This chapter explores collaboration with specialized instructional support personnel (SISP). It provides an overview of SISP members, including school psychologists, school resource officers, school counselors, and school nurses, and explores how school social workers can effectively work with other SISP. It demonstrates the vital importance of establishing trusting and productive working relationships with SISP in order to meet the diverse needs of students and cultivate a positive school environment. Components of interdisciplinary collaboration include trust, flexibility, interdependence, problem solving, and proactive planning. Such interdisciplinary collaboration benefits schools as well as enhancing partnerships with parents and the community. A case study highlights the importance of school social worker partnership and collaboration with SISP teams.