In view of the inaccuracy of traditional methods for solving nonlinear equations with variable coefficients in parallel, a new method for solving nonlinear equations with variable coefficients is proposed. Using the generalized symmetry group, the variable coefficient of the equation is taken as a new variable which is the same as the state of the original actual physical field. Some relations between variable coefficient equations and their solutions are found. This paper analyzes the meaning of linear differential equation and nonlinear differential equation, the difference between linear differential equation and nonlinear differential equation and their role in physics, and the necessity of solving nonlinear differential equation. By solving the nonlinear equation with variable coefficients, it can be seen that the general methods to solve the nonlinear equation include scattering inversion, Backlund transform and traveling wave solution. Based on the existing methods for solving nonlinear equations with variable coefficients, the homogeneous balance method is combined with the improved truncated expansion method, truncated expansion method and function reduction method, and the Hopf Cole transform and trial function are combined respectively. The above three methods are used to solve nonlinear equations with variable coefficients. Based on KdV Painleve principle, a parallel method for solving nonlinear equations with variable coefficients is proposed. Finally, it is proved that the method is accurate and effective for the parallel solution of nonlinear equations with variable coefficients.