Taste and chemical composition as drives for utilitarian redundancy and equivalence: a case study in local medical systems in Northeastern Brazil

Background We aimed to verify whether the taste and chemical composition influence the selection of plants in each medicinal category, whether within a socio-ecological system or between different socio-ecological systems. To this end, we use the theoretical bases of the Utilitarian Redundancy Model and the Utilitarian Equivalence Model. We studied the local medical systems of four rural communities in northeastern Brazil, used as models to test our assumptions. Methods The data on medicinal plants and local therapeutic function were obtained from semi-structured interviews associated with the free-listing method, allowing to generate indexes of similarity of therapeutic use between the plants cited in each region. During the interviews, each informer was also asked to report the tastes of the plants cited. Subsequently, we classified each plant in each region according to the most cited taste. The data about the chemical composition of each plant were obtained from a systematic review, using Web of Knowledge and Scopus databases. Results Pairs of plants with similar tastes are 1.46 times more likely to have the same therapeutic function within a local medical system (redundancy), but not between medical systems (equivalence). We also find that chemical compounds are not primarily responsible for utilitarian redundancy and equivalence. However, there was a tendency for alkaloids to be doubly present with greater expressiveness in pairs of equivalent plants. Conclusions The results indicate that each social group can create its means of using the organoleptic characteristics as clues to select new species as medicinal. Furthermore, this study corroborates the main prediction of the Utilitarian Equivalence Model, that people in different environments choose plants with traits in common for the same functions.

Improved Powder Equivalence Model for the Mix Design of Self-Compacting Concrete with Fly Ash and Limestone Powder

The use of fly ash (FA) limestone and powder (LP) in combination with cement in concrete has several practical, ecological, and economic advantages by reducing carbon dioxide emissions, reducing the excessive consumption of natural resources, and contributing to a cleaner production of self-compacting concrete (SCC). A mix design method for SCC based on paste rheological threshold theory can guide the SCC mix design by paste tests. This method can be visualized by the self-compacting paste zone (SCP zone), a plane area where all the mix points meet the paste threshold theory, and SCC zone, a plane area consisting of all the mix points satisfying the criteria of qualified SCC. In the case of cement SCC, the SCP zone coheres with the SCC zone. However, in the case of the addition of FA or LP with different granulometry and shape characteristics from cement, experimental results indicate that the SCP zone is separated from the SCC zone. This work quantitatively studied the influence of FA and LP on the movement of the SCP zone by introducing the improved powder equivalence model. The improved model was obtained by powder equivalence coefficients calculated through the mortar test results with or without FA or LP, instead of SCC tests in the former method. The equivalence coefficients by volume of FA and LP are 0.55 and 0.79, respectively, which means that 1.82 unit volume of FA or 1.27 unit volume of LP is equivalent to one unit volume of cement. The improved powder equivalence model was verified by the successful preparation of SCC incorporating FA or LP simply and effectively. The equivalent SCP zone cohered better with the SCC zone than the former SCP zone, which could guide the quick mix design of SCC without SCC premix tests.

A Novel Error Equivalence Model on the Kinematic Error of the Linear Axis of High-End Machine Tool

The kinematic errors of the linear axis play a key role in machining precision of high-end CNC (Computer Numerical Control) machine tool. The quantification of error relationship is still an urgent problem to be solved in the assembly process of the linear axis, especially considering the effect of the elastic deformation of rollers. A systematic error equivalence model of slider is proposed to improve the prediction accuracy for kinematic errors of the linear axis which contains the base, the linear guide rail and carriage. Firstly, the geometric errors of assembly surface of linear guide rail are represented by small displacement torsor. According to the theory of different motion of robots, the error equivalence model of a single slider is established, namely the geometric error of assembly surface of linear guide rail and the pose error of slider is equivalent to the elastic deformation of roller. Based on the principle of vector summation, the kinematic error of a single slider is mapped to the carriage and the kinematic error of the linear axis is obtained. Besides, experiments validation of kinematic error model of the linear axis is carried out. It is indicated that the proposed model is accurate and feasible. The proposed model can provide an accurate guidance for the manufacturing and operation performance of the linear axis in quantification, and a more effective reference for the engineers at the design and assembly stage.

