Konsep Maqasid al-Syariah dalam Konteks Game Online di Masyarakat

The current development and globalization of this decade have been marked by rapid technological advances. Human welfare, which is demanded to be better and more advanced, triggers humans to discover new findings. One of the new findings found by humans is the internet. Technological progress is one of several measures of the development and progress of a country. The logical consequence at this level is that a country must be able to respond and implement the principle of technological progress as a standard if it wants to obtain a progressive state label, regardless of whether human resources in a country are ready or not in facing challenges and consequences in the future. Online games are part of technological advances that use the internet with a mechanism to connect between players online. With this online game there are a lot of madharat and mafsadat especially for teenagers and online game players because this game can bring fatigue, illness, laziness and something negative. Perkembangan zaman dan globalisasi pada dasawarsa ini ditandai dengan kemajuan teknologi secara pesat. Kesejahteraan manusia yang dituntut untuk menjadi lebih baik dan maju memacu kreatifitas manusia dalam mencari temuan temuan baru. Temuan baru yang dihasilkan manusia adalah salah satunya internet. Kemajuan teknologi menjadi satu dari beberapa ukuran perkembangan dan kemajuan sebuah negara. Konsekwensi logis pada tataran ini, bahwa suatu negara harus mampu merespon dan menjalankan prinsip kemajuan teksnologi sebagai standar jika ingin memperoleh labelitas negara berkemajuan, terlepas apakah SDM dalam suatu negara tersebut siap atau tidak dalam menghadapi tantangan dan konsekwensi dikemudian hari.Game Online merupakan bagian dari kemajuan teknologi yang menggunakan internet dengan mekanisme menghubungkan antar pemain secara online. Dengan adanya game online ini banyak sekali madharat dan mafsadat terutama bagi para remaja dan para penggiat game online karena permainan ini bisa mendatangkan kelelahan,sakit,bermalas-malasan dan sesuatu yang bersifat negatif.

Continuous chromatin state feature annotation of the human epigenome

Semi-automated genome annotation (SAGA) methods are widely used to understand genome activity and gene regulation. These methods take as input a set of sequencing-based assays of epigenomic activity (such as ChIP-seq measurements of histone modification and transcription factor binding), and output an annotation of the genome that assigns a chromatin state label to each genomic position. Existing SAGA methods have several limitations caused by the discrete annotation framework: such annotations cannot easily represent varying strengths of genomic elements, and they cannot easily represent combinatorial elements that simultaneously exhibit multiple types of activity. To remedy these limitations, we propose an annotation strategy that instead outputs a vector of chromatin state features at each position rather than a single discrete label. Continuous modeling is common in other fields, such as in topic modeling of text documents. We propose a method, epigenome-ssm, that uses a Kalman filter state space model to efficiently annotate the genome with chromatin state features. We show that chromatin state features from epigenome-ssm are more useful for several downstream applications than both continuous and discrete alternatives, including their ability to identify expressed genes and enhancers. Therefore, we expect that these continuous chromatin state features will be valuable reference annotations to be used in visualization and downstream analysis.

Labeling and Framing: Understanding Responses to Terrorism and the Far-Right

The War on Terror narrative has created gaps in the critical understanding of terrorism studies, particularly in how the media and the state label politically motivated violence. The understanding of what terrorism means for western states has shifted dramatically after the events of September 11, 2001. With that shift, there has also been an increase in social movements that attempt to work within or work outside the current government rhetoric. However, the existence of such movements and groups and the violent acts they commit has been on the rise. This paper seeks to explore whether or not the inconsistent labeling of far-right social movement violence in western states as ‘lone wolf violence’ or ‘hate crime’ rather than ‘terrorism’ is detrimental to the critical understanding of both terrorism and counter terrorism.

The contribution of Andreas Mayer for the natural history of the State of Paraná, Brazil: V. Reptiles: relevant addenda and corrigenda

A study about the herpetological legacy of the German naturalist Andreas Mayer (1907-1986) (Bérnils & Moura-Leite, 1990) raised 83 specimens from 20 reptile species captured in the Brazilian states of Paraná and Mato Grosso do Sul (years 40, 50, and 60) and currently housed at the Museu de História Natural Capão da Imbuia (Curitiba). Just in Mayer's birth centenary, 15 more snakes collected by him and not presented in the former publication were founded. This material is relevant because (1) came from areas currently under human-altered environments; (2) was collected in areas that were poorly sampled at that time; and (3) embraced some species hard to find in Paraná, including the first occurrence of Phimophis cf. guerini for the state. Label data for the added snakes and some important corrections to the former article, with taxonomic and geographic updates, are being presented.

MORE CONCERNING LABELS

It was with interest that I read the article by Mr. Frank E. Lutz in the April number of the Canadian Entomologist entitled “Labels.”It is not so very many years ago (perhaps thity) that we were satisfied if specimens sent to us only bore a State label, the State label as first used being nothing more or less than a coloured disk, a different colour for each State. A few years more, and we have the abbreviated State labels – N.J. for New Jersey, Can. for Canada, etc. Not long after, we asked our friends to mark the label in such a mnner that we might know from what part of the State the insect came. Then it was that the collector with pen and ink would mark the label in one of the corners, or perhaps make a mark in the centre, thus designating as to what part of the State the insect had come from. This was not a bad plan, and to-day may such labeled specimens can be seen in the “Horn Collection.” as well as other collections in New York and Philadelphia.