As COVID-19 shuttered schools, it created widespread student and family needs and exacerbated needs stemming from longstanding racial and economic inequities. Here we examine how an evidenced-based, integrated student support intervention responded to systematically identify and address the academic and non-academic needs of students and families in 94 high-poverty, urban schools. We conduct thematic analysis of open-ended survey responses about intervention personnel’s work in spring 2020 and triangulate findings with descriptive analyses of service provision records and mid-spring estimates of crucial needs. We find that schools needed a comprehensive, coordinated response to identify and meet needs, which included resource, academic, and socio-emotional support. To respond, the intervention leveraged existing practices and relationships to maintain intervention-specific practices, facilitate referrals and connections to resources, and expand direct intervention for education stakeholders. Findings elucidate effective practices for meeting academic and non-academic needs that affect student learning and may arise in future schooling disruptions.