A retrospective study of reproductive disorders in female dogs from the city of Uberlândia, Minas Gerais, Brazil

Diseases of the reproductive system are common in both sexes in the most varied of species. In female dog, these diseases produce different degrees of morbidity and mortality and are influenced by environmental conditions, reproductive history, and previous drug treatments. Reproductive disease may have different consequences, ranging from the absence of clinical signs to the impairment of fertility. The objective of this study was to determine the causes of reproductive diseases in female dogs admitted to the Veterinary Hospital, Federal University of Uberlândia, during a six-year period (2012-2017) and to identify the most frequently occurring diseases. Information relative to the species, age, breed, and sex of 32,944 were obtained for animals. Of these, 16,480 were female dogs and 1,185 were diagnosed with alterations to the reproductive system. The animals were divided into four groups according to age (puppies, young adults, adults, and old) and disease of the reproductive system (Group 1 - vaginal and vulvar alterations; Group 2 - alterations to the estrous cycle, ovary, and uterus; Group 3 - alterations to the gestational period and parturition). The highest occurrence of diagnoses (47%) was recorded in young adult female dogs (1 to 5 years old). The most frequent alterations in female dogs were pyometra (48.8%), dystocia (13.6%), and transmissible venereal tumor (TVT) (12.6%). Crossbred dogs were the most affected with alterations to the reproductive system, representing 60% of all the female dogs diagnosed with any pathologic alteration. In conclusion, a 7.2% occurrence of reproductive disorders shows the relevance of these diseases in small animals and suggests that new methods are needed for the prevention, early diagnosis, and treatment of these disorders.

Relation Between Episiotomy and Osteomioarticular Symptoms

Childbirth is a social and cultural phenomenon which has faced drastic changes from twentieth century as a shift to a gynecological position and an episiotomy routine. Fascia represents “the philosophy of the body” and any pathologic alteration in that tissue will affect the whole body. This study aims to verify the relation between episiotomy and osteomioarticular symptoms. 60 women who participated in this study were divided equally into two groups: group I (vaginal delivery with episiotomy) and group II (vaginal delivery without episiotomy). To assess them, we used an Initial assessment form and a Nordic Musculoskeletal Questionnaire. The data were analyzed with the Spearman Correlation Test and t Student Test for independent samples with a statistical significance of p≤0,05. Based on the results of the study, 60% women from group I related low back repercussions during the last year, while 53% women from group I related hip/lower limbs repercussions during the last week. Level of pain and musculoskeletal complaints prevailed in group I, as well. We concluded that there is a high prevalence of osteomioarticular symptoms in women who had episiotomy in her deliveries.

Role of Adipokines in Atherosclerosis: Interferences with Cardiovascular Complications in Rheumatic Diseases

Patients with rheumatic diseases have an increased risk of mortality by cardiovascular events. In fact, several rheumatic diseases such as rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus, and ankylosing spondylitis are associated with a higher prevalence of cardiovascular diseases (CVDs). Although traditional cardiovascular risk factors have been involved in the pathogenesis of cardiovascular diseases in rheumatic patients, these alterations do not completely explain the enhanced cardiovascular risk in this population. Obesity and its pathologic alteration of fat mass and dysfunction, due to an altered pattern of secretion of proinflammatory adipokines, could be one of the links between cardiovascular and rheumatic diseases. Indeed, the incidence of CVDs is augmented in obese individuals with rheumatic disorders. Thus, in this paper we explore in detail the relationships among adipokines, rheumatic diseases, and cardiovascular complications by giving to the reader a holistic vision and several suggestions for future perspectives and potential clinical implications.

Potentialities of the ultrasonic examination by detection of the pain syndrome relapse causes in the late period of the disk herniation surgical treatment

Checkup of 63 patients with pain syndrome relapse in the late period of disk herniation surgery by posterior approach. Among them there were 38 women (60,3%) and 25 men (39,7%). Middle age (44,3 ± 1,1) years. Ultrasonic examination was carried on the ultrasound scanner «Sonoline-Elegka» («Siemens») with the multi — frequency sensor 2,5—5,0 megahertz. Ultrasonography displays in the late period of the disk herniation surgery in 65,1% cases disk herniation and protrusion, in 23,8% cases — the spinal canal stenosis, in 44,4% — radicular canals stenosis, in 46% cases — cicatrical epiduritis visualization. These pathologic alteration and combination of them are the main causes of the pain relapse in the late period of the disk herniation surgery.

Pharmacologic Treatment of Migraine

The vascular theory of migraine proposed by Wolff, attributing migrainous symptoms to paroxysmal constriction and dilation of the cranial vasculature, held sway for over four decades and even now remains embraced by many clinicians and the lay public. Recent investigations, however, suggest that this proposed mechanism is untenable; although changes in blood vessel caliber and blood flow do occur in some patients during some attacks, they are not required for the production of migrainous symptoms and appear to be largely epiphenomena, occurring subsequent (and consequent) to another primary process. Evidence is mounting that migraine may result from a pathologic alteration of neurotransmission within the brain stem and trigeminovascular system, and one of the neurotransmitters primarily involved is serotonin. This has led to an explosion of interest in therapeutic agents which influence serotoninergic receptors, and the astounding success enjoyed by the first of these agents to be utilized clinically (sumatriptan and dihydroergotamine) and their offspring suggests that our understanding of this common and vexing problem will increase and be paralleled by the identification of yet more specific and effective treatment intervention.

Active Transport Dacryocystography in Evaluating Lacrimal Drainage System after Rhinoplasty

In order to evaluate the effects of lateral osteotomies performed during rhinoplastic surgery on the lacrimal drainage system, a new technique for imaging the lacrimal passages, Active Transport Dacryocystography, was applied in a total of 16 patients. In all cases, free passage of contrast media from the punctum to the inferior meatus was observed. We did not record any pathologic alteration such as mucosal edema or discontinuity of the bony structure that would have resulted in nasolacrimal obstruction.