneous comments during a conversation with an unfamiliar examiner (following Kagan et al.'s [1987] methodology). Parent report of shyness from the Children's Behavior Questionnaire served as an indirect measure of BI. Children's language complexity was assessed by measuring their mean length of utterance and the number of words spoken. For CWS, the frequency of stuttering and the negative impact of stuttering were also assessed. Results First, we found no between-group differences in the degree of BI across the behavioral observation measures. However, CWS were rated shyer by parents than CWNS. Second, for CWS only, higher BI was associated with less complex utterances and fewer words spoken. Third, for CWS, higher BI was associated with fewer stuttered disfluencies produced. Conclusions This study provides empirical evidence that BI to the unfamiliar may have salience for childhood stuttering as it affected the quantity and quality of language spoken with an unfamiliar adult. Clinical implications of high BI for the assessment and treatment of preschool-age stuttering are discussed.

Child differential sensitivity to parental self-efficacy improvement

This study investigates the hypothesis of a child differential sensitivity to parenting improvement. One hundred and fourteen parents of preschoolers participated in two parenting micro-trials aiming to increase parental self-efficacy in view of improving child behavior. The first micro-trial took place in a short-term laboratory experiment; the other was an eight-week parenting group intervention, both focusing on altering parental cognition. Differential effects of parental self-efficacy improvement on child’s positive and negative behaviors, depending on child temperament, were compared at post-test between control and experimental groups. Both observation and questionnaires were used to measure child behavior as well as regression and Regions of Significance analyses. Child differential sensitivity was found both in the laboratory experiment and in the parenting intervention for the temperamental trait of negative emotionality but not for the temperamental trait of activity. However, this sensitivity was in an unexpected direction. Highly emotional children benefited less from this parental cognitive improvement than children low on emotionality. These results may be explained by the specific cognitive nature of these two parenting micro-trials.

An Emerging Natural History in the Development, Mechanisms and Worldwide Prevalence of Major Mental Disorders

Conciliating recent findings from molecular genetics, evolutionary biology, and clinical observations together point to new understandings regarding the mechanism, development and the persistent worldwide prevalence of major mental disorders (MMDs), which should be considered the result of an evolutionary downside trade off. Temperamental/trait variability, by facilitating choices for individual and group responses, confers robustness flexibility and resilience crucial to success of our species. Extreme temperamental variants, originating evolutionarily from the asocial aspect of human nature, also constitute the premorbid personality of the disorders. The latter create vulnerable individuals out of whom some will develop MMDs but at much higher rate to that of the general population. Significantly, similar temperamental “lopsidedness” enables many of these vulnerable individuals, if intelligent, tenacious, and curious, to be creative and contribute to our survival while some may also develop MMDs. All have a common neural-developmental origin and share characteristics in their clinical expression and pharmacological responses also expressed as mixed syndromes or alternating ones over time. Over-pruning of synaptic neurons may be considered the trigger of such occurrences or conversely, the failure to prevent them in spite of it. The symptoms of the major mental disorders are made up of antithetical substitutes as an expression of a disturbed over-all synchronizing property of brain function for all higher faculties previously unconsidered in their modeling. The concomitant presence of psychosis is a generic common occurrence.

Shared Genetic and Environmental Influences on Early Temperament and Preschool Psychiatric Disorders in Hispanic Twins

Objective: Despite an increasing recognition that psychiatric disorders can be diagnosed as early as preschool, little is known how early genetic and environmental risk factors contribute to the development of psychiatric disorders during this very early period of development. Method: We assessed infant temperament at age 1, and attention deficit hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and separation anxiety disorder (SAD) at ages 3 through 5 years in a sample of Hispanic twins. Genetic, shared, and non-shared environmental effects were estimated for each temperamental construct and psychiatric disorder using the statistical program MX. Multivariate genetic models were fitted to determine whether the same or different sets of genes and environments account for the co-occurrence between early temperament and preschool psychiatric disorders. Results: Additive genetic factors accounted for 61% of the variance in ADHD, 21% in ODD, and 28% in SAD. Shared environmental factors accounted for 34% of the variance in ODD and 15% of SAD. The genetic influence on difficult temperament was significantly associated with preschool ADHD, SAD, and ODD. The association between ODD and SAD was due to both genetic and family environmental factors. The temperamental trait of resistance to control was entirely accounted for by the shared family environment. Conclusions: There are different genetic and family environmental pathways between infant temperament and psychiatric diagnoses in this sample of Puerto Rican preschool age children.

The Need Inventory of Sensation Seeking (NISS)

Based on the conception of sensation seeking as a need rather than a temperamental trait ( Hammelstein, 2004 ), we present a new assessment method, the Need Inventory of Sensation Seeking (NISS), which is considered to assess a motivational disposition. Three studies are presented: The first examined the factorial structure and the reliability of the German versions of the NISS; the second study compared the German and the English versions of the NISS; and finally, the validity of the NISS was examined in a nonclinical study and compared to the validity of conventional methods of assessing sensation seeking (Sensation Seeking Scale – Form V; SSS-V). Compared to the SSS-V, the NISS shows better reliability and validity in addition to providing new research possibilities including application in experimental areas.