Simulation of Optical Nano-Manipulation with Metallic Single and Dual Probe Irradiated by Polarized Near-Field Laser

Nano-manipulation technology, as a kind of “bottom-up” tool, has exhibited an excellent capacity in the field of measurement and fabrication on the nanoscale. Although variety manipulation methods based on probes and microscopes were proposed and widely used due to locating and imaging with high resolution, the development of non-contacted schemes for these methods is still indispensable to operate small objects without damage. However, optical manipulation, especially near-field trapping, is a perfect candidate for establishing brilliant manipulation systems. This paper reports about simulations on the electric and force fields at the tips of metallic probes irradiated by polarized laser outputted coming from a scanning near-field optical microscope probe. Distributions of electric and force field at the tip of a probe have proven that the polarized laser can induce nanoscale evanescent fields with high intensity, which arouse effective force to move nanoparticles. Moreover, schemes with dual probes are also presented and discussed in this paper. Simulation results indicate that different combinations of metallic probes and polarized lasers will provide diverse near-field and corresponding optical force. With the suitable direction of probes and polarization direction, the dual probe exhibits higher trapping force and wider effective wavelength range than a single probe. So, these results give more novel and promising selections for realizing optical manipulation in experiments, so that distinguished multi-functional manipulation systems can be developed.

Resonator nanophotonic standing-wave array trap for single-molecule manipulation and measurement

Nanophotonic tweezers represent emerging platforms with significant potential for parallel manipulation and measurements of single biological molecules on-chip. However, trapping force generation represents a substantial obstacle for their broader utility. Here, we present a resonator nanophotonic standing-wave array trap (resonator-nSWAT) that demonstrates significant force enhancement. This platform integrates a critically-coupled resonator design to the nSWAT and incorporates a novel trap reset scheme. The nSWAT can now perform standard single-molecule experiments, including stretching DNA molecules to measure their force-extension relations, unzipping DNA molecules, and disrupting and mapping protein-DNA interactions. These experiments have realized trapping forces on the order of 20 pN while demonstrating base-pair resolution with measurements performed on multiple molecules in parallel. Thus, the resonator-nSWAT platform now meets the benchmarks of a table-top precision optical trapping instrument in terms of force generation and resolution. This represents the first demonstration of a nanophotonic platform for such single-molecule experiments.

Numerical Analysis of Optical Trapping Force Affected by Lens Misalignments

Geometrical optics approximation is a classic method for calculating the optical trapping force on particles whose sizes are larger than the wavelength of the trapping light. In this study, the effect of the lens misalignment on optical force was analyzed in the geometrical optics regime. We used geometrical optics to analyze the influence of off-axis placement and the tilt of the lens on the trapping position and stiffness in an optical trap. Numerical calculation results showed that lens tilting has a greater impact on the optical trap force than the off-axis misalignments, and both misalignments will couple with each other and cause a shift of the equilibrium point and the asymmetry of the optical trap stiffness in different ways. Our research revealed the asymmetry in optical traps caused by lens misalignment and can provide guidance for optimize lens placement in future experiments.

Plasmonic elliptical nanoholes for chiroptical analysis and enantioselective optical trapping

Under linearly polarized illumination, a well-designed elliptical nanohole concurrently offers chiral near field and enantioselective optical trapping force to attract/repel the chiral target.