Science Forum: Building a community to engineer synthetic cells and organelles from the bottom-up

Employing concepts from physics, chemistry and bioengineering, 'learning-by-building' approaches are becoming increasingly popular in the life sciences, especially with researchers who are attempting to engineer cellular life from scratch. The SynCell2020/21 conference brought together researchers from different disciplines to highlight progress in this field, including areas where synthetic cells are having socioeconomic and technological impact. Conference participants also identified the challenges involved in designing, manipulating and creating synthetic cells with hierarchical organization and function. A key conclusion is the need to build an international and interdisciplinary research community through enhanced communication, resource-sharing, and educational initiatives.

Implementasi Kebijakan Pusat Kesejahteraan Sosial Anak Integratif Di Kabupaten Jombang

This study aims to determine the implementation of the policy of an integrative child social welfare center in Jombang Regency. The research method used is a qualitative descriptive method using George Charles Edward's theory of policy implementation, which consists of several variables that affect the success of a policy implementation, including communication, resource sources, disposition, and the structure of the brokerage. The result that Dieh found in this research is that the implementation is less than optimal. In the aspect of communication, socialization has not been carried out to the community and the communication that has been carried out has not been optimally carried out to internal implementers. In the aspect of resources, it was found that there was a lack of staff resources. In the aspect of disposition, it was found that the understanding of implementers regarding policies was not the same. And in the aspect of the bureaucratic structure, it was found that the Standard Operating Procedure (SOP) has not been resolved as a policy implementation guideline.

Language as a communication resource and its place in the representation of world practices

The paper considers language as a communication resource and its place in the representation of world practices is evaluated from the standpoint of a philosophical and linguistic approach. The authors note that discussions of language are necessarily based on ontological, sometimes contradictory ideas about languages or language use. These reports are not limited to categories that attempt to describe and analyze them. Moving forward, there are still opportunities for more interaction with language ontologies. Thinking in the ontological register is not an interpretation or description, but rather, much more importantly, it is the identification and display of hypotheses hidden in the world of language. Researchers insist on assigning ontological significance to various practices and regulations. This requires moving away from ideological analysis and the assumption that they represent multiple points of view that illuminate various partial aspects of an independently existing and ultimately determined phenomenon, and towards an approach that aims to purify reality - worlds - as created through practices. It can be stated that specific ways of perceiving a language are more complex and, therefore, more comprehensive descriptions of languages. It is inevitable that contradictory ideas about language can coexist.

Building a community to engineer synthetic cells and organelles from the bottom-up

Empowered by emerging concepts from physics, chemistry, and bioengineering, learning-by-building approaches have found increasing application in the life sciences. Particularly, they are directed to tackle the overarching goal of engineering cellular life from scratch. The SynCell2020/21 conference brought together a diverse group of researchers to share progress and chart the course of this field. Participants identified key steps to design, manipulate, and create cell-like entities, especially those with hierarchical organization and function. This article highlights achievements in the field, including areas where synthetic cells are having socioeconomic and technological impact. Guided by input from early-career researchers, we identify challenges and opportunities for basic science and technological applications of synthetic cells. A key conclusion is the need to build an integrated research community through enhanced communication, resource-sharing, and educational initiatives. Development of an international and interdisciplinary community will enable transformative outcomes and attract the brightest minds to contribute to the field.