Design of a Novel Topology of Transformer-Less Cuk Inverter for Isolated Load Applications

This paper presents a new topology of single-stage inverter to generate quality sinusoidal output waveform without any additional boosting components. The proposed inverter is a combination of back-to-back two Cuk converters and hence, it is named as a cuk inverter. As per the inductor value, it can operate in continuous and discontinuous current mode. The sinusoidal output voltage can be raised or lowered with different duty ratio based on the load requirement. This Cuk inverter reduces the filter requirement in the output circuit. Further, to show the advantage of the proposed topology, a comparative study is carried out with conventional and recent converters in terms of number of switches, LC components and applications. The performance of the proposed topology is analyzed with MATLAB/Simulink tool and implemented as hardware to validate the simulated results.

CRITERIA EVALUATION OF THE LIMIT DEPTH OF HORIZONTAL PRODUCTION

The paper presents the results of a study to determine the technological contours of horizontal underground workings and the maximum safe depth of their laying. The criterion for determining the limiting depth can be the condition that there are no points on the output circuit at which the stresses the tangential normal stress exceeds the tensile and compressive strengths of the host rock. The results of solving the problem of finding fracture zones on a circular cross-section working circuit are in satisfactory qualitative agreement with the result obtained independently of the authors.

DC-DC Boost Converter for Battery Charging Application

Boost converter designed to improve output voltage with the use of coupled inductor and capacitor, two switch boost converter is connected in series with parallel to supply voltage. And output of converter is consists of two diodes and two output capacitor with load resistance. Turns ratio is 1:2 in between input and output circuit, capacitor voltage will be improved through the use of coupled inductor

Cornu Ammonis Changes Are at the Core of Hippocampal Pathology in Depression

Commentary on: Roddy DW, Farrell C, Doolin K, Roman E, Tozzi L, Frodl T, O'Keane V, O'Hanlon E. The Hippocampus in Depression: More Than the Sum of Its Parts? Advanced Hippocampal Substructure Segmentation in Depression. Biol Psychiatry. 2019 Mar 15;85(6):487-497. doi: 10.1016/j.biopsych.2018.08.021. Epub 2018 Sep 6. PubMed PMID: 30528746. The hippocampus is a key cognitive hub implicated in major depressive disorder. However, major depressive disorder neuroimaging studies have used inconsistent anatomical hippocampal definitions to estimate hippocampal volumes, leading to some heterogeneity in findings. In a recent paper, we used a novel reassembly of automated hippocampal substructures (composites) to build alternative anatomical hippocampal definitions and used these to investigate differences in a well-defined cohort of major depressive disorder patients and healthy controls. We found that the most significant differences between major depressive disorder and healthy controls were localized to the core cornu ammonis (CA) regions of the hippocampus. The CA2–4 regions were smaller in first episode major depressive disorder, whereas more widespread differences were found in recurrent/chronic major depressive disorder, suggestive of a potential disease process in major depressive disorder. In this commentary, we also show how new hippocampal composites to investigate sections of the hippocampal circuitry demonstrate that differences in major depressive disorder occur across the input, middle and output circuit nodes of the hippocampal core. Hippocampal pathology localized across the core hippocampal CA circuity may account for the diverse and wide-ranging symptoms often experienced in depression.