Self-Assembled Thermoresponsive Nanogel from Grafted Hyaluronic Acid as a Biocompatible Delivery Platform for Curcumin with Enhanced Drug Loading and Biological Activities

A hyaluronic acid-grafted poly(N-isopropylacrylamide) (HA-pNIPAM) was synthesized as a polymeric nanogel platform for encapsulation and delivery of hydrophobic bioactive compounds using curcumin as a model drug. As demonstrated by transmission electron microscopy and dynamic light scattering techniques, the HA-pNIPAM was simply assembled into spherical nano-sized particles with the thermoresponsive behavior. The success of curcumin aqueous solubilization was confirmed by fluorescent spectroscopy. The resulting nanogel formulation enhanced the aqueous solubility and uptake into NIH-3T3 cells of curcumin. This nanogel formulation also demonstrates cytocompatibility against NIH-3T3 cells, which deems it safe as a delivery vehicle. Moreover, the formulation has a slight skin-protection effect using an artificial skin equivalence model. The curcumin-loaded HA-pNIPAM nanogel showed an anti-proliferative activity against MDA-MB-231, Caco-2, HepG2, HT-29, and TNF-α-induced hyperproliferation of keratinocyte (HaCaT) cells. The thermoresponsive HA-pNIPAM nanogel reported here could be further optimized as a platform for controlled-release systems to encapsulate pharmaceuticals for therapeutic applications.

A COMPLEX MODEL OF THE WILD NATURE DOCUMENTARY AVT ANALYSIS

The article aims at presenting a complex model of the nature documentary AVT (audiovisual translation) analysis. Lambert – van Gorp’s scheme and V. Komissarov’s complex model are widely used and applied to analyzing translation. Those two models make up the basis of AVT analysis. In accordance with Lambert – van Gorp’s scheme, the preliminary data, macro-level, micro-level and systemic context of the nature documentary AVT are studied. V. Komissarov’s five-level equivalence model is also implemented in a complex model of the nature documentary AVT analysis, that model analyzes the equivalence of translation of an audiovisual work at every level and suggests translation strategies to achieve it. The article focuses on the fact that when analyzing the linguistic component of the AVT of a documentary film, it is impossible to negate the audiovisual component. In that regard, audiovisual components and how to translate them into the language of the host country are considered. The audiovisual component implies four codes: music, sound, iconographic and mobility, which are meticulously studied in the article. Following the research the author undertakes the complex model of the wild nature documentary AVT analysis.

“How Well Does Your Structural Equation Model Fit Your Data?”: Is Marcoulides and Yuan’s Equivalence Test the Answer?

Marcoulides and Yuan have introduced an equivalence test to assess structural equation model fit as an inferential alternative to Hu and Bentler’s descriptive cut-points. A procedural demonstration of how to conduct and interpret an equivalence model fit test, concluding caveats, and future research possibilities are offered.

Velar softening

In so far as velar softening is a two-stage process involving velar palatalization and velar assibilation, it is claimed that these two sound-change mechanisms ought to be analysed separately. A distinction is made between front velar stop productions, and the (alveolo)palatal stop outcome of gestural blending between velar stops and front vocalic realizations. The chapter also presents and evaluates two general models of velar softening, i.e., the articulation-based model proposed by the Neogrammarians and the acoustic equivalence model proposed by Ohala and colleagues. Several arguments in support of the former model are presented, which are based on articulatory evidence and on experimental findings reported in earlier acoustico-perceptual studies.

Introduction

The chapter deals with the origin and phonetic causes of sound changes involving consonants, with the diachronic pathways connecting the input and output phonetic forms, and with models of sound change (e.g., Evolutionary Phonology, the Neogrammarian’s articulatory model, Ohala’s acoustic equivalence model). The need to use articulatory and acoustic data for ascertaining the causes of sound change (and in particular the palatalization and assibilation of velar, labial, and dentoalveolar obstruents) is emphasized. The chapter is also concerned with how allophones are phonologized in sound-change processes and with the special status of (alveolo)palatal stops regarding allophonic phonologization.