acanthopanax trifoliatus
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Author(s):  
Jiao LUO ◽  
Shan XIAO ◽  
Xiao-Jun LI ◽  
Xiang-Qian LIU ◽  
Ok-Kyoung KWON ◽  
...  


2021 ◽  
Vol Volume 15 ◽  
pp. 2629-2639
Author(s):  
Ping Li ◽  
Yanli Chen ◽  
Luxiang Luo ◽  
Huiwen Yang ◽  
Yufang Pan


2021 ◽  
Author(s):  
Zefeng Chen ◽  
Shupeng Cheng ◽  
Huiqiong Lin ◽  
Wenjing Wu ◽  
Liyi Liang ◽  
...  


2020 ◽  
Vol 15 (12) ◽  
pp. 1934578X2097423
Author(s):  
Sen Jiang ◽  
Dong-Li Li ◽  
Jie Chen ◽  
Xi Zheng ◽  
Pan-Pan Wu ◽  
...  

Natural products have presented potentiality to improve the outcomes of cancer therapies. Impressic acid (E12-1) and acankoreanogein (E13-1), important activity compounds in Acanthopanax trifoliatus (L.) Merr., show widely biological activities. In this study, we isolated E12-1 and E13-1 from Acanthopanax trifoliatus (L.) Merr., and investigated their improvement effect in gemcitabine (GEM) treatment in Panc-1 cells. The results showed that GEM in combination with E12-1 or E13-1 showed stronger inhibition on the growth and induction of apoptosis in Panc-1 cells compared to GEM, E12-1, or E13-1 alone. GEM in combination with E12-1or E13-1 also strongly inhibited cell migration. Mechanistic investigation showed that GEM in combination with E12-1or E13-1 effectively inhibited the activition of nuclear factor kappa-light-chain-enhancer of activated B cells and Stat 3. Overall, GEM in combination with E12-1 or E13-1 might be an effective strategy for the prevention of prostate cancer.



2020 ◽  
Vol 5 (3) ◽  
pp. 3408-3409
Author(s):  
Jingyu Li ◽  
Fang Zhou ◽  
Yu Mei ◽  
Yan Gu ◽  
Shiqang Xu ◽  
...  


2019 ◽  
Vol 10 (8) ◽  
pp. 5080-5090 ◽  
Author(s):  
Min Chen ◽  
Ying Qin ◽  
Hang Ma ◽  
Xi Zheng ◽  
Renping Zhou ◽  
...  

Two triterpenoids from Acanthopanax trifoliatus, an edible medicinal plant from Southeast Asia, attenuated lipopolysaccharides-induced inflammation in murine macrophage RAW246.7 cells and tetradecanoylphorbolacetate-induced mouse ear edema.



Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
P Sithisarn ◽  
S Muensaen ◽  
S Jarikasem


2015 ◽  
Vol 31 (10) ◽  
pp. 499-509 ◽  
Author(s):  
Tzu-Mei Chien ◽  
Po-Chow Hsieh ◽  
Shyh-Shyun Huang ◽  
Jeng-Shyan Deng ◽  
Yu-Ling Ho ◽  
...  


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