To facilitate the use of biomethane in existing transmission and distribution infrastructures, CEN/TC 408 developed specifications (EN 16723) for injecting biomethane into the natural gas grids and using it as a transport fuel. Currently, the test methods cited in EN 16723 lack metrological aspects and have not been specifically developed for biomethane. To address this need, ISO/TC193/SC1/WG25 “Biomethane” has been created to work on standardized methods. To assess conformity of biomethane with the specification and to provide essential input to WG25, test methods are being developed in this research for a group of impurities such as siloxanes, halogenated volatile organic compounds, hydrogen chloride, hydrogen fluoride. A further objective of this research is to develop fit-for-purpose measurement standards for these parameters, to enable SI-traceable calibration and facilitate accurate measurement results. An overview of the progress made with respect to the development of measurement standards and test methods for trace level concentrations of impurities is presented, with a focus on static measurement standards of siloxanes and halogenated volatile organic compounds, dynamic gas standards of HCl and HF, as well as corresponding test methods based on gas chromatography and spectroscopic techniques. The work presented is pivotal for the development of metrological infrastructure for biomethane conformity assessment.